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MOUSE:PTPRE

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Contents

Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Ptpre (synonyms: Ptpe)
Protein Name(s) Receptor-type tyrosine-protein phosphatase epsilon

Protein-tyrosine phosphatase epsilon R-PTP-epsilon

External Links
UniProt P49446
EMBL U35368
U36758
U40280
D83484
U62387
AK154910
CH466531
CH466531
Z23052
Z23053
IPI IPI00654319
IPI00954626
IPI00988675
PIR B61180
JC6132
S40284
RefSeq NP_035342.3
UniGene Mm.945
ProteinModelPortal P49446
SMR P49446
IntAct P49446
STRING P49446
PhosphoSite P49446
PRIDE P49446
Ensembl ENSMUST00000054880
ENSMUST00000073961
GeneID 19267
KEGG mmu:19267
UCSC uc009kee.1
uc009kek.1
CTD 5791
MGI MGI:97813
eggNOG roNOG10614
GeneTree ENSGT00590000082937
HOVERGEN HBG053758
InParanoid P49446
OMA IVIDAMI
OrthoDB EOG44BB1S
PhylomeDB P49446
ArrayExpress P49446
Bgee P49446
CleanEx MM_PTPRE
Genevestigator P49446
GermOnline ENSMUSG00000041836
GO GO:0005737
GO:0016021
GO:0005886
GO:0042803
GO:0004725
GO:0046627
GO:0006468
GO:0033003
GO:0007185
InterPro IPR000387
IPR016130
IPR000242
IPR016336
KO K01104
Pfam PF00102
PIRSF PIRSF002006
PRINTS PR00700
SMART SM00194
PROSITE PS00383
PS50056
PS50055

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004721

phosphoprotein phosphatase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0904

F

Seeded From UniProt

GO:0004725

protein tyrosine phosphatase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000242

F

Seeded From UniProt

GO:0004725

protein tyrosine phosphatase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016130

F

Seeded From UniProt

GO:0004725

protein tyrosine phosphatase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016336

F

Seeded From UniProt

GO:0004725

protein tyrosine phosphatase activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:3.1.3.48

F

Seeded From UniProt

GO:0004725

protein tyrosine phosphatase activity

PMID:12861030[1]

IDA: Inferred from Direct Assay

F

Seeded From UniProt

GO:0005737

cytoplasm

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

Seeded From UniProt

GO:0005737

cytoplasm

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0086

C

Seeded From UniProt

GO:0005737

cytoplasm

PMID:18006633[2]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

GO:0005886

plasma membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

Seeded From UniProt

GO:0005886

plasma membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0039

C

Seeded From UniProt

GO:0005886

plasma membrane

PMID:18006633[2]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

GO:0006468

protein phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016336

P

Seeded From UniProt

GO:0006470

protein dephosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000242

P

Seeded From UniProt

GO:0007185

transmembrane receptor protein tyrosine phosphatase signaling pathway

PMID:12861030[1]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

GO:0016020

membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded From UniProt

GO:0016021

integral to membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

Seeded From UniProt

GO:0016311

dephosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000387

P

Seeded From UniProt

GO:0016311

dephosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016130

P

Seeded From UniProt

GO:0016787

hydrolase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0378

F

Seeded From UniProt

GO:0016791

phosphatase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000387

F

Seeded From UniProt

GO:0016791

phosphatase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016130

F

Seeded From UniProt

GO:0033003

regulation of mast cell activation

PMID:19508371[3]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

GO:0035335

peptidyl-tyrosine dephosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000242

P

Seeded From UniProt

GO:0035335

peptidyl-tyrosine dephosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016130

P

Seeded From UniProt

GO:0035335

peptidyl-tyrosine dephosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016336

P

Seeded From UniProt

GO:0035335

peptidyl-tyrosine dephosphorylation

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:3.1.3.48

P

Seeded From UniProt

GO:0035335

peptidyl-tyrosine dephosphorylation

PMID:12861030[1]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

GO:0042803

protein homodimerization activity

PMID:12861030[1]

IDA: Inferred from Direct Assay

F

Seeded From UniProt

GO:0046627

negative regulation of insulin receptor signaling pathway

PMID:18006633[2]

IDA: Inferred from Direct Assay

P

Seeded From UniProt


Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Toledano-Katchalski H et al. (2003) Dimerization in vivo and inhibition of the nonreceptor form of protein tyrosine phosphatase epsilon. Mol Cell Biol 23: 5460-71 PubMed GONUTS page
  2. 2.0 2.1 2.2 Aga-Mizrachi S et al. (2008) Cytosolic protein tyrosine phosphatase-epsilon is a negative regulator of insulin signaling in skeletal muscle. Endocrinology 149: 605-14 PubMed GONUTS page
  3. Akimoto M et al. (2009) Protein tyrosine phosphatase epsilon is a negative regulator of FcepsilonRI-mediated mast cell responses. Scand J Immunol 69: 401-11 PubMed GONUTS page
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