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MGI:Wnt6

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Wnt6 ( synonyms: Wnt-6 )
Protein Name(s) wingless-related MMTV integration site 6,
External Links
MGI MGI:98960

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:4459044

PANTHER:PTHR12027

P

From MGI

GO:0001658

branching involved in ureteric bud morphogenesis

MGI:MGI:2178881
PMID:11948913[1]

IGI: Inferred from Genetic Interaction

UniProtKB:P22724

P

From MGI

GO:0001664

G-protein coupled receptor binding

MGI:MGI:4459044

PANTHER:PTHR12027

F

From MGI

GO:0005102

receptor binding

MGI:MGI:1327700
PMID:9889131[2]

TAS: Traceable Author Statement

F

From MGI

GO:0005515

protein binding

MGI:MGI:1860653
PMID:10866835[3]

IPI: Inferred from Physical Interaction

UniProtKB:Q9CWT0

F

From MGI

GO:0005576

extracellular region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From MGI

GO:0005576

extracellular region

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR005817
InterPro:IPR009143

C

From MGI

GO:0005578

proteinaceous extracellular matrix

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0272

C

From MGI

GO:0005615

extracellular space

MGI:MGI:4459044

PANTHER:PTHR12027

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:4459044

PANTHER:PTHR12027

C

From MGI

GO:0007165

signal transduction

MGI:MGI:1327700
PMID:9889131[2]

TAS: Traceable Author Statement

P

From MGI

GO:0007267

cell-cell signaling

MGI:MGI:1327700
PMID:9889131[2]

TAS: Traceable Author Statement

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR005817
InterPro:IPR009143

P

From MGI

GO:0009798

axis specification

MGI:MGI:2178881
PMID:11948913[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0009887

organ morphogenesis

MGI:MGI:1327700
PMID:9889131[2]

TAS: Traceable Author Statement

P

From MGI

GO:0009952

anterior/posterior pattern specification

MGI:MGI:4459044

PANTHER:PTHR12027

P

From MGI

GO:0009986

cell surface

MGI:MGI:66576
PMID:8167409[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0010628

positive regulation of gene expression

MGI:MGI:2178087
PMID:11973284[5]

IDA: Inferred from Direct Assay

P

From MGI

GO:0010628

positive regulation of gene expression

MGI:MGI:2178881
PMID:11948913[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0010628

positive regulation of gene expression

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9Y6F9

P

From MGI

GO:0016055

Wnt receptor signaling pathway

MGI:MGI:2178087
PMID:11973284[5]

IDA: Inferred from Direct Assay

P

From MGI

GO:0016055

Wnt receptor signaling pathway

MGI:MGI:2178881
PMID:11948913[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0031012

extracellular matrix

MGI:MGI:66576
PMID:8167409[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0042475

odontogenesis of dentin-containing tooth

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9Y6F9

P

From MGI

GO:0045893

positive regulation of transcription, DNA-dependent

MGI:MGI:1099602
PMID:9356179[6]

IDA: Inferred from Direct Assay

P

From MGI

GO:0060070

canonical Wnt receptor signaling pathway

MGI:MGI:4459044

PANTHER:PTHR12027

P

From MGI

GO:0060684

epithelial-mesenchymal cell signaling

MGI:MGI:2178881
PMID:11948913[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0070172

positive regulation of tooth mineralization

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9Y6F9

P

From MGI

GO:0072079

nephron tubule formation

MGI:MGI:2178881
PMID:11948913[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0072080

nephron tubule development

MGI:MGI:2178881
PMID:11948913[1]

IDA: Inferred from Direct Assay

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Itäranta P et al. (2002) Wnt-6 is expressed in the ureter bud and induces kidney tubule development in vitro. Genesis 32: 259-68 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Loureiro JJ (1999) The Wnts. Curr Biol 9: R4 PubMed GONUTS page
  3. Tanaka K et al. (2000) The evolutionarily conserved porcupine gene family is involved in the processing of the Wnt family. Eur J Biochem 267: 4300-11 PubMed GONUTS page
  4. 4.0 4.1 Smolich BD et al. (1993) Wnt family proteins are secreted and associated with the cell surface. Mol Biol Cell 4: 1267-75 PubMed GONUTS page
  5. 5.0 5.1 Laurikkala J et al. (2002) Regulation of hair follicle development by the TNF signal ectodysplasin and its receptor Edar. Development 129: 2541-53 PubMed GONUTS page
  6. Fan CM et al. (1997) A role for WNT proteins in induction of dermomyotome. Dev Biol 191: 160-5 PubMed GONUTS page
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