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MGI:Wnt1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Wnt1 ( synonyms: Int-1, Wnt-1 )
Protein Name(s) wingless-related MMTV integration site 1,
External Links
MGI MGI:98953

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:4459044

PANTHER:PTHR12027

P

From MGI

GO:0000578

embryonic axis specification

MGI:MGI:4822553
PMID:2534596[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0001658

branching involved in ureteric bud morphogenesis

MGI:MGI:3588895
PMID:16054034[2]

IGI: Inferred from Genetic Interaction

MGI:MGI:1197020

P

From MGI

GO:0001934

positive regulation of protein phosphorylation

MGI:MGI:3045675
PMID:15143170[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0005102

receptor binding

MGI:MGI:1327700
PMID:9889131[4]

TAS: Traceable Author Statement

F

From MGI

GO:0005110

frizzled-2 binding

MGI:MGI:4459044

PANTHER:PTHR12027

F

From MGI

GO:0005125

cytokine activity

MGI:MGI:4456962
PMID:10557084[5]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005515

protein binding

MGI:MGI:1860653
PMID:10866835[6]

IPI: Inferred from Physical Interaction

UniProtKB:Q9CWT0

F

From MGI

GO:0005515

protein binding

MGI:MGI:2178168
PMID:11956231[7]

IPI: Inferred from Physical Interaction

UniProtKB:Q91VN0

F

From MGI

GO:0005515

protein binding

MGI:MGI:3510085
PMID:15454084[8]

IPI: Inferred from Physical Interaction

UniProtKB:Q01887

F

From MGI

GO:0005515

protein binding

MGI:MGI:3603992
PMID:16126904[9]

IPI: Inferred from Physical Interaction

UniProtKB:O88572

F

From MGI

GO:0005515

protein binding

MGI:MGI:3718804
PMID:17690294[10]

IPI: Inferred from Physical Interaction

UniProtKB:O35082

F

From MGI

GO:0005515

protein binding

MGI:MGI:4397730
PMID:19841259[11]

IPI: Inferred from Physical Interaction

UniProtKB:Q6DID7

F

From MGI

GO:0005515

protein binding

MGI:MGI:4839462
PMID:11029007[12]

IPI: Inferred from Physical Interaction

UniProtKB:O75581

F

From MGI

GO:0005576

extracellular region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From MGI

GO:0005576

extracellular region

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR005817
InterPro:IPR009139

C

From MGI

GO:0005578

proteinaceous extracellular matrix

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0272

C

From MGI

GO:0005615

extracellular space

MGI:MGI:4459044

PANTHER:PTHR12027

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04628

C

From MGI

GO:0005769

early endosome

MGI:MGI:4459044

PANTHER:PTHR12027

C

From MGI

GO:0005770

late endosome

MGI:MGI:4459044

PANTHER:PTHR12027

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:4459044

PANTHER:PTHR12027

C

From MGI

GO:0007165

signal transduction

MGI:MGI:1327700
PMID:9889131[4]

TAS: Traceable Author Statement

P

From MGI

GO:0007223

Wnt receptor signaling pathway, calcium modulating pathway

MGI:MGI:4459044

PANTHER:PTHR12027

P

From MGI

GO:0007267

cell-cell signaling

MGI:MGI:1327700
PMID:9889131[4]

TAS: Traceable Author Statement

P

From MGI

GO:0007267

cell-cell signaling

MGI:MGI:4456962
PMID:10557084[5]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR005817
InterPro:IPR009139

P

From MGI

GO:0007520

myoblast fusion

MGI:MGI:3522557
PMID:15282335[13]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007520

myoblast fusion

MGI:MGI:3522557
PMID:15282335[13]

IGI: Inferred from Genetic Interaction

MGI:MGI:96573

P

From MGI

GO:0008284

positive regulation of cell proliferation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04628

P

From MGI

GO:0008284

positive regulation of cell proliferation

MGI:MGI:87698
PMID:9160667[14]

IDA: Inferred from Direct Assay

P

From MGI

GO:0009887

organ morphogenesis

MGI:MGI:1327700
PMID:9889131[4]

