Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

MGI:Xirp1

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Xirp1 ( synonyms: Cmya1, mXin alpha, Xin )
Protein Name(s) xin actin-binding repeat containing 1,
External Links
MGI MGI:1333878

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003007

heart morphogenesis

MGI:MGI:1329802
PMID:10021346[1]

ISA: Inferred from Sequence Alignment

EMBL:AF051944

P

From MGI

GO:0005886

plasma membrane

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q702N8

C

From MGI

GO:0005913

cell-cell adherens junction

MGI:MGI:2386380
PMID:12203715[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005916

fascia adherens

MGI:MGI:1329802
PMID:10021346[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005916

fascia adherens

MGI:MGI:3655786
PMID:16708114[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0008285

negative regulation of cell proliferation

MGI:MGI:3767901
PMID:17855775[4]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0014704

intercalated disc

MGI:MGI:3775114
PMID:17766470[5]

IDA: Inferred from Direct Assay

C

From MGI

GO:0031005

filamin binding

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

RefSeq:NM_194293

F

From MGI

GO:0042391

regulation of membrane potential

MGI:MGI:3775114
PMID:17766470[5]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3521795

P

From MGI

GO:0045214

sarcomere organization

MGI:MGI:3775114
PMID:17766470[5]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3521795

P

From MGI

GO:0055013

cardiac muscle cell development

MGI:MGI:3775114
PMID:17766470[5]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3521795

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Wang DZ et al. (1999) Requirement of a novel gene, Xin, in cardiac morphogenesis. Development 126: 1281-94 PubMed GONUTS page
  2. Sinn HW et al. (2002) Localization of the novel Xin protein to the adherens junction complex in cardiac and skeletal muscle during development. Dev Dyn 225: 1-13 PubMed GONUTS page
  3. Jung-Ching Lin J et al. (2005) Structure, Expression, and Function of a Novel Intercalated Disc Protein, Xin. J Med Sci 25: 215-222 PubMed GONUTS page
  4. Hawke TJ et al. (2007) Xin, an actin binding protein, is expressed within muscle satellite cells and newly regenerated skeletal muscle fibers. Am J Physiol Cell Physiol 293: C1636-44 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 Gustafson-Wagner EA et al. (2007) Loss of mXinalpha, an intercalated disk protein, results in cardiac hypertrophy and cardiomyopathy with conduction defects. Am J Physiol Heart Circ Physiol 293: H2680-92 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox