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MGI:Wee2

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Wee2 ( synonyms: LOC381759, Wee1b )
Protein Name(s) WEE1 homolog 2 (S. pombe),
External Links
MGI MGI:3027899

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From MGI

GO:0000287

magnesium ion binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR017164

F

From MGI

GO:0004672

protein kinase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000719

F

From MGI

GO:0004674

protein serine/threonine kinase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR008271

F

From MGI

GO:0004713

protein tyrosine kinase activity

MGI:MGI:3604224
PMID:16169490[1]

TAS: Traceable Author Statement

F

From MGI

GO:0004713

protein tyrosine kinase activity

MGI:MGI:4948986
PMID:21454751[2]

TAS: Traceable Author Statement

F

From MGI

GO:0004715

non-membrane spanning protein tyrosine kinase activity

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:2.7.10.2

F

From MGI

GO:0004715

non-membrane spanning protein tyrosine kinase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR017164

F

From MGI

GO:0005524

ATP binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

From MGI

GO:0005524

ATP binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR017441

F

From MGI

GO:0005634

nucleus

MGI:MGI:4421461
PMID:20083600[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P0C1S8

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4421461
PMID:20083600[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P0C1S8

C

From MGI

GO:0005813

centrosome

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P0C1S8

C

From MGI

GO:0007067

mitosis

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR017164

P

From MGI

GO:0007126

meiosis

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0469

P

From MGI

GO:0007128

meiotic prophase I

MGI:MGI:3604224
PMID:16169490[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0007137

meiotic metaphase II

MGI:MGI:4948986
PMID:21454751[2]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0007143

female meiosis

MGI:MGI:3604224
PMID:16169490[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0007343

egg activation

MGI:MGI:4948986
PMID:21454751[2]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0016301

kinase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

F

From MGI

GO:0016310

phosphorylation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

P

From MGI

GO:0016740

transferase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

From MGI

GO:0016772

transferase activity, transferring phosphorus-containing groups

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011009

F

From MGI

GO:0035038

female pronucleus assembly

MGI:MGI:4948986
PMID:21454751[2]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI

GO:0060283

negative regulation of oocyte development

MGI:MGI:3604224
PMID:16169490[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0060631

regulation of meiosis I

MGI:MGI:3604224
PMID:16169490[1]

IMP: Inferred from Mutant Phenotype

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Han SJ et al. (2005) Wee1B is an oocyte-specific kinase involved in the control of meiotic arrest in the mouse. Curr Biol 15: 1670-6 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Oh JS et al. (2011) Protein tyrosine kinase Wee1B is essential for metaphase II exit in mouse oocytes. Science 332: 462-5 PubMed GONUTS page
  3. 3.0 3.1 Oh JS et al. (2010) Wee1B, Myt1, and Cdc25 function in distinct compartments of the mouse oocyte to control meiotic resumption. J Cell Biol 188: 199-207 PubMed GONUTS page
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