GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
MGI:Zeb2
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Zeb2 ( synonyms: SIP1, Zfhx1b, Zfx1b ) | |
| Protein Name(s) | zinc finger E-box binding homeobox 2, | |
| External Links | ||
| MGI | MGI:1344407 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001755 |
neural crest cell migration |
MGI:MGI:2450818 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2387501 |
P |
From MGI |
||
| GO:0001756 |
somitogenesis |
MGI:MGI:3590396 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2387501 |
P |
From MGI |
||
| GO:0001756 |
somitogenesis |
MGI:MGI:3624924 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2387501 |
P |
From MGI |
||
| GO:0001843 |
neural tube closure |
MGI:MGI:3624924 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2387501 |
P |
From MGI |
||
| GO:0003676 |
nucleic acid binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0003677 |
DNA binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0238 |
F |
From MGI |
||
| GO:0003677 |
DNA binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005730 |
nucleolus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0805 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007417 |
central nervous system development |
MGI:MGI:3624924 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1344313 |
P |
From MGI |
||
| GO:0008270 |
zinc ion binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0021766 |
hippocampus development |
MGI:MGI:3718270 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2387499 |
P |
From MGI |
||
| GO:0021846 |
cell proliferation in forebrain |
MGI:MGI:3718270 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2387499 |
P |
From MGI |
||
| GO:0030177 |
positive regulation of Wnt receptor signaling pathway |
MGI:MGI:3718270 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2387499 |
P |
From MGI |
||
| GO:0043507 |
positive regulation of JUN kinase activity |
MGI:MGI:3718270 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2387499 |
P |
From MGI |
||
| GO:0043565 |
sequence-specific DNA binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0046872 |
metal ion binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From MGI |
||
| GO:0048598 |
embryonic morphogenesis |
MGI:MGI:3624924 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1344313 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Van de Putte T et al. (2003) Mice lacking ZFHX1B, the gene that codes for Smad-interacting protein-1, reveal a role for multiple neural crest cell defects in the etiology of Hirschsprung disease-mental retardation syndrome. Am J Hum Genet 72: 465-70 PubMed GONUTS page
- ↑ Molyneaux BJ et al. (2005) Fezl is required for the birth and specification of corticospinal motor neurons. Neuron 47: 817-31 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Miyoshi T et al. (2006) Complementary expression pattern of Zfhx1 genes Sip1 and deltaEF1 in the mouse embryo and their genetic interaction revealed by compound mutants. Dev Dyn 235: 1941-52 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Miquelajauregui A et al. (2007) Smad-interacting protein-1 (Zfhx1b) acts upstream of Wnt signaling in the mouse hippocampus and controls its formation. Proc Natl Acad Sci U S A 104: 12919-24 PubMed GONUTS page
