MOUSE:CD4

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Species (Taxon ID)	Mus musculus (Mouse). (taxon:10090)
Gene Name(s)	Cd4
Protein Name(s)	T-cell surface glycoprotein CD4 T-cell differentiation antigen L3T4 T-cell surface antigen T4/Leu-3
External Links
UniProt Identifier	CD4_MOUSE
UniProt Accessions	P06332,
EMBL	M36850, M13816, X04836, M36851, M17080, M17078, M17079, AC002397, BC039137,
PIR	A02110,
RefSeq	NP_038516.1,
IntAct	P06332,
Ensembl	ENSMUST00000024044,
Pfam	PF05790, PF09191, PF00047, PF12104,

Annotations

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect
	GO:0001816	cytokine production	PMID:7930593^[1]	IGI: Inferred from Genetic Interaction	MGI:MGI:1891436	P
	GO:0001816	cytokine production	PMID:7930593^[1]	IMP: Inferred from Mutant Phenotype	MGI:MGI:1857281	P
	GO:0001948	glycoprotein binding	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000011653	F
	GO:0005515	protein binding	PMID:7664803^[2]	IPI: Inferred from Physical Interaction	UniProtKB:P06240	F
	GO:0005788	endoplasmic reticulum lumen	PMID:16223484^[3]	IDA: Inferred from Direct Assay		C
	GO:0005789	endoplasmic reticulum membrane	PMID:16223484^[3]	IDA: Inferred from Direct Assay		C
	GO:0005886	plasma membrane	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000011653	C
	GO:0005886	plasma membrane	PMID:14517216^[4]	IDA: Inferred from Direct Assay		C
	GO:0006948	induction by virus of host cell-cell fusion	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000011653	P
	GO:0006955	immune response	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000973	P
	GO:0007155	cell adhesion	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR008424	P
	GO:0007166	cell surface receptor linked signaling pathway	PMID:9208839^[5]	IDA: Inferred from Direct Assay		P
	GO:0008270	zinc ion binding	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000011653	F
	GO:0009897	external side of plasma membrane	PMID:10072077^[6]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:10704459^[7]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:10943842^[8]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:12421911^[9]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:14609575^[10]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:15322158^[11]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:15368291^[12]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:15728238^[13]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:15795238^[14]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:16287714^[15]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:16973387^[16]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:18641307^[17]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:18836449^[18]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:19008373^[19]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:19349303^[20]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:19723499^[21]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:7477352^[22]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:7477353^[23]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:7589135^[24]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:7630421^[25]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:7688139^[26]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:8524870^[27]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:8755570^[28]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:8769481^[29]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:8788039^[30]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:9133426^[31]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:9208839^[5]	IDA: Inferred from Direct Assay		C
	GO:0009986	cell surface	PMID:8612131^[32]	IDA: Inferred from Direct Assay		C
	GO:0016020	membrane	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000973	C
	GO:0016020	membrane	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0472	C
	GO:0016020	membrane	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0162	C
	GO:0016021	integral to membrane	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR008424	C
	GO:0016021	integral to membrane	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0812	C
	GO:0019901	protein kinase binding	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000011653	F
	GO:0019901	protein kinase binding	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSRNOP00000021915	F
	GO:0030217	T cell differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000011653	P
	GO:0030217	T cell differentiation	PMID:1533274^[33]	ISS: Inferred from Sequence or Structural Similarity	UniProtKB:P01730	P
	GO:0032507	maintenance of protein location in cell	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000011653	P
	GO:0042110	T cell activation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSRNOP00000021915	P
	GO:0042803	protein homodimerization activity	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000011653	F
	GO:0045058	T cell selection	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000011653	P
	GO:0045058	T cell selection	PMID:9551897^[34]	ISS: Inferred from Sequence or Structural Similarity	UniProtKB:P01730	P
	GO:0045121	membrane raft	PMID:15128768^[35]	IDA: Inferred from Direct Assay		C
	GO:0045234	protein palmitoleylation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000011653	P
	GO:0045860	positive regulation of protein kinase activity	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000011653	P
	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	PMID:9208839^[5]	IDA: Inferred from Direct Assay		P
	GO:0050850	positive regulation of calcium-mediated signaling	PMID:9208839^[5]	IDA: Inferred from Direct Assay		P
	GO:0050863	regulation of T cell activation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000011653	P
	GO:0050870	positive regulation of T cell activation	PMID:12421911^[9]	IDA: Inferred from Direct Assay		P
	GO:0051789	response to protein stimulus	PMID:15128768^[35]	IDA: Inferred from Direct Assay		P
