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MGI:Wnt11
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Wnt11 | |
| Protein Name(s) | wingless-related MMTV integration site 11, | |
| External Links | ||
| MGI | MGI:101948 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
MGI:MGI:4459044 |
PANTHER:PTHR12027 |
P |
From MGI |
|||
| GO:0001649 |
osteoblast differentiation |
MGI:MGI:3850932 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:88177 |
P |
From MGI |
||
| GO:0001649 |
osteoblast differentiation |
MGI:MGI:3850932 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:88177 |
P |
From MGI |
||
| GO:0001664 |
G-protein coupled receptor binding |
MGI:MGI:4459044 |
PANTHER:PTHR12027 |
F |
From MGI |
|||
| GO:0001822 |
kidney development |
MGI:MGI:4949995 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0001934 |
positive regulation of protein phosphorylation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0003151 |
outflow tract morphogenesis |
MGI:MGI:3759355 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2665014 |
P |
From MGI |
||
| GO:0005099 |
Ras GTPase activator activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005102 |
receptor binding |
MGI:MGI:1327700 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3814781 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005576 |
extracellular region |
MGI:MGI:3772496 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005578 |
proteinaceous extracellular matrix |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0272 |
C |
From MGI |
||
| GO:0005615 |
extracellular space |
MGI:MGI:4459044 |
PANTHER:PTHR12027 |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:3772496 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:4459044 |
PANTHER:PTHR12027 |
C |
From MGI |
|||
| GO:0006468 |
protein phosphorylation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007165 |
signal transduction |
MGI:MGI:1327700 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0007267 |
cell-cell signaling |
MGI:MGI:1327700 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007492 |
endoderm development |
MGI:MGI:4459044 |
PANTHER:PTHR12027 |
P |
From MGI |
|||
| GO:0009798 |
axis specification |
MGI:MGI:4459044 |
PANTHER:PTHR12027 |
P |
From MGI |
|||
| GO:0009887 |
organ morphogenesis |
MGI:MGI:1327700 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0009952 |
anterior/posterior pattern specification |
MGI:MGI:4459044 |
PANTHER:PTHR12027 |
P |
From MGI |
|||
| GO:0010628 |
positive regulation of gene expression |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016055 |
Wnt receptor signaling pathway |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0879 |
P |
From MGI |
||
| GO:0016055 |
Wnt receptor signaling pathway |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0030282 |
bone mineralization |
MGI:MGI:3850932 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:88177 |
P |
From MGI |
||
| GO:0030295 |
protein kinase activator activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0030308 |
negative regulation of cell growth |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030335 |
positive regulation of cell migration |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030336 |
negative regulation of cell migration |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0031012 |
extracellular matrix |
MGI:MGI:82099 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0032320 |
positive regulation of Ras GTPase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0032915 |
positive regulation of transforming growth factor beta2 production |
MGI:MGI:3759355 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2665014 |
P |
From MGI |
||
| GO:0034394 |
protein localization at cell surface |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0035567 |
non-canonical Wnt receptor signaling pathway |
MGI:MGI:3759355 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2665014 |
P |
From MGI |
||
| GO:0043065 |
positive regulation of apoptotic process |
MGI:MGI:3775898 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0043066 |
negative regulation of apoptotic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0044212 |
transcription regulatory region DNA binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045893 |
positive regulation of transcription, DNA-dependent |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0048844 |
artery morphogenesis |
MGI:MGI:3759355 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2665014 |
P |
From MGI |
||
| GO:0051496 |
positive regulation of stress fiber assembly |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0060021 |
palate development |
MGI:MGI:3775898 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0060021 |
palate development |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0060070 |
canonical Wnt receptor signaling pathway |
MGI:MGI:3850932 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0060412 |
ventricular septum morphogenesis |
MGI:MGI:3759355 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2665014 |
P |
From MGI |
||
| GO:0060548 |
negative regulation of cell death |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0061101 |
neuroendocrine cell differentiation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0070830 |
tight junction assembly |
MGI:MGI:3759355 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2665014 |
P |
From MGI |
||
| GO:0072201 |
negative regulation of mesenchymal cell proliferation |
MGI:MGI:3775898 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0090037 |
positive regulation of protein kinase C signaling cascade |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0090090 |
negative regulation of canonical Wnt receptor signaling pathway |
MGI:MGI:3772496 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0090090 |
negative regulation of canonical Wnt receptor signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0090272 |
negative regulation of fibroblast growth factor production |
MGI:MGI:3775898 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Friedman MS et al. (2009) Wnt11 promotes osteoblast maturation and mineralization through R-spondin 2. J Biol Chem 284: 14117-25 PubMed GONUTS page
- ↑ Nie X et al. (2011) Six1 regulates Grem1 expression in the metanephric mesenchyme to initiate branching morphogenesis. Dev Biol 352: 141-51 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 Zhou W et al. (2007) Modulation of morphogenesis by noncanonical Wnt signaling requires ATF/CREB family-mediated transcriptional activation of TGFbeta2. Nat Genet 39: 1225-34 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Loureiro JJ (1999) The Wnts. Curr Biol 9: R4 PubMed GONUTS page
- ↑ Yamamoto S et al. (2008) Cthrc1 selectively activates the planar cell polarity pathway of Wnt signaling by stabilizing the Wnt-receptor complex. Dev Cell 15: 23-36 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 Ouji Y et al. (2008) Wnt-10b, uniquely among Wnts, promotes epithelial differentiation and shaft growth. Biochem Biophys Res Commun 367: 299-304 PubMed GONUTS page
- ↑ Christiansen JH et al. (1996) Murine WNT11 is a secreted glycoprotein that morphologically transforms mammary epithelial cells. Oncogene 12: 2705-11 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 8.3 Lee JM et al. (2008) Wnt11/Fgfr1b cross-talk modulates the fate of cells in palate development. Dev Biol 314: 341-50 PubMed GONUTS page
