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MGI:Ucp3

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Ucp3 ( synonyms: Slc25a9, UCP-3 )
Protein Name(s) uncoupling protein 3 (mitochondrial, proton carrier),
External Links
MGI MGI:1099787

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000303

response to superoxide

MGI:MGI:2183181
PMID:11780125[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2183204

P

From MGI

GO:0000303

response to superoxide

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P56499

P

From MGI

GO:0001666

response to hypoxia

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P56499

P

From MGI

GO:0005739

mitochondrion

MGI:MGI:2157174
PMID:11707458[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2183204

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:2682130
PMID:14651853[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:3852644
PMID:18614015[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P56499

C

From MGI

GO:0005743

mitochondrial inner membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0999

C

From MGI

GO:0006631

fatty acid metabolic process

MGI:MGI:1858712
PMID:10748196[5]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2183166

P

From MGI

GO:0006810

transport

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0813

P

From MGI

GO:0006839

mitochondrial transport

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR002030

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From MGI

GO:0017077

oxidative phosphorylation uncoupler activity

MGI:MGI:1858711
PMID:10748195[6]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2183202

F

From MGI

GO:0017077

oxidative phosphorylation uncoupler activity

MGI:MGI:1858712
PMID:10748196[5]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2183166

F

From MGI

GO:0031966

mitochondrial membrane

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR002030

C

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Echtay KS et al. (2002) Superoxide activates mitochondrial uncoupling proteins. Nature 415: 96-9 PubMed GONUTS page
  2. Cadenas S et al. (2002) The basal proton conductance of skeletal muscle mitochondria from transgenic mice overexpressing or lacking uncoupling protein-3. J Biol Chem 277: 2773-8 PubMed GONUTS page
  3. Mootha VK et al. (2003) Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell 115: 629-40 PubMed GONUTS page
  4. Pagliarini DJ et al. (2008) A mitochondrial protein compendium elucidates complex I disease biology. Cell 134: 112-23 PubMed GONUTS page
  5. 5.0 5.1 Vidal-Puig AJ et al. (2000) Energy metabolism in uncoupling protein 3 gene knockout mice. J Biol Chem 275: 16258-66 PubMed GONUTS page
  6. Gong DW et al. (2000) Lack of obesity and normal response to fasting and thyroid hormone in mice lacking uncoupling protein-3. J Biol Chem 275: 16251-7 PubMed GONUTS page
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