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MGI:Twsg1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Twsg1 ( synonyms: D17Ertd403e, Tsg ) | |
| Protein Name(s) | twisted gastrulation homolog 1 (Drosophila), | |
| External Links | ||
| MGI | MGI:2137520 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001503 |
ossification |
MGI:MGI:2654977 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2655736 |
P |
From MGI |
||
| GO:0001707 |
mesoderm formation |
MGI:MGI:3578079 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:103302 |
P |
From MGI |
||
| GO:0005515 |
protein binding |
MGI:MGI:3525426 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3578079 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005576 |
extracellular region |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0964 |
C |
From MGI |
||
| GO:0005615 |
extracellular space |
MGI:MGI:3577114 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0007435 |
salivary gland morphogenesis |
MGI:MGI:3830176 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3830633 |
P |
From MGI |
||
| GO:0009790 |
embryo development |
MGI:MGI:3037153 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2655736 |
P |
From MGI |
||
| GO:0009888 |
tissue development |
MGI:MGI:3043486 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:88180 |
P |
From MGI |
||
| GO:0030097 |
hemopoiesis |
MGI:MGI:2654977 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2655736 |
P |
From MGI |
||
| GO:0030154 |
cell differentiation |
MGI:MGI:3043486 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3044357 |
P |
From MGI |
||
| GO:0030509 |
BMP signaling pathway |
MGI:MGI:3043486 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:88180 |
P |
From MGI |
||
| GO:0030513 |
positive regulation of BMP signaling pathway |
MGI:MGI:2654977 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2655736 |
P |
From MGI |
||
| GO:0030514 |
negative regulation of BMP signaling pathway |
MGI:MGI:2654977 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2655736 |
P |
From MGI |
||
| GO:0030514 |
negative regulation of BMP signaling pathway |
MGI:MGI:3577114 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0030900 |
forebrain development |
MGI:MGI:3037153 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2655736 |
P |
From MGI |
||
| GO:0030900 |
forebrain development |
MGI:MGI:3043486 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:88180 |
P |
From MGI |
||
| GO:0043010 |
camera-type eye development |
MGI:MGI:3043486 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:88180 |
P |
From MGI |
||
| GO:0045668 |
negative regulation of osteoblast differentiation |
MGI:MGI:3577114 |
IDA: Inferred from Direct Assay |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Nosaka T et al. (2003) Mammalian twisted gastrulation is essential for skeleto-lymphogenesis. Mol Cell Biol 23: 2969-80 PubMed GONUTS page
- ↑ 2.0 2.1 Zakin L et al. (2005) Sirenomelia in Bmp7 and Tsg compound mutant mice: requirement for Bmp signaling in the development of ventral posterior mesoderm. Development 132: 2489-99 PubMed GONUTS page
- ↑ Jasuja R et al. (2004) Cell-surface heparan sulfate proteoglycans potentiate chordin antagonism of bone morphogenetic protein signaling and are necessary for cellular uptake of chordin. J Biol Chem 279: 51289-97 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Petryk A et al. (2005) Twisted gastrulation and chordin inhibit differentiation and mineralization in MC3T3-E1 osteoblast-like cells. Bone 36: 617-26 PubMed GONUTS page
- ↑ Melnick M et al. (2006) Embryonic salivary gland dysmorphogenesis in Twisted gastrulation deficient mice. Arch Oral Biol 51: 433-8 PubMed GONUTS page
- ↑ 6.0 6.1 Petryk A et al. (2004) The mammalian twisted gastrulation gene functions in foregut and craniofacial development. Dev Biol 267: 374-86 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 7.3 7.4 Zakin L & De Robertis EM (2004) Inactivation of mouse Twisted gastrulation reveals its role in promoting Bmp4 activity during forebrain development. Development 131: 413-24 PubMed GONUTS page
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