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MGI:Vsx2
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Vsx2 ( synonyms: Chx10, Hox-10, Hox10 ) | |
| Protein Name(s) | visual system homeobox 2, | |
| External Links | ||
| MGI | MGI:88401 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003677 |
DNA binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0238 |
F |
From MGI |
||
| GO:0003677 |
DNA binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:1195383 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:1344237 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3575842 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3848562 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005730 |
nucleolus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:3575842 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:3848562 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0805 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0008284 |
positive regulation of cell proliferation |
MGI:MGI:79586 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856112 |
P |
From MGI |
||
| GO:0008285 |
negative regulation of cell proliferation |
MGI:MGI:3611606 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856112 |
P |
From MGI |
||
| GO:0043010 |
camera-type eye development |
MGI:MGI:3512656 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:104554 |
P |
From MGI |
||
| GO:0043565 |
sequence-specific DNA binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0045165 |
cell fate commitment |
MGI:MGI:3512656 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856112 |
P |
From MGI |
||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:3575842 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0060040 |
retinal bipolar neuron differentiation |
MGI:MGI:79586 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856112 |
P |
From MGI |
||
| GO:0060042 |
retina morphogenesis in camera-type eye |
MGI:MGI:3701027 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856112 |
P |
From MGI |
||
| GO:0060042 |
retina morphogenesis in camera-type eye |
MGI:MGI:79586 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856112 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Wiggan O et al. (1998) Interaction of the pRB-family proteins with factors containing paired-like homeodomains. Oncogene 16: 227-36 PubMed GONUTS page
- ↑ Arber S et al. (1999) Requirement for the homeobox gene Hb9 in the consolidation of motor neuron identity. Neuron 23: 659-74 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Knauer SK et al. (2005) Nuclear export is evolutionarily conserved in CVC paired-like homeobox proteins and influences protein stability, transcriptional activation, and extracellular secretion. Mol Cell Biol 25: 2573-82 PubMed GONUTS page
- ↑ 4.0 4.1 Rocha SF et al. (2009) Dll1 and Dll4 function sequentially in the retina and pV2 domain of the spinal cord to regulate neurogenesis and create cell diversity. Dev Biol 328: 54-65 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Burmeister M et al. (1996) Ocular retardation mouse caused by Chx10 homeobox null allele: impaired retinal progenitor proliferation and bipolar cell differentiation. Nat Genet 12: 376-84 PubMed GONUTS page
- ↑ Dhomen NS et al. (2006) Absence of chx10 causes neural progenitors to persist in the adult retina. Invest Ophthalmol Vis Sci 47: 386-96 PubMed GONUTS page
- ↑ 7.0 7.1 Horsford DJ et al. (2005) Chx10 repression of Mitf is required for the maintenance of mammalian neuroretinal identity. Development 132: 177-87 PubMed GONUTS page
- ↑ Morcillo J et al. (2006) Proper patterning of the optic fissure requires the sequential activity of BMP7 and SHH. Development 133: 3179-90 PubMed GONUTS page
