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MGI:Twf2
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Twf2 ( synonyms: A6-related, Ptk9l, Twf2, Twinfilin-2 ) | |
| Protein Name(s) | twinfilin, actin-binding protein, homolog 2 (Drosophila), | |
| External Links | ||
| MGI | MGI:1346078 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003779 |
actin binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0009 |
F |
From MGI |
||
| GO:0003779 |
actin binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0003785 |
actin monomer binding |
MGI:MGI:2673741 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003785 |
actin monomer binding |
MGI:MGI:3840765 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005080 |
protein kinase C binding |
MGI:MGI:1341446 |
ISA: Inferred from Sequence Alignment |
EMBL:Y17169 |
F |
From MGI |
||
| GO:0005080 |
protein kinase C binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005524 |
ATP binding |
MGI:MGI:1341446 |
ISA: Inferred from Sequence Alignment |
EMBL:Y17169 |
F |
From MGI |
||
| GO:0005524 |
ATP binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005546 |
phosphatidylinositol-4,5-bisphosphate binding |
MGI:MGI:2673741 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:1341446 |
ISA: Inferred from Sequence Alignment |
EMBL:Y17169 |
C |
From MGI |
||
| GO:0005856 |
cytoskeleton |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0206 |
C |
From MGI |
||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0010592 |
positive regulation of lamellipodium assembly |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0010976 |
positive regulation of neuron projection development |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030016 |
myofibril |
MGI:MGI:3840765 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0030027 |
lamellipodium |
MGI:MGI:2673741 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0030030 |
cell projection organization |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0970 |
P |
From MGI |
||
| GO:0030175 |
filopodium |
MGI:MGI:2673741 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0030426 |
growth cone |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0030837 |
negative regulation of actin filament polymerization |
MGI:MGI:2673741 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0032420 |
stereocilium |
MGI:MGI:5285166 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0032532 |
regulation of microvillus length |
MGI:MGI:5285166 |
IC: Inferred by Curator |
GO:0032420 |
P |
From MGI |
||
| GO:0032956 |
regulation of actin cytoskeleton organization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0035556 |
intracellular signal transduction |
MGI:MGI:1341446 |
ISA: Inferred from Sequence Alignment |
EMBL:Y17169 |
P |
From MGI |
||
| GO:0042989 |
sequestering of actin monomers |
MGI:MGI:3840765 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0042995 |
cell projection |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0966 |
C |
From MGI |
||
| GO:0045773 |
positive regulation of axon extension |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0048471 |
perinuclear region of cytoplasm |
MGI:MGI:2673741 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0051016 |
barbed-end actin filament capping |
MGI:MGI:3840765 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0071300 |
cellular response to retinoic acid |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0071363 |
cellular response to growth factor stimulus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Vartiainen MK et al. (2003) Mammals have two twinfilin isoforms whose subcellular localizations and tissue distributions are differentially regulated. J Biol Chem 278: 34347-55 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Nevalainen EM et al. (2009) Two biochemically distinct and tissue-specific twinfilin isoforms are generated from the mouse Twf2 gene by alternative promoter usage. Biochem J 417: 593-600 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Rohwer A et al. (1999) Cloning, expression and characterization of an A6-related protein. Eur J Biochem 263: 518-25 PubMed GONUTS page
- ↑ 4.0 4.1 Peng AW et al. (2009) Twinfilin 2 regulates actin filament lengths in cochlear stereocilia. J Neurosci 29: 15083-8 PubMed GONUTS page
