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MOUSE:MET

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Contents

Species (Taxon ID) Mus musculus (Mouse). ([1])
Gene Name(s) Met
Protein Name(s) Hepatocyte growth factor receptor

HGF receptor HGF/SF receptor Proto-oncogene c-Met Scatter factor receptor SF receptor Tyrosine-protein kinase Met

External Links
EMBL Y00671
M33424
IPI IPI00130420
PIR S01254
UniGene Mm.86844
ProteinModelPortal P16056
SMR P16056
IntAct P16056
MINT MINT-137318
STRING P16056
PhosphoSite P16056
PRIDE P16056
MGI MGI:96969
HOGENOM HBG445765
HOVERGEN HBG006348
InParanoid P16056
OrthoDB EOG466VK2
BRENDA 2.7.10.1
PMAP-CutDB P16056
ArrayExpress P16056
Bgee P16056
CleanEx MM_MET
Genevestigator P16056
GermOnline ENSMUSG00000009376
GO GO:0016021
GO:0005524
GO:0005515
GO:0004714
GO:0007275
GO:0007169
InterPro IPR013783
IPR014756
IPR002909
IPR011009
IPR003659
IPR016201
IPR002165
IPR000719
IPR017441
IPR001627
IPR001245
IPR008266
IPR020635
IPR016244
IPR015943
Gene3D G3DSA:2.60.40.10
G3DSA:2.130.10.10
Pfam PF07714
PF01437
PF01403
PF01833
PIRSF PIRSF000617
PRINTS PR00109
SMART SM00429
SM00423
SM00630
SM00219
SUPFAM SSF81296
SSF56112
SSF103575
SSF101912
PROSITE PS00107
PS50011
PS00109
PS51004

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0547

F

Seeded From UniProt

GO:0004672

protein kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719

F

Seeded From UniProt

GO:0004672

protein kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001245

F

Seeded From UniProt

GO:0004713

protein tyrosine kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR008266

F

Seeded From UniProt

GO:0004713

protein tyrosine kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR020635

F

Seeded From UniProt

GO:0004713

protein tyrosine kinase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0829

F

Seeded From UniProt

GO:0004714

transmembrane receptor protein tyrosine kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016244

F

Seeded From UniProt

GO:0004714

transmembrane receptor protein tyrosine kinase activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:2.7.10.1

F

Seeded From UniProt

GO:0004872

receptor activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016201

F

Seeded From UniProt

GO:0004872

receptor activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0675

F

Seeded From UniProt

GO:0005515

protein binding

PMID:18585357[1]

IPI: Inferred from Physical Interaction

UniProtKB:P14210

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016244

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017441

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0067

F

Seeded From UniProt

GO:0006468

protein phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719

P

Seeded From UniProt

GO:0006468

protein phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001245

P

Seeded From UniProt

GO:0006468

protein phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR008266

P

Seeded From UniProt

GO:0006468

protein phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016244

P

Seeded From UniProt

GO:0007169

transmembrane receptor protein tyrosine kinase signaling pathway

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016244

P

Seeded From UniProt

GO:0007275

multicellular organismal development

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016201

P

Seeded From UniProt

GO:0016020

membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002165

C

Seeded From UniProt

GO:0016020

membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016201

C

Seeded From UniProt

GO:0016020

membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded From UniProt

GO:0016020

membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0162

C

Seeded From UniProt

GO:0016021

integral to membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016244

C

Seeded From UniProt

GO:0016021

integral to membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

Seeded From UniProt

GO:0016301

kinase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0418

F

Seeded From UniProt

GO:0016310

phosphorylation

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0418

P

Seeded From UniProt

GO:0016740

transferase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0808

F

Seeded From UniProt

GO:0016772

transferase activity, transferring phosphorus-containing groups

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011009

F

Seeded From UniProt

GO:0007268

synaptic transmission

PMID:21490227[2]

IMP: Inferred from Mutant Phenotype

P

Figure 3F, G showed that KO Met mice had a higher synaptic strength input (amplitude) from layer 2/3 to corticostriatal neurons compared to wild type.

complete

GO:0060079

regulation of excitatory postsynaptic membrane potential

PMID:21490227[2]

IMP: Inferred from Mutant Phenotype

P

Figure 5D, shows that knockout Met mice had greater strength in unitary EPSC than wild type, by a factor of 1.4.

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Ly A et al. (2008) DSCAM is a netrin receptor that collaborates with DCC in mediating turning responses to netrin-1. Cell 133: 1241-54 PubMed GONUTS page
  2. 2.0 2.1 Qiu S et al. (2011) Circuit-specific intracortical hyperconnectivity in mice with deletion of the autism-associated Met receptor tyrosine kinase. J Neurosci 31: 5855-64 PubMed GONUTS page
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