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MGI:Wnt9b

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Wnt9b ( synonyms: clf, clf1, Wnt14b, Wnt15 )
Protein Name(s) wingless-type MMTV integration site 9B,
External Links
MGI MGI:1197020

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:4459044

PANTHER:PTHR12027

P

From MGI

GO:0001658

branching involved in ureteric bud morphogenesis

MGI:MGI:3588895
PMID:16054034[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:98953

P

From MGI

GO:0001658

branching involved in ureteric bud morphogenesis

MGI:MGI:3588895
PMID:16054034[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3526437

P

From MGI

GO:0001664

G-protein coupled receptor binding

MGI:MGI:4459044

PANTHER:PTHR12027

F

From MGI

GO:0001701

in utero embryonic development

MGI:MGI:3588895
PMID:16054034[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3526437

P

From MGI

GO:0001822

kidney development

MGI:MGI:4353952
PMID:19543268[2]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0001932

regulation of protein phosphorylation

MGI:MGI:4353952
PMID:19543268[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3526437

P

From MGI

GO:0003339

regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis

MGI:MGI:3588895
PMID:16054034[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0003339

regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis

MGI:MGI:3588895
PMID:16054034[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3526437

P

From MGI

GO:0005102

receptor binding

MGI:MGI:1327700
PMID:9889131[3]

TAS: Traceable Author Statement

F

From MGI

GO:0005576

extracellular region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From MGI

GO:0005576

extracellular region

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR005817

C

From MGI

GO:0005578

proteinaceous extracellular matrix

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0272

C

From MGI

GO:0005615

extracellular space

MGI:MGI:4459044

PANTHER:PTHR12027

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:4459044

PANTHER:PTHR12027

C

From MGI

GO:0007165

signal transduction

MGI:MGI:1327700
PMID:9889131[3]

TAS: Traceable Author Statement

P

From MGI

GO:0007267

cell-cell signaling

MGI:MGI:1327700
PMID:9889131[3]

TAS: Traceable Author Statement

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR005817

P

From MGI

GO:0007492

endoderm development

MGI:MGI:4459044

PANTHER:PTHR12027

P

From MGI

GO:0009786

regulation of asymmetric cell division

MGI:MGI:4353952
PMID:19543268[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3805020

P

From MGI

GO:0009798

axis specification

MGI:MGI:4459044

PANTHER:PTHR12027

P

From MGI

GO:0009887

organ morphogenesis

MGI:MGI:1327700
PMID:9889131[3]

TAS: Traceable Author Statement

P

From MGI

GO:0009952

anterior/posterior pattern specification

MGI:MGI:4459044

PANTHER:PTHR12027

P

From MGI

GO:0016055

Wnt receptor signaling pathway

MGI:MGI:3588895
PMID:16054034[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3526437

P

From MGI

GO:0030539

male genitalia development

MGI:MGI:3588895
PMID:16054034[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3526437

P

From MGI

GO:0035150

regulation of tube size

MGI:MGI:4353952
PMID:19543268[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3805020
MGI:MGI:3526437

P

From MGI

GO:0043085

positive regulation of catalytic activity

MGI:MGI:4353952
PMID:19543268[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3526437

P

From MGI

GO:0048701

embryonic cranial skeleton morphogenesis

MGI:MGI:3588895
PMID:16054034[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3526437

P

From MGI

GO:0048701

embryonic cranial skeleton morphogenesis

MGI:MGI:3696935
PMID:16998816[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3526437
MGI:MGI:1856821

P

From MGI

GO:0048754

branching morphogenesis of a tube

MGI:MGI:3588895
PMID:16054034[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3526437

P

From MGI

GO:0060021

palate development

MGI:MGI:3588895
PMID:16054034[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3526437

P

From MGI

GO:0060070

canonical Wnt receptor signaling pathway

MGI:MGI:4459044

PANTHER:PTHR12027

P

From MGI

GO:0060071

Wnt receptor signaling pathway, planar cell polarity pathway

MGI:MGI:4353952
PMID:19543268[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3526437

P

From MGI

GO:0060993

kidney morphogenesis

MGI:MGI:3588895
PMID:16054034[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3526437
MGI:MGI:3526436

P

From MGI

GO:0061038

uterus morphogenesis

MGI:MGI:3588895
PMID:16054034[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3526437

P

From MGI

GO:0072003

kidney rudiment formation

MGI:MGI:3588895
PMID:16054034[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3526437

P

From MGI

GO:0072044

collecting duct development

MGI:MGI:3588895
PMID:16054034[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3526437

P

From MGI

GO:0072046

establishment of planar polarity involved in nephron morphogenesis

MGI:MGI:4353952
PMID:19543268[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3805020
MGI:MGI:3526437

P

From MGI

GO:0072078

nephron tubule morphogenesis

MGI:MGI:4353952
PMID:19543268[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3805020
MGI:MGI:3526437

P

From MGI

GO:0072164

mesonephric tubule development

MGI:MGI:3588895
PMID:16054034[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3526437

P

From MGI

GO:0072164

mesonephric tubule development

MGI:MGI:4430439
PMID:20040500[5]

IGI: Inferred from Genetic Interaction

MGI:MGI:98505

P

From MGI

GO:0072170

metanephric tubule development

MGI:MGI:3588895
PMID:16054034[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3526437

P

From MGI

GO:0072181

mesonephric duct formation

MGI:MGI:3588895
PMID:16054034[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3526437

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 1.15 1.16 Carroll TJ et al. (2005) Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system. Dev Cell 9: 283-92 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 Karner CM et al. (2009) Wnt9b signaling regulates planar cell polarity and kidney tubule morphogenesis. Nat Genet 41: 793-9 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Loureiro JJ (1999) The Wnts. Curr Biol 9: R4 PubMed GONUTS page
  4. Juriloff DM et al. (2006) Wnt9b is the mutated gene involved in multifactorial nonsyndromic cleft lip with or without cleft palate in A/WySn mice, as confirmed by a genetic complementation test. Birth Defects Res A Clin Mol Teratol 76: 574-9 PubMed GONUTS page
  5. Lokmane L et al. (2010) vHNF1 functions in distinct regulatory circuits to control ureteric bud branching and early nephrogenesis. Development 137: 347-57 PubMed GONUTS page
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