MOUSE:FGF15

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Fgf15
Protein Name(s)	Fibroblast growth factor 15 FGF-15
External Links
UniProt	O35622
EMBL	AF007268 AK017829 BC021328
CCDS	CCDS22053.1
RefSeq	NP_032029.1
UniGene	Mm.3904
ProteinModelPortal	O35622
SMR	O35622
STRING	10090.ENSMUSP00000033389
PhosphoSite	O35622
PRIDE	O35622
Ensembl	ENSMUST00000033389
GeneID	14170
KEGG	mmu:14170
UCSC	uc009kqr.1
CTD	14170
MGI	MGI:1096383
eggNOG	NOG294039
HOGENOM	HOG000112572
HOVERGEN	HBG051611
InParanoid	O35622
KO	K04358
OMA	SEEDCAF
OrthoDB	EOG7BS4C1
PhylomeDB	O35622
TreeFam	TF335872
Reactome	REACT_196588 REACT_198525 REACT_199063 REACT_206694 REACT_223993 REACT_226341 REACT_230708 REACT_234357 REACT_240139 REACT_94437
NextBio	285330
PRO	PR:O35622
Proteomes	UP000000589
Bgee	O35622
CleanEx	MM_FGF15
ExpressionAtlas	O35622
Genevestigator	O35622
GO	GO:0005576 GO:0008543 GO:0007507 GO:0070858 GO:0001755 GO:0008284 GO:0070374 GO:0046326 GO:0046330
InterPro	IPR008996 IPR028303 IPR002209 IPR028142
PANTHER	PTHR11486 PTHR11486:SF74
PRINTS	PR00262
SMART	SM00442
SUPFAM	SSF50353
PROSITE	PS00247

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0060557	positive regulation of vitamin D biosynthetic process	PMID:24688219	ECO:0000314			P		According to figure 1C, Fgf15 mRNA expression in the ileum was significantly increased in the mice fed the 0.1% Pi diet compared with groups fed the 0.6% or 1.2% Pi diet. Therefore, dietary Pi restriction up-regulates ileal Fgf15 gene expression.	complete CACAO 9815
acts_upstream_of_or_within	GO:0070858	negative regulation of bile acid biosynthetic process	PMID:23747249	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:1928271	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0070858	negative regulation of bile acid biosynthetic process	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O95750	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0070374	positive regulation of ERK1 and ERK2 cascade	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O95750	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0046330	positive regulation of JNK cascade	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O95750	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0046326	positive regulation of glucose import	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O95750	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0010629	negative regulation of gene expression	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O95750	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0009617	response to bacterium		ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0008543	fibroblast growth factor receptor signaling pathway	GO_REF:0000008	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O95750	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0008284	positive regulation of cell population proliferation	GO_REF:0000008	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O95750	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007507	heart development	PMID:15789410	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3044957	P	results_in_development_of:(EMAPA:16346)	Seeded From UniProt	complete
enables	GO:0005104	fibroblast growth factor receptor binding	GO_REF:0000008	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O95750	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0001934	positive regulation of protein phosphorylation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O95750	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0001755	neural crest cell migration	PMID:15789410	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3044957	P	occurs_in:(EMAPA:16346) results_in_movement_of:(CL:0000333)	Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0008083	P		Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0008083	P		Seeded From UniProt	complete
enables	GO:0005104	fibroblast growth factor receptor binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR028303 InterPro:IPR035444	F		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR028303 InterPro:IPR035444	C		Seeded From UniProt	complete
enables	GO:0008083	growth factor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002209	F		Seeded From UniProt	complete
involved_in	GO:0008543	fibroblast growth factor receptor signaling pathway	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR028303 InterPro:IPR035444	P		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C		Seeded From UniProt	complete
enables	GO:0008083	growth factor activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0339	F		Seeded From UniProt	complete
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