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MGI:Xpc

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Xpc
Protein Name(s) xeroderma pigmentosum, complementation group C,
External Links
MGI MGI:103557

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000075

cell cycle checkpoint

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q01831

P

From MGI

GO:0000715

nucleotide-excision repair, DNA damage recognition

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q01831

P

From MGI

GO:0003677

DNA binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238

F

From MGI

GO:0003677

DNA binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR018326
InterPro:IPR018327
InterPro:IPR018328

F

From MGI

GO:0003684

damaged DNA binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q01831

F

From MGI

GO:0003697

single-stranded DNA binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q01831

F

From MGI

GO:0005634

nucleus

MGI:MGI:2667287
PMID:12815074[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005634

nucleus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001101344

C

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q01831

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001101344

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q01831

C

From MGI

GO:0006281

DNA repair

MGI:MGI:2445277
PMID:12555660[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1859840

P

From MGI

GO:0006289

nucleotide-excision repair

MGI:MGI:2667287
PMID:12815074[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006289

nucleotide-excision repair

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q01831

P

From MGI

GO:0006289

nucleotide-excision repair

MGI:MGI:86029
PMID:9067411[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1859840

P

From MGI

GO:0006974

response to DNA damage stimulus

MGI:MGI:3034118
PMID:15010313[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1859840

P

From MGI

GO:0010224

response to UV-B

MGI:MGI:3034118
PMID:15010313[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1859840

P

From MGI

GO:0031573

intra-S DNA damage checkpoint

MGI:MGI:3512823
PMID:15533840[5]

IGI: Inferred from Genetic Interaction

MGI:MGI:101816

P

From MGI

GO:0071942

XPC complex

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q01831

C

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Ng JM et al. (2003) A novel regulation mechanism of DNA repair by damage-induced and RAD23-dependent stabilization of xeroderma pigmentosum group C protein. Genes Dev 17: 1630-45 PubMed GONUTS page
  2. Schenten D et al. (2002) DNA polymerase kappa deficiency does not affect somatic hypermutation in mice. Eur J Immunol 32: 3152-60 PubMed GONUTS page
  3. Cheo DL et al. (1997) Characterization of defective nucleotide excision repair in XPC mutant mice. Mutat Res 374: 1-9 PubMed GONUTS page
  4. 4.0 4.1 Nahari D et al. (2004) Mutations in the Trp53 gene of UV-irradiated Xpc mutant mice suggest a novel Xpc-dependent DNA repair process. DNA Repair (Amst) 3: 379-86 PubMed GONUTS page
  5. van Oosten M et al. (2005) Mismatch repair protein Msh2 contributes to UVB-induced cell cycle arrest in epidermal and cultured mouse keratinocytes. DNA Repair (Amst) 4: 81-9 PubMed GONUTS page
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