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MGI:Ybx2
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Ybx2 ( synonyms: MSY2 ) | |
| Protein Name(s) | Y box protein 2, | |
| External Links | ||
| MGI | MGI:1096372 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003676 |
nucleic acid binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0003677 |
DNA binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0238 |
F |
From MGI |
||
| GO:0003677 |
DNA binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0003682 |
chromatin binding |
MGI:MGI:3529406 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003723 |
RNA binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0694 |
F |
From MGI |
||
| GO:0003729 |
mRNA binding |
MGI:MGI:2387497 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003729 |
mRNA binding |
MGI:MGI:2654284 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003729 |
mRNA binding |
MGI:MGI:3529406 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003729 |
mRNA binding |
MGI:MGI:3696301 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003730 |
mRNA 3'-UTR binding |
MGI:MGI:1930944 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0539 |
C |
From MGI |
||
| GO:0005737 |
cytoplasm |
MGI:MGI:2151306 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:2654284 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:XP_001079683 |
C |
From MGI |
||
| GO:0005844 |
polysome |
MGI:MGI:3696301 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007286 |
spermatid development |
MGI:MGI:3576442 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3576937 |
P |
From MGI |
||
| GO:0007286 |
spermatid development |
MGI:MGI:3696301 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3576937 |
P |
From MGI |
||
| GO:0008289 |
lipid binding |
MGI:MGI:3529406 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0017148 |
negative regulation of translation |
MGI:MGI:3529406 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0030529 |
ribonucleoprotein complex |
MGI:MGI:3529406 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0043021 |
ribonucleoprotein complex binding |
MGI:MGI:3696301 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0045182 |
translation regulator activity |
MGI:MGI:2387497 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0048255 |
mRNA stabilization |
MGI:MGI:3696301 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3576937 |
P |
From MGI |
||
| GO:0048477 |
oogenesis |
MGI:MGI:3576442 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3576937 |
P |
From MGI |
||
| GO:0051100 |
negative regulation of binding |
MGI:MGI:3696301 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3576937 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Yang J et al. (2005) The DNA/RNA-binding protein MSY2 marks specific transcripts for cytoplasmic storage in mouse male germ cells. Proc Natl Acad Sci U S A 102: 1513-8 PubMed GONUTS page
- ↑ 2.0 2.1 Yu J et al. (2002) RNA-binding properties and translation repression in vitro by germ cell-specific MSY2 protein. Biol Reprod 67: 1093-8 PubMed GONUTS page
- ↑ 3.0 3.1 Yu J et al. (2003) Requirement for RNA-binding activity of MSY2 for cytoplasmic localization and retention in mouse oocytes. Dev Biol 255: 249-62 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 Yang J et al. (2007) In the absence of the mouse DNA/RNA-binding protein MSY2, messenger RNA instability leads to spermatogenic arrest. Biol Reprod 76: 48-54 PubMed GONUTS page
- ↑ Davies HG et al. (2000) A sequence-specific RNA binding complex expressed in murine germ cells contains MSY2 and MSY4. Dev Biol 221: 87-100 PubMed GONUTS page
- ↑ Yu J et al. (2001) Expression of MSY2 in mouse oocytes and preimplantation embryos. Biol Reprod 65: 1260-70 PubMed GONUTS page
- ↑ 7.0 7.1 Yang J et al. (2005) Absence of the DNA-/RNA-binding protein MSY2 results in male and female infertility. Proc Natl Acad Sci U S A 102: 5755-60 PubMed GONUTS page
