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MGI:Ush2a
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Ush2a ( synonyms: LOC269160, LOC381317, MUSH2A, Usherin ) | |
| Protein Name(s) | Usher syndrome 2A (autosomal recessive, mild) homolog (human), | |
| External Links | ||
| MGI | MGI:1341292 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0002142 |
stereocilia ankle link complex |
MGI:MGI:3714249 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3714249 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005518 |
collagen binding |
MGI:MGI:3028449 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005518 |
collagen binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005576 |
extracellular region |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0964 |
C |
From MGI |
||
| GO:0005604 |
basement membrane |
MGI:MGI:3028449 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005604 |
basement membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-1003 |
C |
From MGI |
||
| GO:0007601 |
visual perception |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0844 |
P |
From MGI |
||
| GO:0007605 |
sensory perception of sound |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0016324 |
apical plasma membrane |
MGI:MGI:3700725 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0017022 |
myosin binding |
MGI:MGI:3714249 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0032421 |
stereocilium bundle |
MGI:MGI:3700725 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0042995 |
cell projection |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0966 |
C |
From MGI |
||
| GO:0045494 |
photoreceptor cell maintenance |
MGI:MGI:3700725 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3702040 |
P |
From MGI |
||
| GO:0045494 |
photoreceptor cell maintenance |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0048496 |
maintenance of organ identity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0050896 |
response to stimulus |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0716 |
P |
From MGI |
||
| GO:0050953 |
sensory perception of light stimulus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0060113 |
inner ear receptor cell differentiation |
MGI:MGI:3700725 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3702040 |
P |
From MGI |
||
|
colocalizes_with |
GO:0001917 |
photoreceptor inner segment |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001231686 |
C |
From MGI |
|
|
colocalizes_with |
GO:0032391 |
photoreceptor connecting cilium |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001231686 |
C |
From MGI |
|
|
colocalizes_with |
GO:0043025 |
neuronal cell body |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001231686 |
C |
From MGI |
|
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Michalski N et al. (2007) Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning. J Neurosci 27: 6478-88 PubMed GONUTS page
- ↑ 2.0 2.1 Bhattacharya G et al. (2004) A domain-specific usherin/collagen IV interaction may be required for stable integration into the basement membrane superstructure. J Cell Sci 117: 233-42 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Liu X et al. (2007) Usherin is required for maintenance of retinal photoreceptors and normal development of cochlear hair cells. Proc Natl Acad Sci U S A 104: 4413-8 PubMed GONUTS page
