GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
PMID:16865359
| Citation |
Lagathu, C, Yvan-Charvet, L, Bastard, JP, Maachi, M, Quignard-Boulangé, A, Capeau, J and Caron, M (2006) Long-term treatment with interleukin-1beta induces insulin resistance in murine and human adipocytes. Diabetologia 49:2162-73 |
|---|---|
| Abstract |
Adipose tissue inflammation has recently been implicated in the pathogenesis of insulin resistance and is probably linked to high local levels of cytokines. IL1B, a proinflammatory cytokine, may participate in this alteration. |
| Links |
PubMed Online version:10.1007/s00125-006-0335-z |
| Keywords |
3T3 Cells; Adipocytes/drug effects; Adipocytes/metabolism; Adiponectin/metabolism; Adiponectin/secretion; Adipose Tissue/cytology; Adipose Tissue/drug effects; Adipose Tissue/metabolism; Animals; Blotting, Western; Cells, Cultured; Cytokines/metabolism; Dose-Response Relationship, Drug; Glucose/metabolism; Humans; Inflammation/metabolism; Insulin/pharmacology; Insulin Resistance; Interleukin-1beta/genetics; Interleukin-1beta/metabolism; Interleukin-1beta/pharmacology; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Reverse Transcriptase Polymerase Chain Reaction; Time Factors |
| edit table |
Significance
Annotations
| Gene product | Qualifier | GO ID | GO term name | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| edit table |
See also
References
See Help:References for how to manage references in GONUTS.
