GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
MOUSE:NK1R
Contents |
| Species (Taxon ID) | Mus musculus (Mouse). ([1]) | |
| Gene Name(s) | Tacr1 (synonyms: Tac1r) | |
| Protein Name(s) | Substance-P receptor
SPR NK-1 receptor NK-1R Tachykinin receptor 1 | |
| External Links | ||
| EMBL | X62934 AK038558 CH466523 BC075631 BC098332 L27828 L27826 | |
| IPI | IPI00131251 | |
| PIR | S20304 | |
| UniGene | Mm.8055 | |
| ProteinModelPortal | P30548 | |
| SMR | P30548 | |
| STRING | P30548 | |
| PRIDE | P30548 | |
| Ensembl | ENSMUST00000032122 | |
| CTD | 21336 | |
| MGI | MGI:98475 | |
| eggNOG | roNOG08125 | |
| GeneTree | ENSGT00560000076767 | |
| HOGENOM | HBG443644 | |
| HOVERGEN | HBG103412 | |
| InParanoid | P30548 | |
| OMA | PVDSDLF | |
| OrthoDB | EOG4WQ12N | |
| NextBio | 300500 | |
| ArrayExpress | P30548 | |
| Bgee | P30548 | |
| CleanEx | MM_TACR1 | |
| Genevestigator | P30548 | |
| GermOnline | ENSMUSG00000030043 | |
| GO | GO:0016021 GO:0005886 | |
| InterPro | IPR000276 IPR017452 IPR001681 IPR000046 | |
| Pfam | PF00001 | |
| PRINTS | PR00237 PR01024 PR00244 | |
| PROSITE | PS00237 PS50262 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0002118 |
aggressive behavior |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
P |
Seeded From UniProt |
|||
| GO:0002526 |
acute inflammatory response |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
P |
Seeded From UniProt |
|||
| GO:0004871 |
signal transducer activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004872 |
receptor activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004930 |
G-protein coupled receptor activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004995 |
tachykinin receptor activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004995 |
tachykinin receptor activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
C |
Seeded From UniProt |
|||
| GO:0005886 |
plasma membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005886 |
plasma membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005886 |
plasma membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005886 |
plasma membrane |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000303522 |
C |
Seeded From UniProt |
|||
| GO:0005886 |
plasma membrane |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0039 |
C |
Seeded From UniProt |
|||
| GO:0006950 |
response to stress |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
P |
Seeded From UniProt |
|||
| GO:0007165 |
signal transduction |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0007186 |
G-protein coupled receptor protein signaling pathway |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0007186 |
G-protein coupled receptor protein signaling pathway |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0007186 |
G-protein coupled receptor protein signaling pathway |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0007186 |
G-protein coupled receptor protein signaling pathway |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0007204 |
elevation of cytosolic calcium ion concentration |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
P |
Seeded From UniProt |
|||
| GO:0007217 |
tachykinin receptor signaling pathway |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000303522 |
P |
Seeded From UniProt |
|||
| GO:0007616 |
long-term memory |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
P |
Seeded From UniProt |
|||
| GO:0008217 |
regulation of blood pressure |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
P |
Seeded From UniProt |
|||
| GO:0008306 |
associative learning |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
P |
Seeded From UniProt |
|||
| GO:0009408 |
response to heat |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
P |
Seeded From UniProt |
|||
| GO:0009725 |
response to hormone stimulus |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
P |
Seeded From UniProt |
|||
| GO:0009986 |
cell surface |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
C |
Seeded From UniProt |
|||
| GO:0010193 |
response to ozone |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
P |
Seeded From UniProt |
|||
| GO:0010634 |
positive regulation of epithelial cell migration |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
P |
Seeded From UniProt |
|||
| GO:0010996 |
response to auditory stimulus |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
P |
Seeded From UniProt |
|||
| GO:0014070 |
response to organic cyclic compound |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
P |
Seeded From UniProt |
|||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0016021 |
integral to membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0016021 |
integral to membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0016021 |
integral to membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0016021 |
integral to membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0016496 |
substance P receptor activity |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
F |
Seeded From UniProt |
|||
| GO:0019233 |
sensory perception of pain |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
P |
Seeded From UniProt |
|||
| GO:0030425 |
dendrite |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
C |
Seeded From UniProt |
|||
| GO:0032224 |
positive regulation of synaptic transmission, cholinergic |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
P |
Seeded From UniProt |
|||
| GO:0032230 |
positive regulation of synaptic transmission, GABAergic |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
P |
Seeded From UniProt |
|||
| GO:0035094 |
response to nicotine |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
P |
Seeded From UniProt |
|||
| GO:0035106 |
operant conditioning |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
P |
Seeded From UniProt |
|||
| GO:0035815 |
positive regulation of renal sodium excretion |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
P |
Seeded From UniProt |
|||
| GO:0042713 |
sperm ejaculation |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
P |
Seeded From UniProt |
|||
| GO:0042755 |
eating behavior |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
P |
Seeded From UniProt |
|||
| GO:0043278 |
response to morphine |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
P |
Seeded From UniProt |
|||
| GO:0045471 |
response to ethanol |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
P |
Seeded From UniProt |
|||
| GO:0045760 |
positive regulation of action potential |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
P |
Seeded From UniProt |
|||
| GO:0045777 |
positive regulation of blood pressure |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
P |
Seeded From UniProt |
|||
| GO:0045907 |
positive regulation of vasoconstriction |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
P |
Seeded From UniProt |
|||
| GO:0048265 |
response to pain |
IMP: Inferred from Mutant Phenotype |
|
P |
Seeded From UniProt |
|||
| GO:0048266 |
behavioral response to pain |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
P |
Seeded From UniProt |
|||
| GO:0050671 |
positive regulation of lymphocyte proliferation |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
P |
Seeded From UniProt |
|||
| GO:0050679 |
positive regulation of epithelial cell proliferation |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
P |
Seeded From UniProt |
|||
| GO:0051496 |
positive regulation of stress fiber assembly |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
P |
Seeded From UniProt |
|||
| GO:0060083 |
smooth muscle contraction involved in micturition |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
P |
Seeded From UniProt |
|||
| GO:0070474 |
positive regulation of uterine smooth muscle contraction |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000007984 |
P |
Seeded From UniProt |
|||
| GO:0071944 |
cell periphery |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0070472 |
positive regulation of uterine smooth muscle contraction |
IDA: Inferred from Direct Assay |
P |
from figure 1 increasing amounts of NK1 were added to the uterine preparation prior to testing. Contractile force produced by the longitudinally oriented smooth muscle fibers was recorded by a Grass FT03 force transducer connected to a MacLab data acquisition system. Uterine preparations treated with larger amounts of NK1 displayed increased levels of contraction. |
complete | |||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Jasmin L et al. (2002) The NK1 receptor mediates both the hyperalgesia and the resistance to morphine in mice lacking noradrenaline. Proc Natl Acad Sci U S A 99: 1029-34 PubMed GONUTS page
- ↑ Liu HL et al. (2002) Immunocytochemical localization of substance P receptor in hypothalamic oxytocin-containing neurons of C57 mice. Brain Res 948: 175-9 PubMed GONUTS page
- ↑ Patak E et al. (2005) Functional and molecular characterization of tachykinins and tachykinin receptors in the mouse uterus. Biol Reprod 72: 1125-33 PubMed GONUTS page
