The Spring 2012 season of CACAO has started!
PMID:11252894
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Kirchhausen, T (2000) Three ways to make a vesicle.Nat. Rev. Mol. Cell Biol. 1:187-98
Cargo molecules have to be included in carrier vesicles of different forms and sizes to be transported between organelles. During this process, a limited set of proteins, including the coat proteins COPI, COPII and clathrin, carries out a programmed set of sequential interactions that lead to the budding of vesicles. A general model to explain the formation of coated vesicles is starting to emerge but the picture is more complex than we had imagined.
PubMed
