Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

MOUSE:WLS

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Mus musculus (Mouse). (taxon:10090)
Gene Name(s) Wls ( synonyms: Gpr177 )
Protein Name(s)
  • Protein wntless homolog
  • Integral membrane protein GPR177
  • Protein evenness interrupted homolog
  • EVI
External Links
UniProt Identifier WLS_MOUSE
UniProt Accessions Q6DID7, Q8CE42, Q9D2B7,
EMBL AK019886, AK029053, AK029104, AK044810, AK049842, AK077407, AK159207, BC075615, BC018381,
RefSeq NP_080858.3,
Ensembl ENSMUST00000068952,

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0007275

multicellular organismal development

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0217

P

GO:0016020

membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

GO:0016021

integral to membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

GO:0017147

Wnt-protein binding

PMID:19841259[1]

IDA: Inferred from Direct Assay

F

GO:0005515

protein binding

PMID:19841259[1]

IPI: Inferred from Physical Interaction

UniProtKB:P17553

F

GO:0030659

cytoplasmic vesicle membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0089

C

GO:0016055

Wnt receptor signaling pathway

PMID:19841259[1]

IMP: Inferred from Mutant Phenotype

P

GO:0000139

Golgi membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0134

C

GO:0001707

mesoderm formation

PMID:19841259[1]

IMP: Inferred from Mutant Phenotype

P

GO:0009948

anterior/posterior axis specification

PMID:19841259[1]

IMP: Inferred from Mutant Phenotype

P

GO:0016055

Wnt receptor signaling pathway

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0879

P

GO:0031410

cytoplasmic vesicle

PMID:19841259[1]

IDA: Inferred from Direct Assay

C

GO:0005515

protein binding

PMID:19841259[1]

IPI: Inferred from Physical Interaction

UniProtKB:P04426

F

GO:0005794

Golgi apparatus

PMID:19841259[1]

IDA: Inferred from Direct Assay

C

GO:0005515

protein binding

PMID:19841259[1]

IPI: Inferred from Physical Interaction

UniProtKB:P22725

F

GO:0031410

cytoplasmic vesicle

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0968

C

GO:0005794

Golgi apparatus

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0333

C

Contributes to

GO:0022002

negative regulation of anterior neural cell fate commitment of the neural plate by Wnt receptor signaling pathway

PMID:21226062[2]

IMP: Inferred from Mutant Phenotype

P

Figure 4- By inactivating gene Gpr177, neural development guided by the Wnt receptor is distorted and made abnormal.

complete

GO:0000139

Golgi membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0134

C

GO:0001707

mesoderm formation

PMID:19841259[1]

IMP: Inferred from Mutant Phenotype

P

GO:0005515

protein binding

PMID:19841259[1]

IPI: Inferred from Physical Interaction

UniProtKB:P04426

F

GO:0005515

protein binding

PMID:19841259[1]

IPI: Inferred from Physical Interaction

UniProtKB:P17553

F

GO:0005515

protein binding

PMID:19841259[1]

IPI: Inferred from Physical Interaction

UniProtKB:P22725

F

GO:0005794

Golgi apparatus

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0333

C

GO:0005794

Golgi apparatus

PMID:19841259[1]

IDA: Inferred from Direct Assay

C

GO:0007275

multicellular organismal development

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0217

P

GO:0009948

anterior/posterior axis specification

PMID:19841259[1]

IMP: Inferred from Mutant Phenotype

P

GO:0016020

membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

GO:0016021

integral to membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

GO:0016055

Wnt receptor signaling pathway

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0879

P

GO:0016055

Wnt receptor signaling pathway

PMID:19841259[1]

IMP: Inferred from Mutant Phenotype

P

GO:0017147

Wnt-protein binding

PMID:19841259[1]

IDA: Inferred from Direct Assay

F

GO:0030659

cytoplasmic vesicle membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0089

C

GO:0031410

cytoplasmic vesicle

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0968

C

GO:0031410

cytoplasmic vesicle

PMID:19841259[1]

IDA: Inferred from Direct Assay

C


Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 1.15 1.16 1.17 Fu J et al. (2009) Reciprocal regulation of Wnt and Gpr177/mouse Wntless is required for embryonic axis formation. Proc Natl Acad Sci U S A 106: 18598-603 PubMed GONUTS page
  2. Fu J et al. (2011) Gpr177/mouse Wntless is essential for Wnt-mediated craniofacial and brain development. Dev Dyn PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox