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MGI:Usp8
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Usp8 ( synonyms: Ubpy ) | |
| Protein Name(s) | ubiquitin specific peptidase 8, | |
| External Links | ||
| MGI | MGI:1934029 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004221 |
ubiquitin thiolesterase activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0004843 |
ubiquitin-specific protease activity |
MGI:MGI:2151978 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004843 |
ubiquitin-specific protease activity |
MGI:MGI:3620312 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004843 |
ubiquitin-specific protease activity |
MGI:MGI:4821940 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004843 |
ubiquitin-specific protease activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:1933849 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3054509 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3620312 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4821940 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:2151978 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:2151978 |
IPI: Inferred from Physical Interaction |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0539 |
C |
From MGI |
||
| GO:0005737 |
cytoplasm |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0963 |
C |
From MGI |
||
| GO:0005768 |
endosome |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0967 |
C |
From MGI |
||
| GO:0005769 |
early endosome |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:3620312 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-1003 |
C |
From MGI |
||
| GO:0006508 |
proteolysis |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0645 |
P |
From MGI |
||
| GO:0006511 |
ubiquitin-dependent protein catabolic process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007032 |
endosome organization |
MGI:MGI:4821940 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0007032 |
endosome organization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007049 |
cell cycle |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0131 |
P |
From MGI |
||
| GO:0007265 |
Ras protein signal transduction |
MGI:MGI:2151978 |
IPI: Inferred from Physical Interaction |
P |
From MGI |
|||
| GO:0008233 |
peptidase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0645 |
F |
From MGI |
||
| GO:0008234 |
cysteine-type peptidase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0788 |
F |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016579 |
protein deubiquitination |
MGI:MGI:3054509 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0016579 |
protein deubiquitination |
MGI:MGI:3620312 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0016579 |
protein deubiquitination |
MGI:MGI:4821940 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0016787 |
hydrolase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0378 |
F |
From MGI |
||
| GO:0017124 |
SH3 domain binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0729 |
F |
From MGI |
||
| GO:0019897 |
extrinsic to plasma membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0031313 |
extrinsic to endosome membrane |
MGI:MGI:3620312 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0070536 |
protein K63-linked deubiquitination |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0071108 |
protein K48-linked deubiquitination |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Gnesutta N et al. (2001) Cloning and characterization of mouse UBPy, a deubiquitinating enzyme that interacts with the ras guanine nucleotide exchange factor CDC25(Mm)/Ras-GRF1. J Biol Chem 276: 39448-54 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Mizuno E et al. (2005) Regulation of epidermal growth factor receptor down-regulation by UBPY-mediated deubiquitination at endosomes. Mol Biol Cell 16: 5163-74 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Mizuno E et al. (2006) A deubiquitinating enzyme UBPY regulates the level of protein ubiquitination on endosomes. Traffic 7: 1017-31 PubMed GONUTS page
- ↑ Kato M et al. (2000) A deubiquitinating enzyme UBPY interacts with the Src homology 3 domain of Hrs-binding protein via a novel binding motif PX(V/I)(D/N)RXXKP. J Biol Chem 275: 37481-7 PubMed GONUTS page
- ↑ 5.0 5.1 Wu X et al. (2004) Stabilization of the E3 ubiquitin ligase Nrdp1 by the deubiquitinating enzyme USP8. Mol Cell Biol 24: 7748-57 PubMed GONUTS page
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