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MOUSE:SOX3
Contents |
| Species (Taxon ID) | Mus musculus (Mouse). ([1]) | |
| Gene Name(s) | Sox3 (synonyms: Sox-3) | |
| Protein Name(s) | Transcription factor SOX-3 | |
| External Links | ||
| EMBL | X94125 AF434675 AB108674 | |
| IPI | IPI00986516 | |
| PIR | S10948 | |
| UniGene | Mm.35784 | |
| ProteinModelPortal | P53784 | |
| SMR | P53784 | |
| STRING | P53784 | |
| PhosphoSite | P53784 | |
| PRIDE | P53784 | |
| Ensembl | ENSMUST00000055041 | |
| MGI | MGI:98365 | |
| eggNOG | maNOG18167 | |
| HOVERGEN | HBG105663 | |
| InParanoid | P53784 | |
| ArrayExpress | P53784 | |
| Bgee | P53784 | |
| CleanEx | MM_SOX3 | |
| Genevestigator | P53784 | |
| GermOnline | ENSMUSG00000045179 | |
| GO | GO:0005634 GO:0000979 GO:0001106 GO:0060324 GO:0021854 GO:0045665 GO:0009887 GO:0021983 GO:0007423 GO:0060009 GO:0007530 GO:0048515 | |
| InterPro | IPR000910 IPR009071 IPR022097 | |
| Gene3D | G3DSA:1.10.30.10 | |
| Pfam | PF00505 PF12336 | |
| SMART | SM00398 | |
| SUPFAM | SSF47095 | |
| PROSITE | PS50118 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
IDA: Inferred from Direct Assay |
|
P |
Seeded From UniProt |
|||
| GO:0000979 |
RNA polymerase II core promoter sequence-specific DNA binding |
IDA: Inferred from Direct Assay |
|
F |
Seeded From UniProt |
|||
| GO:0001106 |
RNA polymerase II transcription corepressor activity |
IDA: Inferred from Direct Assay |
|
F |
Seeded From UniProt |
|||
| GO:0003677 |
DNA binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0003677 |
DNA binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0003677 |
DNA binding |
IDA: Inferred from Direct Assay |
|
F |
Seeded From UniProt |
|||
| GO:0005634 |
nucleus |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005634 |
nucleus |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0191 |
C |
Seeded From UniProt |
|||
| GO:0006351 |
transcription, DNA-dependent |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006355 |
regulation of transcription, DNA-dependent |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0007275 |
multicellular organismal development |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0007423 |
sensory organ development |
IMP: Inferred from Mutant Phenotype |
|
P |
Seeded From UniProt |
|||
| GO:0007530 |
sex determination |
IMP: Inferred from Mutant Phenotype |
|
P |
Seeded From UniProt |
|||
| GO:0009887 |
organ morphogenesis |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3036671 |
P |
Seeded From UniProt |
|||
| GO:0021854 |
hypothalamus development |
IMP: Inferred from Mutant Phenotype |
|
P |
Seeded From UniProt |
|||
| GO:0021983 |
pituitary gland development |
IMP: Inferred from Mutant Phenotype |
|
P |
Seeded From UniProt |
|||
| GO:0030900 |
forebrain development |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3036671 |
P |
Seeded From UniProt |
|||
| GO:0045665 |
negative regulation of neuron differentiation |
ISS: Inferred from Sequence or Structural Similarity |
P |
Seeded From UniProt |
||||
| GO:0048515 |
spermatid differentiation |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2682663 |
P |
Seeded From UniProt |
|||
| GO:0060009 |
Sertoli cell development |
IEP: Inferred from Expression Pattern |
|
P |
Seeded From UniProt |
|||
| GO:0060324 |
face development |
IMP: Inferred from Mutant Phenotype |
|
P |
Seeded From UniProt |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Shen JH & Ingraham HA (2002) Regulation of the orphan nuclear receptor steroidogenic factor 1 by Sox proteins. Mol Endocrinol 16: 529-40 PubMed GONUTS page
- ↑ Collignon J et al. (1996) A comparison of the properties of Sox-3 with Sry and two related genes, Sox-1 and Sox-2. Development 122: 509-20 PubMed GONUTS page
- ↑ 3.0 3.1 Rizzoti K & Lovell-Badge R (2007) SOX3 activity during pharyngeal segmentation is required for craniofacial morphogenesis. Development 134: 3437-48 PubMed GONUTS page
- ↑ Sutton E et al. (2011) Identification of SOX3 as an XX male sex reversal gene in mice and humans. J Clin Invest 121: 328-41 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 Rizzoti K et al. (2004) SOX3 is required during the formation of the hypothalamo-pituitary axis. Nat Genet 36: 247-55 PubMed GONUTS page
- ↑ Raverot G et al. (2005) Sox3 expression in undifferentiated spermatogonia is required for the progression of spermatogenesis. Dev Biol 283: 215-25 PubMed GONUTS page
