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MGI:a
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | a ( synonyms: agouti, agouti signal protein, As, ASP ) | |
| Protein Name(s) | nonagouti, | |
| External Links | ||
| MGI | MGI:87853 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005515 |
protein binding |
MGI:MGI:1929043 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005576 |
extracellular region |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0964 |
C |
From MGI |
||
| GO:0005576 |
extracellular region |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0005623 |
cell |
MGI:MGI:1202196 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1855937 |
C |
From MGI |
||
| GO:0006091 |
generation of precursor metabolites and energy |
MGI:MGI:3721169 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1343180 |
P |
From MGI |
||
| GO:0008343 |
adult feeding behavior |
MGI:MGI:3757819 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:2153518 |
P |
From MGI |
||
| GO:0008343 |
adult feeding behavior |
MGI:MGI:3757819 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1855937 |
P |
From MGI |
||
| GO:0009755 |
hormone-mediated signaling pathway |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0031779 |
melanocortin receptor binding |
MGI:MGI:1195529 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0031781 |
type 3 melanocortin receptor binding |
MGI:MGI:1195529 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0031782 |
type 4 melanocortin receptor binding |
MGI:MGI:1195529 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0032402 |
melanosome transport |
MGI:MGI:1202196 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1855937 |
P |
From MGI |
||
| GO:0032438 |
melanosome organization |
MGI:MGI:1202196 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1855937 |
P |
From MGI |
||
| GO:0040030 |
regulation of molecular function, epigenetic |
MGI:MGI:2652932 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1855937 |
P |
From MGI |
||
| GO:0042438 |
melanin biosynthetic process |
MGI:MGI:76308 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1855937 |
P |
From MGI |
||
| GO:0043473 |
pigmentation |
MGI:MGI:61184 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856798 |
P |
From MGI |
||
| GO:0071514 |
genetic imprinting |
MGI:MGI:2652932 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1855937 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ He L et al. (2001) A biochemical function for attractin in agouti-induced pigmentation and obesity. Nat Genet 27: 40-7 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Hirobe T et al. (1998) Effects of genic substitution at the agouti, brown, albino, dilute, and pink-eyed dilution loci on the proliferation and differentiation of mouse epidermal melanocytes in serum-free culture. Eur J Cell Biol 75: 184-91 PubMed GONUTS page
- ↑ Hahm S et al. (2002) VGF is required for obesity induced by diet, gold thioglucose treatment, and agouti and is differentially regulated in pro-opiomelanocortin- and neuropeptide Y-containing arcuate neurons in response to fasting. J Neurosci 22: 6929-38 PubMed GONUTS page
- ↑ 4.0 4.1 Fujimoto W et al. (2007) Dmbx1 is essential in agouti-related protein action. Proc Natl Acad Sci U S A 104: 15514-9 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Kiefer LL et al. (1998) Melanocortin receptor binding determinants in the agouti protein. Biochemistry 37: 991-7 PubMed GONUTS page
- ↑ 6.0 6.1 Rakyan VK et al. (2003) Transgenerational inheritance of epigenetic states at the murine Axin(Fu) allele occurs after maternal and paternal transmission. Proc Natl Acad Sci U S A 100: 2538-43 PubMed GONUTS page
- ↑ Ozeki H et al. (1995) Chemical characterization of hair melanins in various coat-color mutants of mice. J Invest Dermatol 105: 361-6 PubMed GONUTS page
- ↑ Markert CL & Silvers WK (1956) The Effects of Genotype and Cell Environment on Melanoblast Differentiation in the House Mouse. Genetics 41: 429-50 PubMed GONUTS page
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