TAS: Traceable Author Statement

P

From MGI

GO:0009986

cell surface

MGI:MGI:81949
PMID:8710372[15]

IDA: Inferred from Direct Assay

C

From MGI

GO:0010592

positive regulation of lamellipodium assembly

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04628

P

From MGI

GO:0010812

negative regulation of cell-substrate adhesion

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04628

P

From MGI

GO:0014902

myotube differentiation

MGI:MGI:3522557
PMID:15282335[13]

IGI: Inferred from Genetic Interaction

MGI:MGI:96573

P

From MGI

GO:0016055

Wnt receptor signaling pathway

MGI:MGI:3619629
PMID:16207730[16]

IDA: Inferred from Direct Assay

P

From MGI

GO:0016055

Wnt receptor signaling pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04628

P

From MGI

GO:0019904

protein domain specific binding

MGI:MGI:3510085
PMID:15454084[8]

IPI: Inferred from Physical Interaction

UniProtKB:Q01887

F

From MGI

GO:0021527

spinal cord association neuron differentiation

MGI:MGI:2176385
PMID:11877374[17]

IGI: Inferred from Genetic Interaction

MGI:MGI:98956

P

From MGI

GO:0021536

diencephalon development

MGI:MGI:3772426
PMID:18094027[18]

IGI: Inferred from Genetic Interaction

MGI:MGI:102764

P

From MGI

GO:0021551

central nervous system morphogenesis

MGI:MGI:1931348
PMID:2202907[19]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0021588

cerebellum formation

MGI:MGI:1931348
PMID:2202907[19]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0021592

fourth ventricle development

MGI:MGI:4459044

PANTHER:PTHR12027

P

From MGI

GO:0021797

forebrain anterior/posterior pattern specification

MGI:MGI:3772426
PMID:18094027[18]

IGI: Inferred from Genetic Interaction

MGI:MGI:102764

P

From MGI

GO:0022004

midbrain-hindbrain boundary maturation during brain development

MGI:MGI:76584
PMID:8555108[20]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1856382

P

From MGI

GO:0022037

metencephalon development

MGI:MGI:59176
PMID:2205396[21]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857490

P

From MGI

GO:0022408

negative regulation of cell-cell adhesion

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04628

P

From MGI

GO:0030509

BMP signaling pathway

MGI:MGI:4429763
PMID:19850029[22]

ISO: Inferred from Sequence Orthology

UniProtKB:Q91029

P

From MGI

GO:0030512

negative regulation of transforming growth factor beta receptor signaling pathway

MGI:MGI:3628833
PMID:16601693[23]

IDA: Inferred from Direct Assay

P

From MGI

GO:0030579

ubiquitin-dependent SMAD protein catabolic process

MGI:MGI:3628833
PMID:16601693[23]

IDA: Inferred from Direct Assay

P

From MGI

GO:0030901

midbrain development

MGI:MGI:1931348
PMID:2202907[19]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0030901

midbrain development

MGI:MGI:59176
PMID:2205396[21]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857490

P

From MGI

GO:0030917

midbrain-hindbrain boundary development

MGI:MGI:59176
PMID:2205396[21]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857490

P

From MGI

GO:0031100

organ regeneration

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001099184

P

From MGI

GO:0033077

T cell differentiation in thymus

MGI:MGI:1929591
PMID:11265645[24]

IDA: Inferred from Direct Assay

P

From MGI

GO:0035284

brain segmentation

MGI:MGI:4459044

PANTHER:PTHR12027

P

From MGI

GO:0042472

inner ear morphogenesis

MGI:MGI:3582112
PMID:15961523[25]

IGI: Inferred from Genetic Interaction

MGI:MGI:98956

P

From MGI

GO:0042770

signal transduction in response to DNA damage

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04628

P

From MGI

GO:0043066

negative regulation of apoptotic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04628

P

From MGI

GO:0043568

positive regulation of insulin-like growth factor receptor signaling pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04628

P

From MGI

GO:0044212

transcription regulatory region DNA binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04628

