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MYCTU:KGD
Contents |
| Species (Taxon ID) | Mycobacterium tuberculosis. (taxon:1773) | |
| Gene Name(s) | kgd | |
| Protein Name(s) |
| |
| External Links | ||
| UniProt Identifier | KGD_MYCTU | |
| UniProt Accessions | O50463, Q7D8I9, | |
| EMBL | BX842576, AE000516, | |
| PIR | G70953, | |
| RefSeq | NP_215764.2, NP_335730.1, | |
| Pfam | PF00198, PF00676, PF02779, | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0008683 |
2-oxoglutarate decarboxylase activity |
IDA: Inferred from Direct Assay |
F |
complete | ||||
| GO:0000287 |
magnesium ion binding |
IDA: Inferred from Direct Assay |
F |
|||||
| GO:0004591 |
oxoglutarate dehydrogenase (succinyl-transferring) activity |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
|||||
| GO:0005886 |
plasma membrane |
IDA: Inferred from Direct Assay |
C |
|||||
| GO:0006096 |
glycolysis |
IEA: Inferred from Electronic Annotation |
P |
|||||
| GO:0006099 |
tricarboxylic acid cycle |
IEA: Inferred from Electronic Annotation |
P |
|||||
| GO:0006099 |
tricarboxylic acid cycle |
IDA: Inferred from Direct Assay |
P |
|||||
| GO:0008152 |
metabolic process |
IEA: Inferred from Electronic Annotation |
P |
|||||
| GO:0008152 |
metabolic process |
IEA: Inferred from Electronic Annotation |
P |
|||||
| GO:0008683 |
2-oxoglutarate decarboxylase activity |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0008683 |
2-oxoglutarate decarboxylase activity |
IDA: Inferred from Direct Assay |
F |
|||||
| GO:0009055 |
electron carrier activity |
IDA: Inferred from Direct Assay |
F |
|||||
| GO:0016624 |
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0016829 |
lyase activity |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0016831 |
carboxy-lyase activity |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0030976 |
thiamine pyrophosphate binding |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0040007 |
growth |
IMP: Inferred from Mutant Phenotype |
P |
|||||
| GO:0045254 |
pyruvate dehydrogenase complex |
IDA: Inferred from Direct Assay |
C |
|||||
| GO:0055114 |
oxidation-reduction process |
IEA: Inferred from Electronic Annotation |
P |
|||||
| GO:0055114 |
oxidation-reduction process |
IDA: Inferred from Direct Assay |
P |
|||||
| GO:0055114 |
oxidation-reduction process |
IDA: Inferred from Direct Assay |
P |
|||||
|
NOT |
GO:0004591 |
oxoglutarate dehydrogenase (succinyl-transferring) activity |
IDA: Inferred from Direct Assay |
F |
| |||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Tian J et al. (2005) Variant tricarboxylic acid cycle in Mycobacterium tuberculosis: identification of alpha-ketoglutarate decarboxylase. Proc Natl Acad Sci U S A 102: 10670-5 PubMed GONUTS page
- ↑ O'Hare HM et al. (2008) Regulation of glutamate metabolism by protein kinases in mycobacteria. Mol Microbiol 70: 1408-23 PubMed GONUTS page
- ↑ Mawuenyega KG et al. (2005) Mycobacterium tuberculosis functional network analysis by global subcellular protein profiling. Mol Biol Cell 16: 396-404 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Tian J et al. (2005) Mycobacterium tuberculosis appears to lack alpha-ketoglutarate dehydrogenase and encodes pyruvate dehydrogenase in widely separated genes. Mol Microbiol 57: 859-68 PubMed GONUTS page
- ↑ Sassetti CM et al. (2003) Genes required for mycobacterial growth defined by high density mutagenesis. Mol Microbiol 48: 77-84 PubMed GONUTS page