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MOUSE:DTBP1
Contents |
| Species (Taxon ID) | Mus musculus (Mouse). ([1]) | |
| Gene Name(s) | Dtnbp1 (synonyms: Sdy) | |
| Protein Name(s) | Dysbindin
Dysbindin-1 Dystrobrevin-binding protein 1 Hermansky-Pudlak syndrome 7 protein homolog HPS7 protein homolog | |
| External Links | ||
| EMBL | AJ404859 AY265461 AK010924 AK159656 BC018350 BC048682 BC058574 | |
| IPI | IPI00128563 IPI00395220 IPI00816938 | |
| RefSeq | NP_080048.2 | |
| UniGene | Mm.352311 | |
| IntAct | Q91WZ8 | |
| MINT | MINT-197141 | |
| STRING | Q91WZ8 | |
| PhosphoSite | Q91WZ8 | |
| PRIDE | Q91WZ8 | |
| Ensembl | ENSMUST00000072329 ENSMUST00000110128 | |
| GeneID | 94245 | |
| KEGG | mmu:94245 | |
| UCSC | uc007qgw.1 uc007qgx.1 | |
| CTD | 84062 | |
| MGI | MGI:2137586 | |
| eggNOG | roNOG14560 | |
| GeneTree | ENSGT00390000010667 | |
| HOGENOM | HBG716605 | |
| HOVERGEN | HBG051416 | |
| InParanoid | Q91WZ8 | |
| OMA | DMSDQEA | |
| OrthoDB | EOG4FTW21 | |
| NextBio | 352255 | |
| ArrayExpress | Q91WZ8 | |
| Bgee | Q91WZ8 | |
| CleanEx | MM_DTNBP1 | |
| Genevestigator | Q91WZ8 | |
| GermOnline | ENSMUSG00000057531 | |
| GO | GO:0033267 GO:0030054 GO:0005789 GO:0010008 GO:0030426 GO:0033162 GO:0005634 GO:0014069 GO:0045211 GO:0042383 GO:0016528 GO:0030672 GO:0019717 GO:0031532 GO:0007596 GO:0007517 GO:0048812 GO:0060155 GO:0060159 | |
| InterPro | IPR007531 | |
| PANTHER | PTHR16294 | |
| Pfam | PF04440 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded From UniProt |
||||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded From UniProt |
||||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded From UniProt |
||||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded From UniProt |
||||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded From UniProt |
||||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded From UniProt |
||||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded From UniProt |
||||
| GO:0005634 |
nucleus |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005634 |
nucleus |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000341680 |
C |
Seeded From UniProt |
|||
| GO:0005634 |
nucleus |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0191 |
C |
Seeded From UniProt |
|||
| GO:0005634 |
nucleus |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000341680 |
C |
Seeded From UniProt |
|||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0086 |
C |
Seeded From UniProt |
|||
| GO:0005737 |
cytoplasm |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0005768 |
endosome |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005783 |
endoplasmic reticulum |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005783 |
endoplasmic reticulum |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0095 |
C |
Seeded From UniProt |
|||
| GO:0005789 |
endoplasmic reticulum membrane |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0005886 |
plasma membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005886 |
plasma membrane |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0006996 |
organelle organization |
IPI: Inferred from Physical Interaction |
P |
Seeded From UniProt |
||||
| GO:0006996 |
organelle organization |
IPI: Inferred from Physical Interaction |
P |
Seeded From UniProt |
||||
| GO:0007517 |
muscle organ development |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0007596 |
blood coagulation |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856628 |
P |
Seeded From UniProt |
|||
| GO:0010008 |
endosome membrane |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0100 |
C |
Seeded From UniProt |
|||
| GO:0014069 |
postsynaptic density |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000341680 |
C |
Seeded From UniProt |
|||
| GO:0014069 |
postsynaptic density |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0297 |
C |
Seeded From UniProt |
|||
| GO:0014069 |
postsynaptic density |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0016528 |
sarcoplasm |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0019717 |
synaptosome |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000341680 |
C |
Seeded From UniProt |
|||
| GO:0019717 |
synaptosome |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0030054 |
cell junction |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0030424 |
axon |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0030426 |
growth cone |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0030659 |
cytoplasmic vesicle membrane |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0089 |
C |
Seeded From UniProt |
|||
| GO:0030672 |
synaptic vesicle membrane |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000341680 |
C |
Seeded From UniProt |
|||
| GO:0030672 |
synaptic vesicle membrane |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0260 |
C |
Seeded From UniProt |
|||
| GO:0030672 |
synaptic vesicle membrane |
ISS: Inferred from Sequence or Structural Similarity |
C |
Seeded From UniProt |
||||
| GO:0030672 |
synaptic vesicle membrane |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0031083 |
BLOC-1 complex |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000341680 |
C |
Seeded From UniProt |
|||
| GO:0031175 |
neuron projection development |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000341680 |
P |
Seeded From UniProt |
|||
| GO:0031175 |
neuron projection development |
ISS: Inferred from Sequence or Structural Similarity |
P |
Seeded From UniProt |
||||
| GO:0031410 |
cytoplasmic vesicle |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0031532 |
actin cytoskeleton reorganization |
IDA: Inferred from Direct Assay |
|
P |
Seeded From UniProt |
|||
| GO:0033162 |
melanosome membrane |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0160 |
C |
Seeded From UniProt |
|||
| GO:0033267 |
axon part |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0042383 |
sarcolemma |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0042802 |
identical protein binding |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000341680 |
F |
Seeded From UniProt |
|||
| GO:0043005 |
neuron projection |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000341680 |
C |
Seeded From UniProt |
|||
| GO:0043005 |
neuron projection |
ISS: Inferred from Sequence or Structural Similarity |
C |
Seeded From UniProt |
||||
| GO:0043197 |
dendritic spine |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0045202 |
synapse |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0045211 |
postsynaptic membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0048812 |
neuron projection morphogenesis |
IDA: Inferred from Direct Assay |
|
P |
Seeded From UniProt |
|||
| GO:0050896 |
response to stimulus |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0060155 |
platelet dense granule organization |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856628 |
P |
Seeded From UniProt |
|||
| GO:0060159 |
regulation of dopamine receptor signaling pathway |
ISS: Inferred from Sequence or Structural Similarity |
P |
Seeded From UniProt |
||||
| GO:0043506 |
regulation of JUN kinase activity |
IMP: Inferred from Mutant Phenotype |
P |
Fig. 3 |
complete | |||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Benson MA et al. (2001) Dysbindin, a novel coiled-coil-containing protein that interacts with the dystrobrevins in muscle and brain. J Biol Chem 276: 24232-41 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Li W et al. (2003) Hermansky-Pudlak syndrome type 7 (HPS-7) results from mutant dysbindin, a member of the biogenesis of lysosome-related organelles complex 1 (BLOC-1). Nat Genet 35: 84-9 PubMed GONUTS page
- ↑ 3.0 3.1 Benson MA et al. (2004) Myospryn is a novel binding partner for dysbindin in muscle. J Biol Chem 279: 10450-8 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 4.8 4.9 Talbot K et al. (2006) Dysbindin-1 is a synaptic and microtubular protein that binds brain snapin. Hum Mol Genet 15: 3041-54 PubMed GONUTS page
- ↑ 5.0 5.1 Swank RT et al. (1991) Sandy: a new mouse model for platelet storage pool deficiency. Genet Res 58: 51-62 PubMed GONUTS page
- ↑ Kubota K et al. (2009) Dysbindin engages in c-Jun N-terminal kinase activity and cytoskeletal organization. Biochem Biophys Res Commun 379: 191-5 PubMed GONUTS page