F

From MGI

GO:0044336

canonical Wnt receptor signaling pathway involved in negative regulation of apoptotic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04628

P

From MGI

GO:0045121

membrane raft

MGI:MGI:4459044

PANTHER:PTHR12027

C

From MGI

GO:0045599

negative regulation of fat cell differentiation

MGI:MGI:3574150
PMID:15728361[26]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045599

negative regulation of fat cell differentiation

MGI:MGI:3758508
PMID:10937998[27]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045599

negative regulation of fat cell differentiation

MGI:MGI:3758508
PMID:10937998[27]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0045747

positive regulation of Notch signaling pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04628

P

From MGI

GO:0045893

positive regulation of transcription, DNA-dependent

MGI:MGI:1099602
PMID:9356179[28]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045893

positive regulation of transcription, DNA-dependent

MGI:MGI:4441133
PMID:12937339[29]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045893

positive regulation of transcription, DNA-dependent

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04628

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:1306711
PMID:9769173[30]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:3512829
PMID:15574752[31]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:3512829
PMID:15574752[31]

IGI: Inferred from Genetic Interaction

MGI:MGI:1933114
MGI:MGI:1919385
MGI:MGI:1924828

P

From MGI

GO:0048146

positive regulation of fibroblast proliferation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04628

P

From MGI

GO:0048332

mesoderm morphogenesis

MGI:MGI:4459044

PANTHER:PTHR12027

P

From MGI

GO:0048663

neuron fate commitment

MGI:MGI:3611719
PMID:16339193[32]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2153126

P

From MGI

GO:0048664

neuron fate determination

MGI:MGI:3611719
PMID:16339193[32]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3046939

P

From MGI

GO:0051091

positive regulation of sequence-specific DNA binding transcription factor activity

MGI:MGI:3621833
PMID:15035989[33]

IDA: Inferred from Direct Assay

P

From MGI

GO:0060061

Spemann organizer formation

MGI:MGI:893982
PMID:9192640[34]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0060070

canonical Wnt receptor signaling pathway

MGI:MGI:1261652
PMID:9652750[35]

IDA: Inferred from Direct Assay

P

From MGI

GO:0060070

canonical Wnt receptor signaling pathway

MGI:MGI:1929591
PMID:11265645[24]

IDA: Inferred from Direct Assay

P

From MGI

GO:0060070

canonical Wnt receptor signaling pathway

MGI:MGI:3045540
PMID:15064719[36]

IDA: Inferred from Direct Assay

P

From MGI

GO:0060070

canonical Wnt receptor signaling pathway

MGI:MGI:3045675
PMID:15143170[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:1329040

P

From MGI

GO:0060070

canonical Wnt receptor signaling pathway

MGI:MGI:3522557
PMID:15282335[13]

IDA: Inferred from Direct Assay

P

From MGI

GO:0060070

canonical Wnt receptor signaling pathway

MGI:MGI:3664518
PMID:16543246[37]

IDA: Inferred from Direct Assay

P

From MGI

GO:0060070

canonical Wnt receptor signaling pathway

MGI:MGI:3758508
PMID:10937998[27]

IDA: Inferred from Direct Assay

P

From MGI

GO:0060070

canonical Wnt receptor signaling pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04628

P

From MGI

GO:0060070

canonical Wnt receptor signaling pathway

MGI:MGI:4835152
PMID:15265686[38]

IDA: Inferred from Direct Assay

P

From MGI

GO:0060070

canonical Wnt receptor signaling pathway

MGI:MGI:5009183
PMID:12121999[39]

IDA: Inferred from Direct Assay

P

From MGI

GO:0061184

positive regulation of dermatome development

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04628

P

From MGI

GO:0070365

hepatocyte differentiation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001099184

P

From MGI

GO:0070365

hepatocyte differentiation

MGI:MGI:4459044

PANTHER:PTHR12027

P

From MGI

GO:0071425

hemopoietic stem cell proliferation

MGI:MGI:87698
PMID:9160667[14]

