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MYCS2:LIGD
Contents
| Species (Taxon ID) | Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155). (246196) | |
| Gene Name(s) | ligD | |
| Protein Name(s) | Multifunctional non-homologous end joining protein LigD
NHEJ DNA polymerase DNA repair polymerase Pol Polymerase/primase 3'-phosphoesterase 3'-ribonuclease/3'-phosphatase PE DNA ligase Lig Polydeoxyribonucleotide synthase [ATP] | |
| External Links | ||
| UniProt | A0R3R7 | |
| EMBL | CP000480 CP001663 | |
| RefSeq | WP_014878386.1 YP_006570155.1 YP_889805.1 | |
| STRING | 246196.MSMEG_5570 | |
| EnsemblBacteria | ABK75957 | |
| GeneID | 4535131 | |
| KEGG | msm:MSMEG_5570 | |
| PATRIC | 18083411 | |
| eggNOG | COG3285 | |
| HOGENOM | HOG000222509 | |
| KO | K01971 | |
| OrthoDB | EOG661H49 | |
| BioCyc | MSME246196:GJ4Y-5569-MONOMER | |
| Proteomes | UP000000757 UP000006158 | |
| GO | GO:0005524 GO:0003677 GO:0003910 GO:0003896 GO:0003887 GO:0004527 GO:0046872 GO:0006310 GO:0006303 GO:0016032 | |
| Gene3D | 2.40.50.140 | |
| InterPro | IPR012309 IPR012310 IPR014146 IPR002755 IPR014144 IPR014145 IPR012340 | |
| Pfam | PF04679 PF01068 PF01896 PF13298 | |
| SUPFAM | SSF50249 | |
| TIGRFAMs | TIGR02777 TIGR02778 TIGR02779 | |
| PROSITE | PS50160 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0006303 |
double-strand break repair via nonhomologous end joining |
ECO:0000353 |
physical interaction evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006303 |
double-strand break repair via nonhomologous end joining |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006266 |
DNA ligation |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0003910 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006266 |
DNA ligation |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0003910 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0071897 |
DNA biosynthetic process |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0003887 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0090305 |
nucleic acid phosphodiester bond hydrolysis |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004527 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0090305 |
nucleic acid phosphodiester bond hydrolysis |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004518 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003910 |
DNA ligase (ATP) activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006281 |
DNA repair |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006310 |
DNA recombination |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003910 |
DNA ligase (ATP) activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006310 |
DNA recombination |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004518 |
nuclease activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003824 |
catalytic activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006974 |
cellular response to DNA damage stimulus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016779 |
nucleotidyltransferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006281 |
DNA repair |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008152 |
metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016874 |
ligase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004527 |
exonuclease activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016032 |
viral process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003887 |
DNA-directed DNA polymerase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Li, Z et al. (2011) A Sir2-like protein participates in mycobacterial NHEJ. PLoS ONE 6 e20045 PubMed GONUTS page
- ↑ Gong, C et al. (2005) Mechanism of nonhomologous end-joining in mycobacteria: a low-fidelity repair system driven by Ku, ligase D and ligase C. Nat. Struct. Mol. Biol. 12 304-12 PubMed GONUTS page
b
d
- GO:0003887 ! DNA-directed DNA polymerase activity
- GO:0003677 ! DNA binding
- GO:0071897 ! DNA biosynthetic process
- GO:0006974 ! DNA damage response
- GO:0003910 ! DNA ligase (ATP) activity
- GO:0006266 ! DNA ligation
- GO:0006310 ! DNA recombination
- GO:0006281 ! DNA repair
- GO:0006303 ! double-strand break repair via nonhomologous end joining
m
n
