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MOUSE:HMX3
Contents |
| Species (Taxon ID) | Mus musculus (Mouse). ([1]) | |
| Gene Name(s) | Hmx3 (synonyms: Nkx-5.1, Nkx5-1) | |
| Protein Name(s) | Homeobox protein HMX3
Homeobox protein H6 family member 3 Homeobox protein Nkx-5.1 | |
| External Links | ||
| EMBL | X75330 AJ009935 CH466531 BC139482 BC139483 | |
| IPI | IPI00117494 | |
| PIR | I48690 | |
| RefSeq | NP_032283.3 | |
| UniGene | Mm.323562 | |
| ProteinModelPortal | P42581 | |
| SMR | P42581 | |
| STRING | P42581 | |
| PRIDE | P42581 | |
| Ensembl | ENSMUST00000046093 | |
| GeneID | 15373 | |
| KEGG | mmu:15373 | |
| MGI | MGI:107160 | |
| HOGENOM | HBG714257 | |
| HOVERGEN | HBG098273 | |
| InParanoid | P42581 | |
| PhylomeDB | B9EIJ0 | |
| ArrayExpress | P42581 | |
| Bgee | P42581 | |
| CleanEx | MM_HMX3 | |
| Genevestigator | P42581 | |
| GO | GO:0005634 GO:0043565 GO:0003700 GO:0007420 GO:0030154 GO:0007566 GO:0042472 GO:0060135 GO:0050885 | |
| InterPro | IPR001356 IPR017970 IPR020479 IPR009057 IPR012287 | |
| Gene3D | G3DSA:1.10.10.60 | |
| KO | K09349 | |
| Pfam | PF00046 | |
| PRINTS | PR00024 | |
| SMART | SM00389 | |
| SUPFAM | SSF46689 | |
| PROSITE | PS00027 PS50071 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003677 |
DNA binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0003677 |
DNA binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0003677 |
DNA binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005634 |
nucleus |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005634 |
nucleus |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005634 |
nucleus |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0191 |
C |
Seeded From UniProt |
|||
| GO:0006351 |
transcription, DNA-dependent |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006355 |
regulation of transcription, DNA-dependent |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006355 |
regulation of transcription, DNA-dependent |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006355 |
regulation of transcription, DNA-dependent |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006355 |
regulation of transcription, DNA-dependent |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0007275 |
multicellular organismal development |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0007399 |
nervous system development |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0007420 |
brain development |
IGI: Inferred from Genetic Interaction |
MGI:MGI:107159 |
P |
Seeded From UniProt |
|||
| GO:0007566 |
embryo implantation |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857577 |
P |
Seeded From UniProt |
|||
| GO:0030154 |
cell differentiation |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0042472 |
inner ear morphogenesis |
IGI: Inferred from Genetic Interaction |
MGI:MGI:107159 |
P |
Seeded From UniProt |
|||
| GO:0042472 |
inner ear morphogenesis |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857577 |
P |
Seeded From UniProt |
|||
| GO:0043565 |
sequence-specific DNA binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0043565 |
sequence-specific DNA binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0043565 |
sequence-specific DNA binding |
IDA: Inferred from Direct Assay |
|
F |
Seeded From UniProt |
|||
| GO:0050885 |
neuromuscular process controlling balance |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857577 |
P |
Seeded From UniProt |
|||
| GO:0060135 |
maternal process involved in female pregnancy |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857577 |
P |
Seeded From UniProt |
|||
| GO:0043583 |
ear development |
IMP: Inferred from Mutant Phenotype |
P |
Figure 2. Defects in the inner and middle ear in Six1-deficient mice. |
complete | |||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Wang W et al. (2004) Hmx2 and Hmx3 homeobox genes direct development of the murine inner ear and hypothalamus and can be functionally replaced by Drosophila Hmx. Dev Cell 7: 439-53 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Wang W et al. (1998) Inner ear and maternal reproductive defects in mice lacking the Hmx3 homeobox gene. Development 125: 621-34 PubMed GONUTS page
- ↑ Amendt BA et al. (1999) Transcriptional antagonism between Hmx1 and Nkx2.5 for a shared DNA-binding site. J Biol Chem 274: 11635-42 PubMed GONUTS page
- ↑ Ozaki H et al. (2004) Six1 controls patterning of the mouse otic vesicle. Development 131: 551-62 PubMed GONUTS page