IDA: Inferred from Direct Assay

P

From MGI

GO:0090344

negative regulation of cell aging

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04628

P

From MGI

GO:2000002

negative regulation of DNA damage checkpoint

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04628

P

From MGI

GO:2000059

negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

MGI:MGI:3628833
PMID:16601693[23]

IDA: Inferred from Direct Assay

P

From MGI


edit table

Notes

References

See Help:References for how to manage references in GONUTS.
  1. ↑ McMahon AP & Moon RT (1989) int-1--a proto-oncogene involved in cell signalling. Development 107 Suppl: 161-7 PubMed GONUTS page
  2. ↑ Carroll TJ et al. (2005) Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system. Dev Cell 9: 283-92 PubMed GONUTS page
  3. ↑ 3.0 3.1 González-Sancho JM et al. (2004) Wnt proteins induce dishevelled phosphorylation via an LRP5/6- independent mechanism, irrespective of their ability to stabilize beta-catenin. Mol Cell Biol 24: 4757-68 PubMed GONUTS page
  4. ↑ 4.0 4.1 4.2 4.3 Loureiro JJ (1999) The Wnts. Curr Biol 9: R4 PubMed GONUTS page
  5. ↑ 5.0 5.1 Gazit A et al. (1999) Human frizzled 1 interacts with transforming Wnts to transduce a TCF dependent transcriptional response. Oncogene 18: 5959-66 PubMed GONUTS page
  6. ↑ Tanaka K et al. (2000) The evolutionarily conserved porcupine gene family is involved in the processing of the Wnt family. Eur J Biochem 267: 4300-11 PubMed GONUTS page
  7. ↑ Kato M et al. (2002) Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor. J Cell Biol 157: 303-14 PubMed GONUTS page
  8. ↑ 8.0 8.1 Lu W et al. (2004) Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth. Cell 119: 97-108 PubMed GONUTS page
  9. ↑ Carter M et al. (2005) Crooked tail (Cd) model of human folate-responsive neural tube defects is mutated in Wnt coreceptor lipoprotein receptor-related protein 6. Proc Natl Acad Sci U S A 102: 12843-8 PubMed GONUTS page
  10. ↑ Liu H et al. (2007) Augmented Wnt signaling in a mammalian model of accelerated aging. Science 317: 803-6 PubMed GONUTS page
  11. ↑ Fu J et al. (2009) Reciprocal regulation of Wnt and Gpr177/mouse Wntless is required for embryonic axis formation. Proc Natl Acad Sci U S A 106: 18598-603 PubMed GONUTS page
  12. ↑ Tamai K et al. (2000) LDL-receptor-related proteins in Wnt signal transduction. Nature 407: 530-5 PubMed GONUTS page
  13. ↑ 13.0 13.1 13.2 13.3 Rochat A et al. (2004) Insulin and wnt1 pathways cooperate to induce reserve cell activation in differentiation and myotube hypertrophy. Mol Biol Cell 15: 4544-55 PubMed GONUTS page
  14. ↑ 14.0 14.1 Austin TW et al. (1997) A role for the Wnt gene family in hematopoiesis: expansion of multilineage progenitor cells. Blood 89: 3624-35 PubMed GONUTS page
  15. ↑ Schryver B et al. (1996) Properties of Wnt-1 protein that enable cell surface association. Oncogene 13: 333-42 PubMed GONUTS page
  16. ↑ Johnson EB et al. (2005) Abnormal development of the apical ectodermal ridge and polysyndactyly in Megf7-deficient mice. Hum Mol Genet 14: 3523-38 PubMed GONUTS page
  17. ↑ Muroyama Y et al. (2002) Wnt signaling plays an essential role in neuronal specification of the dorsal spinal cord. Genes Dev 16: 548-53 PubMed GONUTS page
  18. ↑ 18.0 18.1 Lavado A et al. (2008) Six3 inactivation causes progressive caudalization and aberrant patterning of the mammalian diencephalon. Development 135: 441-50 PubMed GONUTS page
