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MGI:Wasl

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Wasl ( synonyms: N-WASP )
Protein Name(s) Wiskott-Aldrich syndrome-like (human),
External Links
MGI MGI:1920428

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000139

Golgi membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08816

C

From MGI

GO:0003779

actin binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0009

F

From MGI

GO:0003779

actin binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003124

F

From MGI

GO:0005083

small GTPase regulator activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011026

F

From MGI

GO:0005515

protein binding

MGI:MGI:1929303
PMID:11082044[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q61644
UniProtKB:Q9WVE8
UniProtKB:Q99JB8

F

From MGI

GO:0005515

protein binding

MGI:MGI:3056883
PMID:15247266[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q99JY9

F

From MGI

GO:0005634

nucleus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From MGI

GO:0005730

nucleolus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O00401

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:2156091
PMID:11559594[3]

IC: Inferred by Curator

GO:0045010

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O00401

C

From MGI

GO:0005856

cytoskeleton

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0206

C

From MGI

GO:0006351

transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From MGI

GO:0006461

protein complex assembly

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011026

P

From MGI

GO:0008154

actin polymerization or depolymerization

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011026

P

From MGI

GO:0009617

response to bacterium

MGI:MGI:2156091
PMID:11559594[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2159338

P

From MGI

GO:0015629

actin cytoskeleton

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011026

C

From MGI

GO:0030027

lamellipodium

MGI:MGI:3046012
PMID:15148305[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0030036

actin cytoskeleton organization

MGI:MGI:5293241
PMID:21874009[5]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0030478

actin cap

MGI:MGI:5293241
PMID:21874009[5]

IDA: Inferred from Direct Assay

C

From MGI

GO:0034629

cellular protein complex localization

MGI:MGI:5293241
PMID:21874009[5]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0045010

actin nucleation

MGI:MGI:2156091
PMID:11559594[3]

TAS: Traceable Author Statement

P

From MGI

GO:0050790

regulation of catalytic activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011026

P

From MGI

GO:0051653

spindle localization

MGI:MGI:5293241
PMID:21874009[5]

IMP: Inferred from Mutant Phenotype

P

From MGI

NOT

GO:0030031

cell projection assembly

MGI:MGI:2156091
PMID:11559594[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2159338

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Modregger J et al. (2000) All three PACSIN isoforms bind to endocytic proteins and inhibit endocytosis. J Cell Sci 113 Pt 24: 4511-21 PubMed GONUTS page
  2. Guilherme A et al. (2004) Role of EHD1 and EHBP1 in perinuclear sorting and insulin-regulated GLUT4 recycling in 3T3-L1 adipocytes. J Biol Chem 279: 40062-75 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Lommel S et al. (2001) Actin pedestal formation by enteropathogenic Escherichia coli and intracellular motility of Shigella flexneri are abolished in N-WASP-defective cells. EMBO Rep 2: 850-7 PubMed GONUTS page
  4. Tanoue T & Takeichi M (2004) Mammalian Fat1 cadherin regulates actin dynamics and cell-cell contact. J Cell Biol 165: 517-28 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 Yi K et al. (2011) Dynamic maintenance of asymmetric meiotic spindle position through Arp2/3-complex-driven cytoplasmic streaming in mouse oocytes. Nat Cell Biol 13: 1252-8 PubMed GONUTS page
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