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MOUSE:MDR1

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Contents

Species (Taxon ID) Mus musculus (Mouse). ([1])
Gene Name(s) Abcb1 (synonyms: Abcb1b, Mdr1, Mdr1b, Pgy1, Pgy1-1)
Protein Name(s) Multidrug resistance protein 1

ATP-binding cassette sub-family B member 1 P-glycoprotein 1

External Links
EMBL M14757
M60348
IPI IPI00128152
PIR A33719
RefSeq NP_035205.1
UniGene Mm.146649
Mm.389059
ProteinModelPortal P06795
SMR P06795
STRING P06795
PRIDE P06795
Ensembl ENSMUST00000009058
GeneID 18669
KEGG mmu:18669
CTD 18669
MGI MGI:97568
eggNOG roNOG07605
HOGENOM HBG758042
HOVERGEN HBG080809
InParanoid P06795
OMA GMFRYAD
OrthoDB EOG42FSGR
PhylomeDB P06795
NextBio 294678
ArrayExpress P06795
Bgee P06795
Genevestigator P06795
GermOnline ENSMUSG00000028970
GO GO:0016021
GO:0046581
GO:0005739
GO:0005524
GO:0008559
InterPro IPR003439
IPR017871
IPR017940
IPR001140
IPR011527
IPR003593
Pfam PF00664
PF00005
SMART SM00382
SUPFAM SSF90123
PROSITE PS50929
PS00211
PS50893

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000139

Golgi membrane

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000049952

C

Seeded From UniProt

GO:0000139

Golgi membrane

GO_REF:0000033

PANTHER:PTHR24221

C

Seeded From UniProt

GO:0000166

nucleotide binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003593

F

Seeded From UniProt

GO:0000166

nucleotide binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0547

F

Seeded From UniProt

GO:0001666

response to hypoxia

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000049952

P

Seeded From UniProt

GO:0005215

transporter activity

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000049952

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001140

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003439

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011527

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017871

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0067

F

Seeded From UniProt

GO:0005739

mitochondrion

PMID:18614015[1]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

GO:0006200

ATP catabolic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003439

P

Seeded From UniProt

GO:0006200

ATP catabolic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017871

P

Seeded From UniProt

GO:0006810

transport

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001140

P

Seeded From UniProt

GO:0006810

transport

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011527

P

Seeded From UniProt

GO:0006810

transport

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0813

P

Seeded From UniProt

GO:0006810

transport

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000049952

P

Seeded From UniProt

GO:0006855

drug transmembrane transport

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000049952

P

Seeded From UniProt

GO:0007595

lactation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000049952

P

Seeded From UniProt

GO:0008559

xenobiotic-transporting ATPase activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:3.6.3.44

F

Seeded From UniProt

GO:0010212

response to ionizing radiation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000049952

P

Seeded From UniProt

GO:0014045

establishment of endothelial blood-brain barrier

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000049952

P

Seeded From UniProt

GO:0014070

response to organic cyclic compound

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000049952

P

Seeded From UniProt

GO:0015238

drug transmembrane transporter activity

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000049952

F

Seeded From UniProt

GO:0015893

drug transport

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000049952

P

Seeded From UniProt

GO:0016020

membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded From UniProt

GO:0016020

membrane

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000049952

C

Seeded From UniProt

GO:0016020

membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0162

C

Seeded From UniProt

GO:0016021

integral to membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001140

C

Seeded From UniProt

GO:0016021

integral to membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011527

C

Seeded From UniProt

GO:0016021

integral to membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

Seeded From UniProt

GO:0016021

integral to membrane

GO_REF:0000033

PANTHER:PTHR24221

C

Seeded From UniProt

GO:0016324

apical plasma membrane

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000049952

C

Seeded From UniProt

GO:0016324

apical plasma membrane

GO_REF:0000033

PANTHER:PTHR24221

C

Seeded From UniProt

GO:0016787

hydrolase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0378

F

Seeded From UniProt

GO:0016887

ATPase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003439

F

Seeded From UniProt

GO:0016887

ATPase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017871

F

Seeded From UniProt

GO:0017111

nucleoside-triphosphatase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003593

F

Seeded From UniProt

GO:0042493

response to drug

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000049952

P

Seeded From UniProt

GO:0042626

ATPase activity, coupled to transmembrane movement of substances

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001140

F

Seeded From UniProt

GO:0042626

ATPase activity, coupled to transmembrane movement of substances

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011527

F

Seeded From UniProt

GO:0042626

ATPase activity, coupled to transmembrane movement of substances

GO_REF:0000033

PANTHER:PTHR24221

F

Seeded From UniProt

GO:0046581

intercellular canaliculus

PMID:12068294[2]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

GO:0046685

response to arsenic-containing substance

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000049952

P

Seeded From UniProt

GO:0055085

transmembrane transport

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001140

P

Seeded From UniProt

GO:0055085

transmembrane transport

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011527

P

Seeded From UniProt

GO:0055085

transmembrane transport

GO_REF:0000033

PANTHER:PTHR24221

P

Seeded From UniProt

GO:0071356

cellular response to tumor necrosis factor

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000049952

P

Seeded From UniProt


Notes

References

See Help:References for how to manage references in GONUTS.

  1. Pagliarini DJ et al. (2008) A mitochondrial protein compendium elucidates complex I disease biology. Cell 134: 112-23 PubMed GONUTS page
  2. Kikuchi S et al. (2002) Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranes. Nat Genet 31: 320-5 PubMed GONUTS page
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