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PMID:17395793
From GONUTS
Koussevitzky, S, Nott, A, Mockler, TC, Hong, F, Sachetto-Martins, G, Surpin, M, Lim, J, Mittler, R and Chory, J (2007) Signals from chloroplasts converge to regulate nuclear gene expression.Science 316:715-9
| Abstract | Plastid-to-nucleus retrograde signaling coordinates nuclear gene expression with chloroplast function and is essential for the photoautotrophic life-style of plants. Three retrograde signals have been described, but little is known of their signaling pathways. We show here that GUN1, a chloroplast-localized pentatricopeptide-repeat protein, and ABI4, an Apetala 2 (AP2)-type transcription factor, are common to all three pathways. ABI4 binds the promoter of a retrograde-regulated gene through a conserved motif found in close proximity to a light-regulatory element. We propose a model in which multiple indicators of aberrant plastid function in Arabidopsis are integrated upstream of GUN1 within plastids, which leads to ABI4-mediated repression of nuclear-encoded genes. |
| Links | PubMed Online version:1140516 10.1126/science. 1140516 |
Significance
Annotations
| Gene product | Qualifier | GO ID | GO term name | Evidence Code | with/from | Aspect | Notes | Status |
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| edit table |
See also
References
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