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MGI:Unc93b1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Unc93b1 | |
| Protein Name(s) | unc-93 homolog B1 (C. elegans), | |
| External Links | ||
| MGI | MGI:1859307 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0002224 |
toll-like receptor signaling pathway |
MGI:MGI:3615690 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3619211 |
P |
From MGI |
||
| GO:0005622 |
intracellular |
MGI:MGI:3776596 |
IMP: Inferred from Mutant Phenotype |
C |
From MGI |
|||
| GO:0005764 |
lysosome |
MGI:MGI:3776596 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005768 |
endosome |
MGI:MGI:3776596 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005768 |
endosome |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005783 |
endoplasmic reticulum |
MGI:MGI:3615690 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005783 |
endoplasmic reticulum |
MGI:MGI:4457250 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005783 |
endoplasmic reticulum |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006886 |
intracellular protein transport |
MGI:MGI:3776596 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0009615 |
response to virus |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0051 |
P |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0019886 |
antigen processing and presentation of exogenous peptide antigen via MHC class II |
MGI:MGI:3615690 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3619211 |
P |
From MGI |
||
| GO:0031410 |
cytoplasmic vesicle |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0968 |
C |
From MGI |
||
| GO:0032009 |
early phagosome |
MGI:MGI:3776596 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0034138 |
toll-like receptor 3 signaling pathway |
MGI:MGI:3615690 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0034138 |
toll-like receptor 3 signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0034154 |
toll-like receptor 7 signaling pathway |
MGI:MGI:3615690 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0034154 |
toll-like receptor 7 signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0034162 |
toll-like receptor 9 signaling pathway |
MGI:MGI:3615690 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0034162 |
toll-like receptor 9 signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0035325 |
Toll-like receptor binding |
MGI:MGI:4457250 |
IPI: Inferred from Physical Interaction |
UniProtKB:P58681 |
F |
From MGI |
||
| GO:0045087 |
innate immune response |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0399 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Tabeta K et al. (2006) The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9. Nat Immunol 7: 156-64 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Kim YM et al. (2008) UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes. Nature 452: 234-8 PubMed GONUTS page
- ↑ 3.0 3.1 Brinkmann MM et al. (2007) The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling. J Cell Biol 177: 265-75 PubMed GONUTS page
