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MGI:Vkorc1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Vkorc1 ( synonyms: D7Wsu86e ) | |
| Protein Name(s) | vitamin K epoxide reductase complex, subunit 1, | |
| External Links | ||
| MGI | MGI:106442 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005783 |
endoplasmic reticulum |
MGI:MGI:2678901 |
ISA: Inferred from Sequence Alignment |
EMBL:AY423044 |
C |
From MGI |
||
| GO:0005792 |
microsome |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_976080 |
C |
From MGI |
||
| GO:0010243 |
response to organic nitrogen |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_976080 |
P |
From MGI |
||
| GO:0014070 |
response to organic cyclic compound |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_976080 |
P |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0016491 |
oxidoreductase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0560 |
F |
From MGI |
||
| GO:0017144 |
drug metabolic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030193 |
regulation of blood coagulation |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_976080 |
P |
From MGI |
||
| GO:0042371 |
vitamin K biosynthetic process |
MGI:MGI:2678901 |
ISA: Inferred from Sequence Alignment |
EMBL:AY423044 |
P |
From MGI |
||
| GO:0042373 |
vitamin K metabolic process |
MGI:MGI:3604816 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0046677 |
response to antibiotic |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_976080 |
P |
From MGI |
||
| GO:0047057 |
vitamin-K-epoxide reductase (warfarin-sensitive) activity |
MGI:MGI:3029617 |
ISA: Inferred from Sequence Alignment |
EMBL:AY423044 |
F |
From MGI |
||
| GO:0047057 |
vitamin-K-epoxide reductase (warfarin-sensitive) activity |
MGI:MGI:3604816 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0047058 |
vitamin-K-epoxide reductase (warfarin-insensitive) activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_976080 |
F |
From MGI |
||
| GO:0050820 |
positive regulation of coagulation |
MGI:MGI:3604816 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3605979 |
P |
From MGI |
||
|
contributes_to |
GO:0047057 |
vitamin-K-epoxide reductase (warfarin-sensitive) activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_976080 |
F |
From MGI |
|
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Liu YY et al. (2002) A targeted thyroid hormone receptor alpha gene dominant-negative mutation (P398H) selectively impairs gene expression in differentiated embryonic stem cells. Endocrinology 143: 2664-72 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Pelz HJ et al. (2005) The genetic basis of resistance to anticoagulants in rodents. Genetics 170: 1839-47 PubMed GONUTS page
- ↑ Rost S et al. (2004) Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2. Nature 427: 537-41 PubMed GONUTS page
