GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
MGI:Was
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Was ( synonyms: U42471, Wasp ) | |
| Protein Name(s) | Wiskott-Aldrich syndrome homolog (human), | |
| External Links | ||
| MGI | MGI:105059 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003779 |
actin binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005083 |
small GTPase regulator activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:1927282 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3528803 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3688344 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4834990 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:2387810 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0963 |
C |
From MGI |
||
| GO:0005856 |
cytoskeleton |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0206 |
C |
From MGI |
||
| GO:0006461 |
protein complex assembly |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0006955 |
immune response |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008154 |
actin polymerization or depolymerization |
MGI:MGI:2387810 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0012506 |
vesicle membrane |
MGI:MGI:2387810 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0015629 |
actin cytoskeleton |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0016197 |
endosome transport |
MGI:MGI:2387810 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0030041 |
actin filament polymerization |
MGI:MGI:2387810 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0030048 |
actin filament-based movement |
MGI:MGI:2387810 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0042110 |
T cell activation |
MGI:MGI:2388463 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1861707 |
P |
From MGI |
||
| GO:0042802 |
identical protein binding |
MGI:MGI:2387810 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0042802 |
identical protein binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0050790 |
regulation of catalytic activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Vignal E et al. (2000) Characterization of TCL, a new GTPase of the rho family related to TC10 andCcdc42. J Biol Chem 275: 36457-64 PubMed GONUTS page
- ↑ Round JL et al. (2005) Dlgh1 coordinates actin polymerization, synaptic T cell receptor and lipid raft aggregation, and effector function in T cells. J Exp Med 201: 419-30 PubMed GONUTS page
- ↑ Papin J & Subramaniam S (2004) Bioinformatics and cellular signaling. Curr Opin Biotechnol 15: 78-81 PubMed GONUTS page
- ↑ Ma T et al. (2008) Dramatic inhibition of osteoclast sealing ring formation and bone resorption in vitro by a WASP-peptide containing pTyr294 amino acid. J Mol Signal 3: 4 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 5.4 5.5 5.6 Benesch S et al. (2002) Phosphatidylinositol 4,5-biphosphate (PIP2)-induced vesicle movement depends on N-WASP and involves Nck, WIP, and Grb2. J Biol Chem 277: 37771-6 PubMed GONUTS page
- ↑ Krawczyk C et al. (2000) Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells. Immunity 13: 463-73 PubMed GONUTS page