	GO:0001816	cytokine production	PMID:7930593^[1]	IGI: Inferred from Genetic Interaction	MGI:MGI:1891436	P
	GO:0001816	cytokine production	PMID:7930593^[1]	IMP: Inferred from Mutant Phenotype	MGI:MGI:1857281	P
	GO:0001948	glycoprotein binding	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000011653	F
	GO:0005515	protein binding	PMID:7664803^[2]	IPI: Inferred from Physical Interaction	UniProtKB:P06240	F
	GO:0005769	early endosome	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000011653	C
	GO:0005788	endoplasmic reticulum lumen	PMID:16223484^[3]	IDA: Inferred from Direct Assay		C
	GO:0005789	endoplasmic reticulum membrane	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000011653	C
	GO:0005789	endoplasmic reticulum membrane	PMID:16223484^[3]	IDA: Inferred from Direct Assay		C
	GO:0005886	plasma membrane	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000011653	C
	GO:0005886	plasma membrane	PMID:14517216^[4]	IDA: Inferred from Direct Assay		C
	GO:0006948	induction by virus of host cell-cell fusion	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000011653	P
	GO:0006955	immune response	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000973	P
	GO:0007155	cell adhesion	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR008424	P
	GO:0007166	cell surface receptor linked signaling pathway	PMID:9208839^[5]	IDA: Inferred from Direct Assay		P
	GO:0008270	zinc ion binding	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000011653	F
	GO:0009897	external side of plasma membrane	PMID:10072077^[6]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:10704459^[7]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:10943842^[8]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:12421911^[9]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:14609575^[10]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:15322158^[11]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:15368291^[12]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:15728238^[13]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:15795238^[14]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:16287714^[15]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:16973387^[16]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:18641307^[17]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:18836449^[18]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:19008373^[19]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:19349303^[20]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:19723499^[21]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:7477352^[22]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:7477353^[23]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:7589135^[24]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:7630421^[25]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:7688139^[26]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:8524870^[27]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:8755570^[28]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:8769481^[29]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:8788039^[30]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:9133426^[31]	IDA: Inferred from Direct Assay		C
	GO:0009897	external side of plasma membrane	PMID:9208839^[5]	IDA: Inferred from Direct Assay		C
	GO:0009986	cell surface	PMID:8612131^[32]	IDA: Inferred from Direct Assay		C
	GO:0016020	membrane	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000973	C
	GO:0016020	membrane	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0472	C
	GO:0016020	membrane	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0162	C
	GO:0016021	integral to membrane	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR008424	C
	GO:0016021	integral to membrane	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0812	C
	GO:0019059	initiation of viral infection	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000011653	P
	GO:0019901	protein kinase binding	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000011653	F
	GO:0019901	protein kinase binding	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSRNOP00000021915	F
	GO:0030217	T cell differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000011653	P
	GO:0030217	T cell differentiation	PMID:1533274^[33]	ISS: Inferred from Sequence or Structural Similarity	UniProtKB:P01730	P
	GO:0032507	maintenance of protein location in cell	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000011653	P
	GO:0042110	T cell activation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSRNOP00000021915	P
	GO:0042803	protein homodimerization activity	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000011653	F
	GO:0045058	T cell selection	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000011653	P
	GO:0045058	T cell selection	PMID:9551897^[34]	ISS: Inferred from Sequence or Structural Similarity	UniProtKB:P01730	P
	GO:0045121	membrane raft	PMID:15128768^[35]	IDA: Inferred from Direct Assay		C
	GO:0045234	protein palmitoleylation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000011653	P
	GO:0045860	positive regulation of protein kinase activity	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000011653	P
	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	PMID:9208839^[5]	IDA: Inferred from Direct Assay		P
	GO:0050850	positive regulation of calcium-mediated signaling	PMID:9208839^[5]	IDA: Inferred from Direct Assay		P
	GO:0050863	regulation of T cell activation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000011653	P
	GO:0050870	positive regulation of T cell activation	PMID:12421911^[9]	IDA: Inferred from Direct Assay		P
	GO:0051789	response to protein stimulus	PMID:15128768^[35]	IDA: Inferred from Direct Assay		P
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 Blair PJ et al. (1994) CD4+CD8- T cells are the effector cells in disease pathogenesis in the scurfy (sf) mouse. J Immunol 153: 3764-74 PubMed GONUTS page
↑ ^2.0 ^2.1 Campbell KS et al. (1995) Interactions between the amino-terminal domain of p56lck and cytoplasmic domains of CD4 and CD8 alpha in yeast. Eur J Immunol 25: 2408-12 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 Lidén M et al. (2005) The C-terminal region of cis-retinol/androgen dehydrogenase 1 (CRAD1) confers ER localization and in vivo enzymatic function. Exp Cell Res 311: 205-17 PubMed GONUTS page
↑ ^4.0 ^4.1 Suzuki M et al. (2003) Microtubule-associated [corrected] protein 7 increases the membrane expression of transient receptor potential vanilloid 4 (TRPV4). J Biol Chem 278: 51448-53 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 ^5.3 ^5.4 ^5.5 ^5.6 ^5.7 Wiest DL et al. (1997) A spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte development. Immunity 6: 663-71 PubMed GONUTS page
↑ ^6.0 ^6.1 Moriggl R et al. (1999) Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells. Immunity 10: 249-59 PubMed GONUTS page
↑ ^7.0 ^7.1 Kennedy MK et al. (2000) Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice. J Exp Med 191: 771-80 PubMed GONUTS page
↑ ^8.0 ^8.1 Tamura K et al. (2000) Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis. Cell 102: 221-31 PubMed GONUTS page
↑ ^9.0 ^9.1 ^9.2 ^9.3 Workman CJ et al. (2002) Cutting edge: molecular analysis of the negative regulatory function of lymphocyte activation gene-3. J Immunol 169: 5392-5 PubMed GONUTS page
↑ ^10.0 ^10.1 Matsuzaki J et al. (2003) Successful elimination of memory-type CD8+ T cell subsets by the administration of anti-Gr-1 monoclonal antibody in vivo. Cell Immunol 224: 98-105 PubMed GONUTS page
↑ ^11.0 ^11.1 García-Martínez LF et al. (2004) A novel mutation in CD83 results in the development of a unique population of CD4+ T cells. J Immunol 173: 2995-3001 PubMed GONUTS page
↑ ^12.0 ^12.1 Ye Q et al. (2004) BAFF binding to T cell-expressed BAFF-R costimulates T cell proliferation and alloresponses. Eur J Immunol 34: 2750-9 PubMed GONUTS page
↑ ^13.0 ^13.1 Mandal M et al. (2005) The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival. J Exp Med 201: 603-14 PubMed GONUTS page
↑ ^14.0 ^14.1 Winkler IG et al. (2005) Serine protease inhibitors serpina1 and serpina3 are down-regulated in bone marrow during hematopoietic progenitor mobilization. J Exp Med 201: 1077-88 PubMed GONUTS page
↑ ^15.0 ^15.1 Bultman SJ et al. (2005) A Brg1 mutation that uncouples ATPase activity from chromatin remodeling reveals an essential role for SWI/SNF-related complexes in beta-globin expression and erythroid development. Genes Dev 19: 2849-61 PubMed GONUTS page
↑ ^16.0 ^16.1 Marie JC et al. (2006) Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor. Immunity 25: 441-54 PubMed GONUTS page
↑ ^17.0 ^17.1 Kisielow J et al. (2008) SCART scavenger receptors identify a novel subset of adult gammadelta T cells. J Immunol 181: 1710-6 PubMed GONUTS page
↑ ^18.0 ^18.1 Shiow LR et al. (2008) The actin regulator coronin 1A is mutant in a thymic egress-deficient mouse strain and in a patient with severe combined immunodeficiency. Nat Immunol 9: 1307-15 PubMed GONUTS page
↑ ^19.0 ^19.1 Abe J et al. (2008) Increased Foxp3(+) CD4(+) regulatory T cells with intact suppressive activity but altered cellular localization in murine lupus. Am J Pathol 173: 1682-92 PubMed GONUTS page
↑ ^20.0 ^20.1 Stone EL et al. (2009) Glycosyltransferase function in core 2-type protein O glycosylation. Mol Cell Biol 29: 3770-82 PubMed GONUTS page
↑ ^21.0 ^21.1 Terauchi M et al. (2009) T lymphocytes amplify the anabolic activity of parathyroid hormone through Wnt10b signaling. Cell Metab 10: 229-40 PubMed GONUTS page
↑ ^22.0 ^22.1 Turner M et al. (1995) Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk. Nature 378: 298-302 PubMed GONUTS page
↑ ^23.0 ^23.1 Cheng AM et al. (1995) Syk tyrosine kinase required for mouse viability and B-cell development. Nature 378: 303-6 PubMed GONUTS page
↑ ^24.0 ^24.1 Simpson SJ et al. (1995) Evidence that CD4+, but not CD8+ T cells are responsible for murine interleukin-2-deficient colitis. Eur J Immunol 25: 2618-25 PubMed GONUTS page
↑ ^25.0 ^25.1 Negishi I et al. (1995) Essential role for ZAP-70 in both positive and negative selection of thymocytes. Nature 376: 435-8 PubMed GONUTS page
↑ ^26.0 ^26.1 Shahinian A et al. (1993) Differential T cell costimulatory requirements in CD28-deficient mice. Science 261: 609-12 PubMed GONUTS page
↑ ^27.0 ^27.1 Chu K et al. (1995) A Fas-associated protein factor, FAF1, potentiates Fas-mediated apoptosis. Proc Natl Acad Sci U S A 92: 11894-8 PubMed GONUTS page
↑ ^28.0 ^28.1 Bouvier G et al. (1996) Deletion of the mouse T-cell receptor beta gene enhancer blocks alphabeta T-cell development. Proc Natl Acad Sci U S A 93: 7877-81 PubMed GONUTS page
↑ ^29.0 ^29.1 Hazenbos WL et al. (1996) Impaired IgG-dependent anaphylaxis and Arthus reaction in Fc gamma RIII (CD16) deficient mice. Immunity 5: 181-8 PubMed GONUTS page
↑ ^30.0 ^30.1 Li T et al. (1996) Distinct patterns of Fas cell surface expression during development of T- or B-lymphocyte lineages in normal, scid, and mutant mice lacking or overexpressing p53, bcl-2, or rag-2 genes. Cell Growth Differ 7: 107-14 PubMed GONUTS page
↑ ^31.0 ^31.1 Mendiratta SK et al. (1997) CD1d1 mutant mice are deficient in natural T cells that promptly produce IL-4. Immunity 6: 469-77 PubMed GONUTS page
↑ ^32.0 ^32.1 Sant'Angelo DB et al. (1996) The specificity and orientation of a TCR to its peptide-MHC class II ligands. Immunity 4: 367-76 PubMed GONUTS page
↑ ^33.0 ^33.1 Seong RH et al. (1992) Signal for T-cell differentiation to a CD4 cell lineage is delivered by CD4 transmembrane region and/or cytoplasmic tail. Nature 356: 718-20 PubMed GONUTS page
↑ ^34.0 ^34.1 Frank GD & Parnes JR (1998) The level of CD4 surface protein influences T cell selection in the thymus. J Immunol 160: 634-42 PubMed GONUTS page
↑ ^35.0 ^35.1 ^35.2 ^35.3 Balamuth F et al. (2004) CD4 raft association and signaling regulate molecular clustering at the immunological synapse site. J Immunol 172: 5887-92 PubMed GONUTS page

