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MGI:Vwf

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Vwf
Protein Name(s) Von Willebrand factor homolog,
External Links
MGI MGI:98941

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001889

liver development

MGI:MGI:70957
PMID:7854452[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857656

P

From MGI

GO:0001890

placenta development

MGI:MGI:70957
PMID:7854452[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857656

P

From MGI

GO:0001948

glycoprotein binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04275

F

From MGI

GO:0002020

protease binding

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P04275

F

From MGI

GO:0005178

integrin binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04275

F

From MGI

GO:0005515

protein binding

MGI:MGI:3785344
PMID:18281502[2]

IPI: Inferred from Physical Interaction

UniProtKB:P55002

F

From MGI

GO:0005518

collagen binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04275

F

From MGI

GO:0005576

extracellular region

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04275

C

From MGI

GO:0005578

proteinaceous extracellular matrix

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0272

C

From MGI

GO:0005578

proteinaceous extracellular matrix

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR012011

C

From MGI

GO:0005783

endoplasmic reticulum

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04275

C

From MGI

GO:0007155

cell adhesion

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04275

P

From MGI

GO:0007596

blood coagulation

MGI:MGI:1276653
PMID:9689113[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2153009

P

From MGI

GO:0007596

blood coagulation

MGI:MGI:3709713
PMID:17380206[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2153009

P

From MGI

GO:0007596

blood coagulation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q62935

P

From MGI

GO:0007596

blood coagulation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04275

P

From MGI

GO:0007599

hemostasis

MGI:MGI:1276653
PMID:9689113[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2153009

P

From MGI

GO:0007599

hemostasis

MGI:MGI:1351542
PMID:11212329[5]

TAS: Traceable Author Statement

P

From MGI

GO:0007599

hemostasis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04275

P

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:3757618
PMID:8562500[6]

IDA: Inferred from Direct Assay

C

From MGI

GO:0019865

immunoglobulin binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04275

F

From MGI

GO:0030168

platelet activation

MGI:MGI:1861538
PMID:10930441[7]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2153009

P

From MGI

GO:0030168

platelet activation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q62935

P

From MGI

GO:0030168

platelet activation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04275

P

From MGI

GO:0031012

extracellular matrix

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q62935

C

From MGI

GO:0031012

extracellular matrix

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04275

C

From MGI

GO:0031589

cell-substrate adhesion

MGI:MGI:1927325
PMID:11071623[8]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2153009

P

From MGI

GO:0031589

cell-substrate adhesion

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04275

P

From MGI

GO:0033093

Weibel-Palade body

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04275

C

From MGI

GO:0042803

protein homodimerization activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04275

F

From MGI

GO:0047485

protein N-terminus binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04275

F

From MGI

GO:0051087

chaperone binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04275

F

From MGI

GO:0051260

protein homooligomerization

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04275

P

From MGI

NOT

GO:0030168

platelet activation

MGI:MGI:3709713
PMID:17380206[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2153009

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Schmidt C et al. (1995) Scatter factor/hepatocyte growth factor is essential for liver development. Nature 373: 699-702 PubMed GONUTS page
  2. Werneck CC et al. (2008) Mice lacking the extracellular matrix protein MAGP1 display delayed thrombotic occlusion following vessel injury. Blood 111: 4137-44 PubMed GONUTS page
  3. 3.0 3.1 Denis C et al. (1998) A mouse model of severe von Willebrand disease: defects in hemostasis and thrombosis. Proc Natl Acad Sci U S A 95: 9524-9 PubMed GONUTS page
  4. 4.0 4.1 Dubois C et al. (2007) Thrombin-initiated platelet activation in vivo is vWF independent during thrombus formation in a laser injury model. J Clin Invest 117: 953-60 PubMed GONUTS page
  5. Denis CV & Wagner DD (1999) Insights from von Willebrand disease animal models. Cell Mol Life Sci 56: 977-90 PubMed GONUTS page
  6. Aigner S et al. (1995) Heat stable antigen (mouse CD24) supports myeloid cell binding to endothelial and platelet P-selectin. Int Immunol 7: 1557-65 PubMed GONUTS page
  7. Ni H et al. (2000) Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogen. J Clin Invest 106: 385-92 PubMed GONUTS page
  8. André P et al. (2000) Platelets adhere to and translocate on von Willebrand factor presented by endothelium in stimulated veins. Blood 96: 3322-8 PubMed GONUTS page
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