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MGI:Ube4b
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Ube4b ( synonyms: D4Bwg0973e, UFD2, UFD2a, Ufd2p ) | |
| Protein Name(s) | ubiquitination factor E4B, UFD2 homolog (S. cerevisiae), | |
| External Links | ||
| MGI | MGI:1927086 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000151 |
ubiquitin ligase complex |
MGI:MGI:2449210 |
TAS: Traceable Author Statement |
C |
From MGI |
|||
| GO:0000209 |
protein polyubiquitination |
MGI:MGI:2149486 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0000209 |
protein polyubiquitination |
MGI:MGI:3610695 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3611069 |
P |
From MGI |
||
| GO:0003222 |
ventricular trabecula myocardium morphogenesis |
MGI:MGI:3610695 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3611069 |
P |
From MGI |
||
| GO:0004842 |
ubiquitin-protein ligase activity |
MGI:MGI:2149486 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004842 |
ubiquitin-protein ligase activity |
MGI:MGI:2449210 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0004842 |
ubiquitin-protein ligase activity |
MGI:MGI:4441570 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004842 |
ubiquitin-protein ligase activity |
MGI:MGI:4833839 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:2449210 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4833839 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:2149486 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:2449210 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006457 |
protein folding |
MGI:MGI:2449210 |
NAS: Non-traceable Author Statement |
P |
From MGI |
|||
| GO:0006511 |
ubiquitin-dependent protein catabolic process |
MGI:MGI:2449210 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0006511 |
ubiquitin-dependent protein catabolic process |
MGI:MGI:3610695 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3611069 |
P |
From MGI |
||
| GO:0006915 |
apoptotic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0009411 |
response to UV |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016567 |
protein ubiquitination |
MGI:MGI:4833839 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0019899 |
enzyme binding |
MGI:MGI:2449210 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0031175 |
neuron projection development |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
RefSeq:XP_233679.3 |
P |
From MGI |
||
| GO:0031175 |
neuron projection development |
MGI:MGI:3610695 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3611069 |
P |
From MGI |
||
| GO:0034450 |
ubiquitin-ubiquitin ligase activity |
MGI:MGI:2149486 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0034976 |
response to endoplasmic reticulum stress |
MGI:MGI:3610695 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3611069 |
P |
From MGI |
||
| GO:0042787 |
protein ubiquitination involved in ubiquitin-dependent protein catabolic process |
MGI:MGI:2449210 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0044257 |
cellular protein catabolic process |
MGI:MGI:3610695 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3611069 |
P |
From MGI |
||
| GO:0051082 |
unfolded protein binding |
MGI:MGI:2449210 |
NAS: Non-traceable Author Statement |
F |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Kaneko C et al. (2003) Characterization of the mouse gene for the U-box-type ubiquitin ligase UFD2a. Biochem Biophys Res Commun 300: 297-304 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Hatakeyama S et al. (2001) U box proteins as a new family of ubiquitin-protein ligases. J Biol Chem 276: 33111-20 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 Kaneko-Oshikawa C et al. (2005) Mammalian E4 is required for cardiac development and maintenance of the nervous system. Mol Cell Biol 25: 10953-64 PubMed GONUTS page
- ↑ Nordquist KA et al. (2010) Structural and functional characterization of the monomeric U-box domain from E4B. Biochemistry 49: 347-55 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Okumura F et al. (2004) Functional regulation of FEZ1 by the U-box-type ubiquitin ligase E4B contributes to neuritogenesis. J Biol Chem 279: 53533-43 PubMed GONUTS page