  19. ↑ 19.0 19.1 19.2 Thomas KR & Capecchi MR (1990) Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development. Nature 346: 847-50 PubMed GONUTS page
  20. ↑ Bally-Cuif L et al. (1995) Involvement of Wnt-1 in the formation of the mes/metencephalic boundary. Mech Dev 53: 23-34 PubMed GONUTS page
  21. ↑ 21.0 21.1 21.2 McMahon AP & Bradley A (1990) The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain. Cell 62: 1073-85 PubMed GONUTS page
  22. ↑ Misra K & Matise MP (2010) A critical role for sFRP proteins in maintaining caudal neural tube closure in mice via inhibition of BMP signaling. Dev Biol 337: 74-83 PubMed GONUTS page
  23. ↑ 23.0 23.1 23.2 Liu W et al. (2006) Axin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia. EMBO J 25: 1646-58 PubMed GONUTS page
  24. ↑ 24.0 24.1 Staal FJ et al. (2001) Wnt signaling is required for thymocyte development and activates Tcf-1 mediated transcription. Eur J Immunol 31: 285-93 PubMed GONUTS page
  25. ↑ Riccomagno MM et al. (2005) Wnt-dependent regulation of inner ear morphogenesis is balanced by the opposing and supporting roles of Shh. Genes Dev 19: 1612-23 PubMed GONUTS page
  26. ↑ Bennett CN et al. (2005) Regulation of osteoblastogenesis and bone mass by Wnt10b. Proc Natl Acad Sci U S A 102: 3324-9 PubMed GONUTS page
  27. ↑ 27.0 27.1 27.2 Ross SE et al. (2000) Inhibition of adipogenesis by Wnt signaling. Science 289: 950-3 PubMed GONUTS page
  28. ↑ Fan CM et al. (1997) A role for WNT proteins in induction of dermomyotome. Dev Biol 191: 160-5 PubMed GONUTS page
  29. ↑ Ohira T et al. (2003) WNT7a induces E-cadherin in lung cancer cells. Proc Natl Acad Sci U S A 100: 10429-34 PubMed GONUTS page
  30. ↑ Dassule HR & McMahon AP (1998) Analysis of epithelial-mesenchymal interactions in the initial morphogenesis of the mammalian tooth. Dev Biol 202: 215-27 PubMed GONUTS page
  31. ↑ 31.0 31.1 Adachi S et al. (2004) Role of a BCL9-related beta-catenin-binding protein, B9L, in tumorigenesis induced by aberrant activation of Wnt signaling. Cancer Res 64: 8496-501 PubMed GONUTS page
  32. ↑ 32.0 32.1 Prakash N et al. (2006) A Wnt1-regulated genetic network controls the identity and fate of midbrain-dopaminergic progenitors in vivo. Development 133: 89-98 PubMed GONUTS page
  33. ↑ Xu Q et al. (2004) Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair. Cell 116: 883-95 PubMed GONUTS page
  34. ↑ Finch PW et al. (1997) Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action. Proc Natl Acad Sci U S A 94: 6770-5 PubMed GONUTS page
  35. ↑ Bafico A et al. (1998) Characterization of Wnt-1 and Wnt-2 induced growth alterations and signaling pathways in NIH3T3 fibroblasts. Oncogene 16: 2819-25 PubMed GONUTS page
  36. ↑ Brennan K et al. (2004) Truncated mutants of the putative Wnt receptor LRP6/Arrow can stabilize beta-catenin independently of Frizzled proteins. Oncogene 23: 4873-84 PubMed GONUTS page
  37. ↑ Nam JS et al. (2006) Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression. J Biol Chem 281: 13247-57 PubMed GONUTS page
  38. ↑ Lyons JP et al. (2004) Wnt-4 activates the canonical beta-catenin-mediated Wnt pathway and binds Frizzled-6 CRD: functional implications of Wnt/beta-catenin activity in kidney epithelial cells. Exp Cell Res 298: 369-87 PubMed GONUTS page
  39. ↑ Holmen SL et al. (2002) A novel set of Wnt-Frizzled fusion proteins identifies receptor components that activate beta -catenin-dependent signaling. J Biol Chem 277: 34727-35 PubMed GONUTS page
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