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MGI:Usf2

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Usf2 ( synonyms: bHLHb12, Usf-2 )
Protein Name(s) upstream transcription factor 2,
External Links
MGI MGI:99961

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000432

positive regulation of transcription from RNA polymerase II promoter by glucose

MGI:MGI:1330677
PMID:9890958[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0000432

positive regulation of transcription from RNA polymerase II promoter by glucose

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q15853

P

From MGI

GO:0000978

RNA polymerase II core promoter proximal region sequence-specific DNA binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q63665

F

From MGI

GO:0003677

DNA binding

MGI:MGI:68619
PMID:7523363[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003690

double-stranded DNA binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q63665

F

From MGI

GO:0003700

sequence-specific DNA binding transcription factor activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q63665

F

From MGI

GO:0003705

RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q15853

F

From MGI

GO:0005634

nucleus

MGI:MGI:2679398
PMID:12907752[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005634

nucleus

MGI:MGI:3530402
PMID:15661922[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005634

nucleus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q63665

C

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q15853

C

From MGI

GO:0006351

transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From MGI

GO:0006357

regulation of transcription from RNA polymerase II promoter

MGI:MGI:68619
PMID:7523363[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006357

regulation of transcription from RNA polymerase II promoter

MGI:MGI:68619
PMID:7523363[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007595

lactation

MGI:MGI:2679398
PMID:12907752[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2181680

P

From MGI

GO:0042803

protein homodimerization activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q63665

F

From MGI

GO:0042803

protein homodimerization activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q15853

F

From MGI

GO:0043425

bHLH transcription factor binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q15853

F

From MGI

GO:0043565

sequence-specific DNA binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q63665

F

From MGI

GO:0043565

sequence-specific DNA binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q15853

F

From MGI

GO:0045893

positive regulation of transcription, DNA-dependent

MGI:MGI:3529622
PMID:15466854[5]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q63665

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q15853

P

From MGI

GO:0046982

protein heterodimerization activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q63665

F

From MGI

GO:0046982

protein heterodimerization activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q15853

F

From MGI

GO:0055088

lipid homeostasis

MGI:MGI:1330677
PMID:9890958[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

contributes_to

GO:0003705

RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q63665

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Casado M et al. (1999) Essential role in vivo of upstream stimulatory factors for a normal dietary response of the fatty acid synthase gene in the liver. J Biol Chem 274: 2009-13 PubMed GONUTS page
  2. 2.0 2.1 2.2 Lin Q et al. (1994) Archaic structure of the gene encoding transcription factor USF. J Biol Chem 269: 23894-903 PubMed GONUTS page
  3. 3.0 3.1 Hadsell DL et al. (2003) Diminished milk synthesis in upstream stimulatory factor 2 null mice is associated with decreased circulating oxytocin and decreased mammary gland expression of eukaryotic initiation factors 4E and 4G. Mol Endocrinol 17: 2251-67 PubMed GONUTS page
  4. O'Connell RM et al. (2005) Immune activation of type I IFNs by Listeria monocytogenes occurs independently of TLR4, TLR2, and receptor interacting protein 2 but involves TNFR-associated NF kappa B kinase-binding kinase 1. J Immunol 174: 1602-7 PubMed GONUTS page
  5. Firlej V et al. (2005) Pea3 transcription factor cooperates with USF-1 in regulation of the murine bax transcription without binding to an Ets-binding site. J Biol Chem 280: 887-98 PubMed GONUTS page
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