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MGI:Ung

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Ung ( synonyms: UNG1 )
Protein Name(s) uracil DNA glycosylase,
External Links
MGI MGI:109352

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004844

uracil DNA N-glycosylase activity

MGI:MGI:1859986
PMID:10871356[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004844

uracil DNA N-glycosylase activity

MGI:MGI:3513244
PMID:15494304[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2182610

F

From MGI

GO:0004844

uracil DNA N-glycosylase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001013142

F

From MGI

GO:0005634

nucleus

MGI:MGI:1859986
PMID:10871356[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:1859986
PMID:10871356[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:2682130
PMID:14651853[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:3852644
PMID:18614015[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001013142

C

From MGI

GO:0006281

DNA repair

MGI:MGI:1859986
PMID:10871356[1]

TAS: Traceable Author Statement

P

From MGI

GO:0006284

base-excision repair

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001013142

P

From MGI

GO:0006974

response to DNA damage stimulus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0227

P

From MGI

GO:0016446

somatic hypermutation of immunoglobulin genes

MGI:MGI:3513244
PMID:15494304[2]

IGI: Inferred from Genetic Interaction

MGI:MGI:101816

P

From MGI

GO:0016447

somatic recombination of immunoglobulin gene segments

MGI:MGI:3513244
PMID:15494304[2]

IGI: Inferred from Genetic Interaction

MGI:MGI:101816

P

From MGI

GO:0016447

somatic recombination of immunoglobulin gene segments

MGI:MGI:3513244
PMID:15494304[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2182610

P

From MGI

GO:0016787

hydrolase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From MGI

GO:0016798

hydrolase activity, acting on glycosyl bonds

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0326

F

From MGI

GO:0016799

hydrolase activity, hydrolyzing N-glycosyl compounds

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR018085

F

From MGI

GO:0043066

negative regulation of apoptotic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001013142

P

From MGI

GO:0045437

uridine nucleosidase activity

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:3.2.2.3

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Nilsen H et al. (2000) Analysis of uracil-DNA glycosylases from the murine Ung gene reveals differential expression in tissues and in embryonic development and a subcellular sorting pattern that differs from the human homologues. Nucleic Acids Res 28: 2277-85 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Rada C et al. (2004) Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation. Mol Cell 16: 163-71 PubMed GONUTS page
  3. Mootha VK et al. (2003) Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell 115: 629-40 PubMed GONUTS page
  4. Pagliarini DJ et al. (2008) A mitochondrial protein compendium elucidates complex I disease biology. Cell 134: 112-23 PubMed GONUTS page
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