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MGI:Xrcc6
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Xrcc6 ( synonyms: G22p1, Ku p70, Ku70 ) | |
| Protein Name(s) | X-ray repair complementing defective repair in Chinese hamster cells 6, | |
| External Links | ||
| MGI | MGI:95606 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0547 |
F |
From MGI |
||
| GO:0003676 |
nucleic acid binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0003677 |
DNA binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0238 |
F |
From MGI |
||
| GO:0003677 |
DNA binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0003824 |
catalytic activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0511 |
F |
From MGI |
||
| GO:0004003 |
ATP-dependent DNA helicase activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0004386 |
helicase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0347 |
F |
From MGI |
||
| GO:0005524 |
ATP binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0067 |
F |
From MGI |
||
| GO:0005634 |
nucleus |
MGI:MGI:2450507 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_620780 |
C |
From MGI |
||
| GO:0005667 |
transcription factor complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005694 |
chromosome |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0158 |
C |
From MGI |
||
| GO:0005730 |
nucleolus |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_620780 |
C |
From MGI |
||
| GO:0005737 |
cytoplasm |
MGI:MGI:2450507 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_620780 |
C |
From MGI |
||
| GO:0005958 |
DNA-dependent protein kinase-DNA ligase 4 complex |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0006200 |
ATP catabolic process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0006281 |
DNA repair |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0234 |
P |
From MGI |
||
| GO:0006302 |
double-strand break repair |
MGI:MGI:2155497 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2179954 |
P |
From MGI |
||
| GO:0006303 |
double-strand break repair via nonhomologous end joining |
MGI:MGI:2155497 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2179954 |
P |
From MGI |
||
| GO:0006303 |
double-strand break repair via nonhomologous end joining |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006310 |
DNA recombination |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0233 |
P |
From MGI |
||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0805 |
P |
From MGI |
||
| GO:0006974 |
response to DNA damage stimulus |
MGI:MGI:3613277 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2179954 |
P |
From MGI |
||
| GO:0008022 |
protein C-terminus binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0008152 |
metabolic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0511 |
P |
From MGI |
||
| GO:0010212 |
response to ionizing radiation |
MGI:MGI:3613277 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2179954 |
P |
From MGI |
||
| GO:0016787 |
hydrolase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0378 |
F |
From MGI |
||
| GO:0016829 |
lyase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0456 |
F |
From MGI |
||
| GO:0032508 |
DNA duplex unwinding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0033151 |
V(D)J recombination |
MGI:MGI:3641390 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2179954 |
P |
From MGI |
||
| GO:0043234 |
protein complex |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_620780 |
C |
From MGI |
||
| GO:0043564 |
Ku70:Ku80 complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0044212 |
transcription regulatory region DNA binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045893 |
positive regulation of transcription, DNA-dependent |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0050769 |
positive regulation of neurogenesis |
MGI:MGI:3641390 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2179954 |
P |
From MGI |
||
| GO:0051575 |
5'-deoxyribose-5-phosphate lyase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0070419 |
nonhomologous end joining complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0071475 |
cellular hyperosmotic salinity response |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_620780 |
P |
From MGI |
||
| GO:0071481 |
cellular response to X-ray |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_620780 |
P |
From MGI |
||
|
contributes_to |
GO:0003690 |
double-stranded DNA binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_620780 |
F |
From MGI |
|
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Hamer G et al. (2003) Function of DNA-protein kinase catalytic subunit during the early meiotic prophase without Ku70 and Ku86. Biol Reprod 68: 717-21 PubMed GONUTS page
- ↑ 2.0 2.1 Pierce AJ et al. (2001) Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells. Genes Dev 15: 3237-42 PubMed GONUTS page
- ↑ 3.0 3.1 Griffin C et al. (2005) The involvement of key DNA repair pathways in the formation of chromosome rearrangements in embryonic stem cells. DNA Repair (Amst) 4: 1019-27 PubMed GONUTS page
- ↑ 4.0 4.1 Gu Y et al. (2000) Defective embryonic neurogenesis in Ku-deficient but not DNA-dependent protein kinase catalytic subunit-deficient mice. Proc Natl Acad Sci U S A 97: 2668-73 PubMed GONUTS page
