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MGI:Wnt5b

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Wnt5b ( synonyms: Wnt-5b )
Protein Name(s) wingless-related MMTV integration site 5B,
External Links
MGI MGI:98959

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:4459044

PANTHER:PTHR12027

P

From MGI

GO:0001525

angiogenesis

MGI:MGI:4459044

PANTHER:PTHR12027

P

From MGI

GO:0002062

chondrocyte differentiation

MGI:MGI:4459044

PANTHER:PTHR12027

P

From MGI

GO:0005102

receptor binding

MGI:MGI:1327700
PMID:9889131[1]

TAS: Traceable Author Statement

F

From MGI

GO:0005102

receptor binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9H1J7

F

From MGI

GO:0005110

frizzled-2 binding

MGI:MGI:4459044

PANTHER:PTHR12027

F

From MGI

GO:0005515

protein binding

MGI:MGI:1860653
PMID:10866835[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q9CWT0

F

From MGI

GO:0005576

extracellular region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From MGI

GO:0005576

extracellular region

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR005817

C

From MGI

GO:0005578

proteinaceous extracellular matrix

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0272

C

From MGI

GO:0005615

extracellular space

MGI:MGI:4459044

PANTHER:PTHR12027

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:4459044

PANTHER:PTHR12027

C

From MGI

GO:0007165

signal transduction

MGI:MGI:1327700
PMID:9889131[1]

TAS: Traceable Author Statement

P

From MGI

GO:0007223

Wnt receptor signaling pathway, calcium modulating pathway

MGI:MGI:4459044

PANTHER:PTHR12027

P

From MGI

GO:0007267

cell-cell signaling

MGI:MGI:1327700
PMID:9889131[1]

TAS: Traceable Author Statement

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR005817

P

From MGI

GO:0009887

organ morphogenesis

MGI:MGI:1327700
PMID:9889131[1]

TAS: Traceable Author Statement

P

From MGI

GO:0009950

dorsal/ventral axis specification

MGI:MGI:4459044

PANTHER:PTHR12027

P

From MGI

GO:0009952

anterior/posterior pattern specification

MGI:MGI:4459044

PANTHER:PTHR12027

P

From MGI

GO:0009986

cell surface

MGI:MGI:66576
PMID:8167409[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0016055

Wnt receptor signaling pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9H1J7

P

From MGI

GO:0030335

positive regulation of cell migration

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9H1J7

P

From MGI

GO:0031012

extracellular matrix

MGI:MGI:66576
PMID:8167409[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0031018

endocrine pancreas development

MGI:MGI:4459044

PANTHER:PTHR12027

P

From MGI

GO:0042074

cell migration involved in gastrulation

MGI:MGI:4459044

PANTHER:PTHR12027

P

From MGI

GO:0045600

positive regulation of fat cell differentiation

MGI:MGI:3575460
PMID:15796911[4]

IGI: Inferred from Genetic Interaction

MGI:MGI:98956

P

From MGI

GO:0060027

convergent extension involved in gastrulation

MGI:MGI:4459044

PANTHER:PTHR12027

P

From MGI

GO:0060028

convergent extension involved in axis elongation

MGI:MGI:4459044

PANTHER:PTHR12027

P

From MGI

GO:0060541

respiratory system development

MGI:MGI:4459044

PANTHER:PTHR12027

P

From MGI

GO:0090090

negative regulation of canonical Wnt receptor signaling pathway

MGI:MGI:3575460
PMID:15796911[4]

IGI: Inferred from Genetic Interaction

MGI:MGI:98956

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Loureiro JJ (1999) The Wnts. Curr Biol 9: R4 PubMed GONUTS page
  2. Tanaka K et al. (2000) The evolutionarily conserved porcupine gene family is involved in the processing of the Wnt family. Eur J Biochem 267: 4300-11 PubMed GONUTS page
  3. 3.0 3.1 Smolich BD et al. (1993) Wnt family proteins are secreted and associated with the cell surface. Mol Biol Cell 4: 1267-75 PubMed GONUTS page
  4. 4.0 4.1 Kanazawa A et al. (2005) Wnt5b partially inhibits canonical Wnt/beta-catenin signaling pathway and promotes adipogenesis in 3T3-L1 preadipocytes. Biochem Biophys Res Commun 330: 505-10 PubMed GONUTS page
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