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MGI:Vegfc

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Vegfc ( synonyms: VEGF-C )
Protein Name(s) vascular endothelial growth factor C,
External Links
MGI MGI:109124

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001525

angiogenesis

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O35757

P

From MGI

GO:0002052

positive regulation of neuroblast proliferation

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:O35757

P

From MGI

GO:0005576

extracellular region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From MGI

GO:0005615

extracellular space

MGI:MGI:1201694
PMID:9247316[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From MGI

GO:0008083

growth factor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0339

F

From MGI

GO:0008083

growth factor activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000072

F

From MGI

GO:0008284

positive regulation of cell proliferation

MGI:MGI:1201694
PMID:9247316[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:95561

P

From MGI

GO:0008284

positive regulation of cell proliferation

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:O35757

P

From MGI

GO:0008284

positive regulation of cell proliferation

MGI:MGI:3620294
PMID:16462734[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3026650

P

From MGI

GO:0009887

organ morphogenesis

MGI:MGI:2686804
PMID:14634646[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3026650

P

From MGI

GO:0016020

membrane

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000072

C

From MGI

GO:0016331

morphogenesis of embryonic epithelium

MGI:MGI:2686804
PMID:14634646[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3026650

P

From MGI

GO:0030154

cell differentiation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0221

P

From MGI

GO:0030947

regulation of vascular endothelial growth factor receptor signaling pathway

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O35757

P

From MGI

GO:0031954

positive regulation of protein autophosphorylation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O35757

P

From MGI

GO:0042056

chemoattractant activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P49767

F

From MGI

GO:0043185

vascular endothelial growth factor receptor 3 binding

MGI:MGI:1201694
PMID:9247316[1]

IPI: Inferred from Physical Interaction

UniProtKB:P35917

F

From MGI

GO:0043185

vascular endothelial growth factor receptor 3 binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O35757

F

From MGI

GO:0043185

vascular endothelial growth factor receptor 3 binding

MGI:MGI:85073
PMID:9012504[4]

IPI: Inferred from Physical Interaction

UniProtKB:P35916

F

From MGI

GO:0043536

positive regulation of blood vessel endothelial cell migration

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O35757

P

From MGI

GO:0045776

negative regulation of blood pressure

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O35757

P

From MGI

GO:0048010

vascular endothelial growth factor receptor signaling pathway

MGI:MGI:1201694
PMID:9247316[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:95561

P

From MGI

GO:0048010

vascular endothelial growth factor receptor signaling pathway

MGI:MGI:85073
PMID:9012504[4]

IDA: Inferred from Direct Assay

P

From MGI

GO:0050679

positive regulation of epithelial cell proliferation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O35757

P

From MGI

GO:0050714

positive regulation of protein secretion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O35757

P

From MGI

GO:0050918

positive chemotaxis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P49767

P

From MGI

GO:0050930

induction of positive chemotaxis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P49767

P

From MGI

GO:0051781

positive regulation of cell division

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0497

P

From MGI

GO:0060754

positive regulation of mast cell chemotaxis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P49767

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Fitz LJ et al. (1997) Characterization of murine Flt4 ligand/VEGF-C. Oncogene 15: 613-8 PubMed GONUTS page
  2. Le Bras B et al. (2006) VEGF-C is a trophic factor for neural progenitors in the vertebrate embryonic brain. Nat Neurosci 9: 340-8 PubMed GONUTS page
  3. 3.0 3.1 Karkkainen MJ et al. (2004) Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins. Nat Immunol 5: 74-80 PubMed GONUTS page
  4. 4.0 4.1 Kukk E et al. (1996) VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development. Development 122: 3829-37 PubMed GONUTS page
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