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MGI:Xdh

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Xdh ( synonyms: xanthine oxidase, XO, Xor, Xox-1, Xox1 )
Protein Name(s) xanthine dehydrogenase,
External Links
MGI MGI:98973

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003824

catalytic activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR016166
InterPro:IPR016167

F

From MGI

GO:0004854

xanthine dehydrogenase activity

MGI:MGI:2447927
PMID:12502743[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004854

xanthine dehydrogenase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q62637

F

From MGI

GO:0004855

xanthine oxidase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q62637

F

From MGI

GO:0004855

xanthine oxidase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P47989

F

From MGI

GO:0005506

iron ion binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR016208

F

From MGI

GO:0005515

protein binding

MGI:MGI:77769
PMID:8541302[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q62556

F

From MGI

GO:0005576

extracellular region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

From MGI

GO:0005777

peroxisome

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0576

C

From MGI

GO:0005829

cytosol

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q62637

C

From MGI

GO:0007595

lactation

MGI:MGI:2447927
PMID:12502743[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2448161

P

From MGI

GO:0008152

metabolic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR016166
InterPro:IPR016167

P

From MGI

GO:0008762

UDP-N-acetylmuramate dehydrogenase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR016167

F

From MGI

GO:0009055

electron carrier activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001041

F

From MGI

GO:0009115

xanthine catabolic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q62637

P

From MGI

GO:0009115

xanthine catabolic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P47989

P

From MGI

GO:0010044

response to aluminum ion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q62637

P

From MGI

GO:0016491

oxidoreductase activity

MGI:MGI:3770334
PMID:17597094[3]

IDA: Inferred from Direct Assay

F

From MGI

GO:0016614

oxidoreductase activity, acting on CH-OH group of donors

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR016166

F

From MGI

GO:0030151

molybdenum ion binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR014309

F

From MGI

GO:0030856

regulation of epithelial cell differentiation

MGI:MGI:2447927
PMID:12502743[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2448161

P

From MGI

GO:0042803

protein homodimerization activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P47989

F

From MGI

GO:0043546

molybdopterin cofactor binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q62637

F

From MGI

GO:0043546

molybdopterin cofactor binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P47989

F

From MGI

GO:0045453

bone resorption

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q62637

P

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI

GO:0046872

metal ion binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR002888

F

From MGI

GO:0050660

flavin adenine dinucleotide binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q62637

F

From MGI

GO:0050660

flavin adenine dinucleotide binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P47989

F

From MGI

GO:0051536

iron-sulfur cluster binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0411

F

From MGI

GO:0051536

iron-sulfur cluster binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001041

F

From MGI

GO:0051537

2 iron, 2 sulfur cluster binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q62637

F

From MGI

GO:0051537

2 iron, 2 sulfur cluster binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P47989

F

From MGI

GO:0055114

oxidation-reduction process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR016166

P

From MGI

GO:0055114

oxidation-reduction process

MGI:MGI:3770334
PMID:17597094[3]

IDA: Inferred from Direct Assay

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Vorbach C et al. (2002) The housekeeping gene xanthine oxidoreductase is necessary for milk fat droplet enveloping and secretion: gene sharing in the lactating mammary gland. Genes Dev 16: 3223-35 PubMed GONUTS page
  2. Ishii T et al. (1995) Carboxy-terminal cytoplasmic domain of mouse butyrophilin specifically associates with a 150-kDa protein of mammary epithelial cells and milk fat globule membrane. Biochim Biophys Acta 1245: 285-92 PubMed GONUTS page
  3. 3.0 3.1 Martelli A et al. (2007) Frataxin is essential for extramitochondrial Fe-S cluster proteins in mammalian tissues. Hum Mol Genet 16: 2651-8 PubMed GONUTS page
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