MOUSE:ADRM1

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Species (Taxon ID)	Mus musculus (Mouse). (taxon:10090)
Gene Name(s)	Adrm1 ( synonyms: Gp110 )
Protein Name(s)	Proteasomal ubiquitin receptor ADRM1 110 kDa cell membrane glycoprotein Gp110 Adhesion-regulating molecule 1 ARM-1 Rpn13 homolog
External Links
UniProt Identifier	ADRM1_MOUSE
UniProt Accessions	Q9JKV1, Q3UKZ8, Q8BPH8, Q922A7,
EMBL	AF225959, AK075674, AK145474, AK145792, AK166878, AL663027, BC008974, BC031517,
RefSeq	NP_062796.2,
PDB	2R2Y, 2Z59,
Ensembl	ENSMUST00000061437,
Pfam	PF04683,

Annotations

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes	Status
	GO:0005737	cytoplasm		IEA: Inferred from Electronic Annotation		C	Source: UniProtKB-SubCell
	GO:0005634	nucleus		IEA: Inferred from Electronic Annotation		C	Source: UniProtKB-SubCell
	GO:0000502	proteasome complex		IEA: Inferred from Electronic Annotation		C	Source: UniProtKB-KW
	GO:0007283	spermatogenesis	21048919	IMP: Inferred from Mutant Phenotype		P	Histological analysis of 12 weeks old Rpn13 -/- male mice revealed azoospermia (Figure 6).	complete
	GO:0035239	tube morphogenesis	21048919	IMP: Inferred from Mutant Phenotype		P	Histological analysis of 12 weeks old Rpn13-/- male mice revealed hypoplasia of seminiferous tubules(Figure 6).	complete
	GO:0061039	ovum-producing ovary development	21048919	IMP: Inferred from Mutant Phenotype		P	In contrast, in young female Rpn13-/- mice there were relatively few ova and those present were surrounded by a single layer of cells.	complete
	GO:0070341	fat cell proliferation	21048919	IMP: Inferred from Mutant Phenotype		P	Independent of body weight, gender, or age, all Rpn13-/- mice had significantly higher body fat content detected by NMR analysis(Figure 5B)	complete
	GO:0000502	proteasome complex	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0647	C
	GO:0001541	ovarian follicle development	PMID:21048919^[1]	IMP: Inferred from Mutant Phenotype		P
	GO:0005634	nucleus	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR006773	C
	GO:0005634	nucleus	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0539	C
	GO:0005634	nucleus	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0191	C
	GO:0005737	cytoplasm	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR006773	C
	GO:0005737	cytoplasm	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0963	C
	GO:0005737	cytoplasm	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0086	C
	GO:0007286	spermatid development	PMID:21048919^[1]	IMP: Inferred from Mutant Phenotype		P
	GO:0033081	regulation of T cell differentiation in thymus	PMID:21048919^[1]	IMP: Inferred from Mutant Phenotype		P
	GO:0042699	follicle-stimulating hormone signaling pathway	PMID:21048919^[1]	IMP: Inferred from Mutant Phenotype		P
	GO:0048477	oogenesis	PMID:21048919^[1]	IMP: Inferred from Mutant Phenotype		P
	GO:0048538	thymus development	PMID:21048919^[1]	IMP: Inferred from Mutant Phenotype		P
	GO:0060009	Sertoli cell development	PMID:21048919^[1]	IMP: Inferred from Mutant Phenotype		P
	GO:0060399	positive regulation of growth hormone receptor signaling pathway	PMID:21048919^[1]	IMP: Inferred from Mutant Phenotype		P
	GO:0060612	adipose tissue development	PMID:21048919^[1]	IMP: Inferred from Mutant Phenotype		P
	GO:0072520	seminiferous tubule development	PMID:21048919^[1]	IMP: Inferred from Mutant Phenotype		P
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 ^1.8 ^1.9 Al-Shami A et al. (2010) Regulators of the proteasome pathway, Uch37 and Rpn13, play distinct roles in mouse development. PLoS One 5: e13654 PubMed GONUTS page

[PMID:21048919-0] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 ^1.8 ^1.9 Al-Shami A et al. (2010) Regulators of the proteasome pathway, Uch37 and Rpn13, play distinct roles in mouse development. PLoS One 5: e13654 PubMed GONUTS page

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MOUSE:ADRM1

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