[PMID:7930593-0] 1.0 ^1.1 ^1.2 ^1.3 Blair PJ et al. (1994) CD4+CD8- T cells are the effector cells in disease pathogenesis in the scurfy (sf) mouse. J Immunol 153: 3764-74 PubMed GONUTS page

[PMID:7664803-1] 2.0 ^2.1 Campbell KS et al. (1995) Interactions between the amino-terminal domain of p56lck and cytoplasmic domains of CD4 and CD8 alpha in yeast. Eur J Immunol 25: 2408-12 PubMed GONUTS page

[PMID:16223484-2] 3.0 ^3.1 ^3.2 ^3.3 Lidén M et al. (2005) The C-terminal region of cis-retinol/androgen dehydrogenase 1 (CRAD1) confers ER localization and in vivo enzymatic function. Exp Cell Res 311: 205-17 PubMed GONUTS page

[PMID:14517216-3] 4.0 ^4.1 Suzuki M et al. (2003) Microtubule-associated [corrected] protein 7 increases the membrane expression of transient receptor potential vanilloid 4 (TRPV4). J Biol Chem 278: 51448-53 PubMed GONUTS page

[PMID:9208839-4] 5.0 ^5.1 ^5.2 ^5.3 ^5.4 ^5.5 ^5.6 ^5.7 Wiest DL et al. (1997) A spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte development. Immunity 6: 663-71 PubMed GONUTS page

[PMID:10072077-5] 6.0 ^6.1 Moriggl R et al. (1999) Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells. Immunity 10: 249-59 PubMed GONUTS page

[PMID:10704459-6] 7.0 ^7.1 Kennedy MK et al. (2000) Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice. J Exp Med 191: 771-80 PubMed GONUTS page

[PMID:10943842-7] 8.0 ^8.1 Tamura K et al. (2000) Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis. Cell 102: 221-31 PubMed GONUTS page

[PMID:12421911-8] 9.0 ^9.1 ^9.2 ^9.3 Workman CJ et al. (2002) Cutting edge: molecular analysis of the negative regulatory function of lymphocyte activation gene-3. J Immunol 169: 5392-5 PubMed GONUTS page

[PMID:14609575-9] 10.0 ^10.1 Matsuzaki J et al. (2003) Successful elimination of memory-type CD8+ T cell subsets by the administration of anti-Gr-1 monoclonal antibody in vivo. Cell Immunol 224: 98-105 PubMed GONUTS page

[PMID:15322158-10] 11.0 ^11.1 García-Martínez LF et al. (2004) A novel mutation in CD83 results in the development of a unique population of CD4+ T cells. J Immunol 173: 2995-3001 PubMed GONUTS page

[PMID:15368291-11] 12.0 ^12.1 Ye Q et al. (2004) BAFF binding to T cell-expressed BAFF-R costimulates T cell proliferation and alloresponses. Eur J Immunol 34: 2750-9 PubMed GONUTS page

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