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MGI:Vcam1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Vcam1 ( synonyms: CD106, Vcam-1 )
Protein Name(s) vascular cell adhesion molecule 1,
External Links
MGI MGI:98926

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0002102

podosome

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P19320

C

From MGI

GO:0005178

integrin binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P29534

F

From MGI

GO:0005178

integrin binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P19320

F

From MGI

GO:0005615

extracellular space

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P19320

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-1003

C

From MGI

GO:0005902

microvillus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P19320

C

From MGI

GO:0007155

cell adhesion

MGI:MGI:2180235
PMID:12021259[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007155

cell adhesion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P29534

P

From MGI

GO:0007155

cell adhesion

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P19320

P

From MGI

GO:0007157

heterophilic cell-cell adhesion

MGI:MGI:3757621
PMID:8145052[2]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0007157

heterophilic cell-cell adhesion

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P19320

P

From MGI

GO:0007159

leukocyte cell-cell adhesion

MGI:MGI:3757618
PMID:8562500[3]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0007159

leukocyte cell-cell adhesion

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P19320

P

From MGI

GO:0007507

heart development

MGI:MGI:70924
PMID:7539357[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857452

P

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P19320

C

From MGI

GO:0009986

cell surface

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P29534

C

From MGI

GO:0009986

cell surface

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P19320

C

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016020

membrane

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003987
InterPro:IPR003989

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR008424

C

From MGI

GO:0016337

cell-cell adhesion

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003987
InterPro:IPR003989

P

From MGI

GO:0030175

filopodium

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P19320

C

From MGI

GO:0031225

anchored to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0336

C

From MGI

GO:0042102

positive regulation of T cell proliferation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P19320

P

From MGI

GO:0042383

sarcolemma

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P29534

C

From MGI

GO:0044419

interspecies interaction between organisms

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0945

P

From MGI

GO:0045177

apical part of cell

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P19320

C

From MGI

GO:0050839

cell adhesion molecule binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P19320

F

From MGI

GO:0060669

embryonic placenta morphogenesis

MGI:MGI:70297
PMID:7530222[5]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2153830

P

From MGI

GO:0060710

chorio-allantoic fusion

MGI:MGI:70297
PMID:7530222[5]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2153830

P

From MGI

GO:0060710

chorio-allantoic fusion

MGI:MGI:70924
PMID:7539357[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857452

P

From MGI

GO:0061032

visceral serous pericardium development

MGI:MGI:4943617
PMID:20299672[6]

TAS: Traceable Author Statement

P

From MGI

GO:0071065

alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P19320

C

From MGI

GO:0071333

cellular response to glucose stimulus

MGI:MGI:3761912
PMID:17670746[7]

IDA: Inferred from Direct Assay

P

From MGI

GO:0071944

cell periphery

MGI:MGI:4949803
PMID:21464233[8]

IDA: Inferred from Direct Assay

C

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Sengbusch JK et al. (2002) Dual functions of [alpha]4[beta]1 integrin in epicardial development: initial migration and long-term attachment. J Cell Biol 157: 873-82 PubMed GONUTS page
  2. Hahne M et al. (1994) The heat-stable antigen can alter very late antigen 4-mediated adhesion. J Exp Med 179: 1391-5 PubMed GONUTS page
  3. Aigner S et al. (1995) Heat stable antigen (mouse CD24) supports myeloid cell binding to endothelial and platelet P-selectin. Int Immunol 7: 1557-65 PubMed GONUTS page
  4. 4.0 4.1 Kwee L et al. (1995) Defective development of the embryonic and extraembryonic circulatory systems in vascular cell adhesion molecule (VCAM-1) deficient mice. Development 121: 489-503 PubMed GONUTS page
  5. 5.0 5.1 Gurtner GC et al. (1995) Targeted disruption of the murine VCAM1 gene: essential role of VCAM-1 in chorioallantoic fusion and placentation. Genes Dev 9: 1-14 PubMed GONUTS page
  6. Olivey HE & Svensson EC (2010) Epicardial-myocardial signaling directing coronary vasculogenesis. Circ Res 106: 818-32 PubMed GONUTS page
  7. Yao D et al. (2007) High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A. J Biol Chem 282: 31038-45 PubMed GONUTS page
  8. Osorio KM et al. (2011) Runx1 modulates adult hair follicle stem cell emergence and maintenance from distinct embryonic skin compartments. J Cell Biol 193: 235-50 PubMed GONUTS page
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