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MOUSE:MET
Contents |
| Species (Taxon ID) | Mus musculus (Mouse). ([1]) | |
| Gene Name(s) | Met | |
| Protein Name(s) | Hepatocyte growth factor receptor
HGF receptor HGF/SF receptor Proto-oncogene c-Met Scatter factor receptor SF receptor Tyrosine-protein kinase Met | |
| External Links | ||
| EMBL | Y00671 M33424 | |
| IPI | IPI00130420 | |
| PIR | S01254 | |
| UniGene | Mm.86844 | |
| ProteinModelPortal | P16056 | |
| SMR | P16056 | |
| IntAct | P16056 | |
| MINT | MINT-137318 | |
| STRING | P16056 | |
| PhosphoSite | P16056 | |
| PRIDE | P16056 | |
| MGI | MGI:96969 | |
| HOGENOM | HBG445765 | |
| HOVERGEN | HBG006348 | |
| InParanoid | P16056 | |
| OrthoDB | EOG466VK2 | |
| BRENDA | 2.7.10.1 | |
| PMAP-CutDB | P16056 | |
| ArrayExpress | P16056 | |
| Bgee | P16056 | |
| CleanEx | MM_MET | |
| Genevestigator | P16056 | |
| GermOnline | ENSMUSG00000009376 | |
| GO | GO:0016021 GO:0005524 GO:0005515 GO:0004714 GO:0007275 GO:0007169 | |
| InterPro | IPR013783 IPR014756 IPR002909 IPR011009 IPR003659 IPR016201 IPR002165 IPR000719 IPR017441 IPR001627 IPR001245 IPR008266 IPR020635 IPR016244 IPR015943 | |
| Gene3D | G3DSA:2.60.40.10 G3DSA:2.130.10.10 | |
| Pfam | PF07714 PF01437 PF01403 PF01833 | |
| PIRSF | PIRSF000617 | |
| PRINTS | PR00109 | |
| SMART | SM00429 SM00423 SM00630 SM00219 | |
| SUPFAM | SSF81296 SSF56112 SSF103575 SSF101912 | |
| PROSITE | PS00107 PS50011 PS00109 PS51004 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004672 |
protein kinase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004672 |
protein kinase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004713 |
protein tyrosine kinase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004713 |
protein tyrosine kinase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004713 |
protein tyrosine kinase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004714 |
transmembrane receptor protein tyrosine kinase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004714 |
transmembrane receptor protein tyrosine kinase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004872 |
receptor activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004872 |
receptor activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded From UniProt |
||||
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0006468 |
protein phosphorylation |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006468 |
protein phosphorylation |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006468 |
protein phosphorylation |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006468 |
protein phosphorylation |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0007275 |
multicellular organismal development |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0162 |
C |
Seeded From UniProt |
|||
| GO:0016021 |
integral to membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0016021 |
integral to membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0016301 |
kinase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0016310 |
phosphorylation |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0016740 |
transferase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0016772 |
transferase activity, transferring phosphorus-containing groups |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0007268 |
synaptic transmission |
IMP: Inferred from Mutant Phenotype |
P |
Figure 3F, G showed that KO Met mice had a higher synaptic strength input (amplitude) from layer 2/3 to corticostriatal neurons compared to wild type. |
complete | |||
| GO:0060079 |
regulation of excitatory postsynaptic membrane potential |
IMP: Inferred from Mutant Phenotype |
P |
Figure 5D, shows that knockout Met mice had greater strength in unitary EPSC than wild type, by a factor of 1.4. |
complete | |||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Ly A et al. (2008) DSCAM is a netrin receptor that collaborates with DCC in mediating turning responses to netrin-1. Cell 133: 1241-54 PubMed GONUTS page
- ↑ 2.0 2.1 Qiu S et al. (2011) Circuit-specific intracortical hyperconnectivity in mice with deletion of the autism-associated Met receptor tyrosine kinase. J Neurosci 31: 5855-64 PubMed GONUTS page