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MYCTU:KATG
Contents |
| Species (Taxon ID) | Mycobacterium tuberculosis. (1773) | |
| Gene Name(s) | katG | |
| Protein Name(s) | Catalase-peroxidase
CP Peroxidase/catalase | |
| External Links | ||
| UniProt | Q08129 | |
| EMBL | X68081 U06258 U40593 U40595 U41305 U41306 U41307 U41308 U41309 U41310 U41311 U41312 U41313 U41314 BX842578 AE000516 AF002194 L14268 | |
| PIR | A70519 | |
| RefSeq | NP_216424.1 NP_336417.1 | |
| PDB | 1SFZ 1SJ2 2CCA 2CCD | |
| PDBsum | 1SFZ 1SJ2 2CCA 2CCD | |
| ProteinModelPortal | Q08129 | |
| SMR | Q08129 | |
| PeroxiBase | 3551 | |
| EnsemblBacteria | EBMYCT00000003183 EBMYCT00000072645 | |
| GeneID | 885638 923602 | |
| GenomeReviews | AE000516_GR AL123456_GR | |
| KEGG | mtc:MT1959 mtu:Rv1908c | |
| PATRIC | 18126074 | |
| TIGR | MT1959 | |
| TubercuList | Rv1908c | |
| GeneTree | EBGT00050000017549 | |
| OMA | GPEVIWT | |
| PhylomeDB | Q08129 | |
| ProtClustDB | PRK15061 | |
| DrugBank | DB00609 DB00951 | |
| GO | GO:0005829 GO:0005576 GO:0005886 GO:0004096 GO:0020037 GO:0070404 GO:0070402 GO:0016677 GO:0042803 GO:0042744 GO:0045739 GO:0046677 | |
| HAMAP | MF_01961 | |
| InterPro | IPR000763 IPR010255 IPR002016 IPR019794 IPR019793 | |
| KO | K03782 | |
| Pfam | PF00141 | |
| PRINTS | PR00460 PR00458 | |
| SUPFAM | SSF48113 | |
| TIGRFAMs | TIGR00198 | |
| PROSITE | PS00435 PS00436 PS50873 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004096 |
catalase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004096 |
catalase activity |
IDA: Inferred from Direct Assay |
|
F |
Seeded From UniProt |
|||
| GO:0004096 |
catalase activity |
IDA: Inferred from Direct Assay |
|
F |
Seeded From UniProt |
|||
| GO:0004096 |
catalase activity |
IDA: Inferred from Direct Assay |
|
F |
Seeded From UniProt |
|||
| GO:0004601 |
peroxidase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004601 |
peroxidase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004601 |
peroxidase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004601 |
peroxidase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004601 |
peroxidase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004601 |
peroxidase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004601 |
peroxidase activity |
IDA: Inferred from Direct Assay |
|
F |
Seeded From UniProt |
|||
| GO:0005576 |
extracellular region |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0005829 |
cytosol |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0005829 |
cytosol |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0005886 |
plasma membrane |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0005886 |
plasma membrane |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0006979 |
response to oxidative stress |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006979 |
response to oxidative stress |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006979 |
response to oxidative stress |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006979 |
response to oxidative stress |
IMP: Inferred from Mutant Phenotype |
|
P |
Seeded From UniProt |
|||
| GO:0016491 |
oxidoreductase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0016677 |
oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor |
IDA: Inferred from Direct Assay |
|
F |
Seeded From UniProt |
|||
| GO:0020037 |
heme binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0020037 |
heme binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0020037 |
heme binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0020037 |
heme binding |
IDA: Inferred from Direct Assay |
|
F |
Seeded From UniProt |
|||
| GO:0020037 |
heme binding |
IDA: Inferred from Direct Assay |
|
F |
Seeded From UniProt |
|||
| GO:0042744 |
hydrogen peroxide catabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0042744 |
hydrogen peroxide catabolic process |
IDA: Inferred from Direct Assay |
|
P |
Seeded From UniProt |
|||
| GO:0042744 |
hydrogen peroxide catabolic process |
IDA: Inferred from Direct Assay |
|
P |
Seeded From UniProt |
|||
| GO:0042803 |
protein homodimerization activity |
IPI: Inferred from Physical Interaction |
F |
Seeded From UniProt |
||||
| GO:0042803 |
protein homodimerization activity |
IPI: Inferred from Physical Interaction |
F |
Seeded From UniProt |
||||
| GO:0042803 |
protein homodimerization activity |
IPI: Inferred from Physical Interaction |
F |
Seeded From UniProt |
||||
| GO:0045739 |
positive regulation of DNA repair |
IGI: Inferred from Genetic Interaction |
|
P |
Seeded From UniProt |
|||
| GO:0046677 |
response to antibiotic |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0046872 |
metal ion binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0055114 |
oxidation-reduction process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0055114 |
oxidation-reduction process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0055114 |
oxidation-reduction process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0055114 |
oxidation-reduction process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0055114 |
oxidation-reduction process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0055114 |
oxidation-reduction process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0070402 |
NADPH binding |
IDA: Inferred from Direct Assay |
|
F |
Seeded From UniProt |
|||
| GO:0070404 |
NADH binding |
IDA: Inferred from Direct Assay |
|
F |
Seeded From UniProt |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Zhang Z et al. (2002) Direct voltammetry and catalysis with Mycobacterium tuberculosis catalase-peroxidase, peroxidases, and catalase in lipid films. Anal Chem 74: 163-70 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Johnsson K et al. (1997) Overexpression, purification, and characterization of the catalase-peroxidase KatG from Mycobacterium tuberculosis. J Biol Chem 272: 2834-40 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Nagy JM et al. (1997) Purification and characterization of recombinant catalase-peroxidase, which confers isoniazid sensitivity in Mycobacterium tuberculosis. J Biol Chem 272: 31265-71 PubMed GONUTS page
- ↑ Målen H et al. (2007) Comprehensive analysis of exported proteins from Mycobacterium tuberculosis H37Rv. Proteomics 7: 1702-18 PubMed GONUTS page
- ↑ Banu S et al. (2002) Are the PE-PGRS proteins of Mycobacterium tuberculosis variable surface antigens? Mol Microbiol 44: 9-19 PubMed GONUTS page
- ↑ 6.0 6.1 Mawuenyega KG et al. (2005) Mycobacterium tuberculosis functional network analysis by global subcellular protein profiling. Mol Biol Cell 16: 396-404 PubMed GONUTS page
- ↑ Gu S et al. (2003) Comprehensive proteomic profiling of the membrane constituents of a Mycobacterium tuberculosis strain. Mol Cell Proteomics 2: 1284-96 PubMed GONUTS page
- ↑ Manca C et al. (1999) Mycobacterium tuberculosis catalase and peroxidase activities and resistance to oxidative killing in human monocytes in vitro. Infect Immun 67: 74-9 PubMed GONUTS page
- ↑ Wengenack NL et al. (1999) Mycobacterium tuberculosis KatG is a peroxynitritase. Biochem Biophys Res Commun 256: 485-7 PubMed GONUTS page
- ↑ 10.0 10.1 Bertrand T et al. (2004) Crystal structure of Mycobacterium tuberculosis catalase-peroxidase. J Biol Chem 279: 38991-9 PubMed GONUTS page
- ↑ Mulder MA et al. (1999) Involvement of the N- and C-terminal domains of Mycobacterium tuberculosis KatG in the protection of mutant Escherichia coli against DNA-damaging agents. Microbiology 145 ( Pt 8): 2011-21 PubMed GONUTS page
