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MGI:Yy1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Yy1 ( synonyms: delta transcription factor, NF-E1, UCRBP transcription factor, Yin Yang 1 )
Protein Name(s) YY1 transcription factor,
External Links
MGI MGI:99150

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:1321421
PMID:9857059[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:1321421
PMID:9857059[1]

ISO: Inferred from Sequence Orthology

UniProtKB:P25490

P

From MGI

GO:0000400

four-way junction DNA binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P25490

F

From MGI

GO:0000724

double-strand break repair via homologous recombination

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P25490

P

From MGI

GO:0003676

nucleic acid binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR013087

F

From MGI

GO:0003677

DNA binding

MGI:MGI:2449867
PMID:12527199[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003677

DNA binding

MGI:MGI:3052290
PMID:15161869[3]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003677

DNA binding

MGI:MGI:3511714
PMID:15574595[4]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003677

DNA binding

MGI:MGI:5051946
PMID:21729784[5]

ISO: Inferred from Sequence Orthology

UniProtKB:P25490

F

From MGI

GO:0003700

sequence-specific DNA binding transcription factor activity

MGI:MGI:2159570
PMID:11861914[6]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003723

RNA binding

MGI:MGI:5051946
PMID:21729784[5]

ISO: Inferred from Sequence Orthology

UniProtKB:P25490

F

From MGI

GO:0005622

intracellular

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR007087
InterPro:IPR015880

C

From MGI

GO:0005634

nucleus

MGI:MGI:1321421
PMID:9857059[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005634

nucleus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_775412

C

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P25490

C

From MGI

GO:0005667

transcription factor complex

MGI:MGI:2159570
PMID:11861914[6]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005667

transcription factor complex

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_775412

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P25490

C

From MGI

GO:0006281

DNA repair

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0234

P

From MGI

GO:0006310

DNA recombination

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0233

P

From MGI

GO:0006351

transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:2159570
PMID:11861914[6]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_775412

P

From MGI

GO:0006403

RNA localization

MGI:MGI:5051946
PMID:21729784[5]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0006974

response to DNA damage stimulus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P25490

P

From MGI

GO:0006974

response to DNA damage stimulus

MGI:MGI:5009388
PMID:18026119[7]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0007283

spermatogenesis

MGI:MGI:4412132
PMID:19786570[8]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0008270

zinc ion binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR007087
InterPro:IPR015880

F

From MGI

GO:0009952

anterior/posterior pattern specification

MGI:MGI:3628673
PMID:16624538[9]

IGI: Inferred from Genetic Interaction

MGI:MGI:1101770

P

From MGI

GO:0009952

anterior/posterior pattern specification

MGI:MGI:3628673
PMID:16624538[9]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2445451

P

From MGI

GO:0010225

response to UV-C

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P25490

P

From MGI

GO:0010225

response to UV-C

MGI:MGI:5009388
PMID:18026119[7]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0030154

cell differentiation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0221

P

From MGI

GO:0031011

Ino80 complex

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P25490

C

From MGI

GO:0031519

PcG protein complex

MGI:MGI:3628673
PMID:16624538[9]

IDA: Inferred from Direct Assay

C

From MGI

GO:0034644

cellular response to UV

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P25490

P

From MGI

GO:0044212

transcription regulatory region DNA binding

MGI:MGI:1321421
PMID:9857059[1]

ISO: Inferred from Sequence Orthology

UniProtKB:P25490

F

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI

GO:0048593

camera-type eye morphogenesis

MGI:MGI:3628673
PMID:16624538[9]

IGI: Inferred from Genetic Interaction

MGI:MGI:1101770

P

From MGI

GO:0051276

chromosome organization

MGI:MGI:5009388
PMID:18026119[7]

IMP: Inferred from Mutant Phenotype

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Du K et al. (1998) Transcriptional up-regulation of the delayed early gene HRS/SRp40 during liver regeneration. Interactions among YY1, GA-binding proteins, and mitogenic signals. J Biol Chem 273: 35208-15 PubMed GONUTS page
  2. Shou Z et al. (2003) Genomic structure and analysis of transcriptional regulation of the mouse zinc-fingers and homeoboxes 1 (ZHX1) gene. Gene 302: 83-94 PubMed GONUTS page
  3. Bravo-Nuevo A et al. (2004) Photoreceptor degeneration and loss of retinal function in the C57BL/6-C2J mouse. Invest Ophthalmol Vis Sci 45: 2005-12 PubMed GONUTS page
  4. Giangrande PH et al. (2004) A role for E2F6 in distinguishing G1/S- and G2/M-specific transcription. Genes Dev 18: 2941-51 PubMed GONUTS page
  5. 5.0 5.1 5.2 Jeon Y & Lee JT (2011) YY1 tethers Xist RNA to the inactive X nucleation center. Cell 146: 119-33 PubMed GONUTS page
  6. 6.0 6.1 6.2 Tan DP et al. (2002) YY1 activates Msx2 gene independent of bone morphogenetic protein signaling. Nucleic Acids Res 30: 1213-23 PubMed GONUTS page
  7. 7.0 7.1 7.2 Wu S et al. (2007) A YY1-INO80 complex regulates genomic stability through homologous recombination-based repair. Nat Struct Mol Biol 14: 1165-72 PubMed GONUTS page
  8. Wu S et al. (2009) Loss of YY1 impacts the heterochromatic state and meiotic double-strand breaks during mouse spermatogenesis. Mol Cell Biol 29: 6245-56 PubMed GONUTS page
  9. 9.0 9.1 9.2 9.3 Lorente M et al. (2006) Homeotic transformations of the axial skeleton of YY1 mutant mice and genetic interaction with the Polycomb group gene Ring1/Ring1A. Mech Dev 123: 312-20 PubMed GONUTS page
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