GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
MGI:Ube2n
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Ube2n ( synonyms: UBC13 ) | |
| Protein Name(s) | ubiquitin-conjugating enzyme E2N, | |
| External Links | ||
| MGI | MGI:1934835 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000151 |
ubiquitin ligase complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0000166 |
nucleotide binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0547 |
F |
From MGI |
||
| GO:0000724 |
double-strand break repair via homologous recombination |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0000729 |
DNA double-strand break processing |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0004842 |
ubiquitin-protein ligase activity |
MGI:MGI:2178180 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004842 |
ubiquitin-protein ligase activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_446380 |
F |
From MGI |
||
| GO:0004842 |
ubiquitin-protein ligase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:2178180 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005524 |
ATP binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0067 |
F |
From MGI |
||
| GO:0005634 |
nucleus |
MGI:MGI:3055251 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006281 |
DNA repair |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0234 |
P |
From MGI |
||
| GO:0006301 |
postreplication repair |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006511 |
ubiquitin-dependent protein catabolic process |
MGI:MGI:2178180 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006974 |
response to DNA damage stimulus |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0227 |
P |
From MGI |
||
| GO:0016567 |
protein ubiquitination |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_446380 |
P |
From MGI |
||
| GO:0016567 |
protein ubiquitination |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016574 |
histone ubiquitination |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016874 |
ligase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0436 |
F |
From MGI |
||
| GO:0016881 |
acid-amino acid ligase activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0031058 |
positive regulation of histone modification |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0031372 |
UBC13-MMS2 complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0033182 |
regulation of histone ubiquitination |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0035370 |
UBC13-UEV1A complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0043123 |
positive regulation of I-kappaB kinase/NF-kappaB cascade |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043130 |
ubiquitin binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0045739 |
positive regulation of DNA repair |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0050852 |
T cell receptor signaling pathway |
MGI:MGI:3715075 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From MGI |
|||
| GO:0050852 |
T cell receptor signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0051092 |
positive regulation of NF-kappaB transcription factor activity |
MGI:MGI:3715077 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From MGI |
|||
| GO:0051092 |
positive regulation of NF-kappaB transcription factor activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0051443 |
positive regulation of ubiquitin-protein ligase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0070534 |
protein K63-linked ubiquitination |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Ashley C et al. (2002) Roles of mouse UBC13 in DNA postreplication repair and Lys63-linked ubiquitination. Gene 285: 183-91 PubMed GONUTS page
- ↑ van der Laan R et al. (2004) Ubiquitin ligase Rad18Sc localizes to the XY body and to other chromosomal regions that are unpaired and transcriptionally silenced during male meiotic prophase. J Cell Sci 117: 5023-33 PubMed GONUTS page
- ↑ Sun L et al. (2004) The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes. Mol Cell 14: 289-301 PubMed GONUTS page
- ↑ Zhou H et al. (2004) Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO. Nature 427: 167-71 PubMed GONUTS page
