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MOUSE:Q9ESZ3

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Contents

Species (Taxon ID) Mus musculus (Mouse). (taxon:10090)
Gene Name(s) Acacb ( synonyms: ACC2 )
Protein Name(s)
  • Acetyl-CoA carboxylase 280
External Links
UniProt Identifier Q9ESZ3_MOUSE
UniProt Accessions Q9ESZ3, Q9ESZ2,
EMBL AF290178,
RefSeq NP_598665.2,

Annotations

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0005739

mitochondrion

IDA: Inferred from Direct Assay

C

Source: MGI

GO:0003989

acetyl-CoA carboxylase activity

IDA: Inferred from Direct Assay

F

Source: MGI

GO:0005524

ATP binding

IEA: Inferred from Electronic Annotation

F

Source: InterPro

GO:0006633

fatty acid biosynthetic process

IMP: Inferred from Mutant Phenotype

P

Source: MGI

incorrect (CACAO)

GO:0046320

regulation of fatty acid oxidation

PMID:20139635[1]

TAS: Traceable Author Statement

P

intro ACC2 knockout mice represent enhanced β-oxidation, and thus this implies that ACC2 is critical for the regulation of lipolysis

complete

incorrect (CACAO)

GO:0050994

regulation of lipid catabolic process

PMID:20139635[1]

TAS: Traceable Author Statement

P

intro ACC2 knockout mice represent enhanced β-oxidation, and thus this implies that ACC2 is critical for the regulation of lipolysis

complete

GO:0003824

catalytic activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013817

F

GO:0003824

catalytic activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016185

F

GO:0003989

acetyl-CoA carboxylase activity

PMID:17210641[2]

IMP: Inferred from Mutant Phenotype

F

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013817

F

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016185

F

GO:0005737

cytoplasm

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000367079

C

GO:0005739

mitochondrion

PMID:18614015[3]

IDA: Inferred from Direct Assay

C

GO:0005794

Golgi apparatus

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000367079

C

GO:0006633

fatty acid biosynthetic process

PMID:17210641[2]

IMP: Inferred from Mutant Phenotype

P

GO:0008152

metabolic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013817

P

GO:0008152

metabolic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016185

P


Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Zhao LF et al. (2010) Hormonal regulation of acetyl-CoA carboxylase isoenzyme gene transcription. Endocr J 57: 317-24 PubMed GONUTS page
  2. 2.0 2.1 Harada N et al. (2007) Hepatic de novo lipogenesis is present in liver-specific ACC1-deficient mice. Mol Cell Biol 27: 1881-8 PubMed GONUTS page
  3. Pagliarini DJ et al. (2008) A mitochondrial protein compendium elucidates complex I disease biology. Cell 134: 112-23 PubMed GONUTS page
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