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MGI:Tub

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Tub ( synonyms: rd5, tub )
Protein Name(s) tubby candidate gene,
External Links
MGI MGI:2651573

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005515

protein binding

MGI:MGI:4441109
PMID:19837063[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q9Z273

F

From MGI

GO:0005576

extracellular region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From MGI

GO:0005634

nucleus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

From MGI

GO:0005829

cytosol

MGI:MGI:2177887
PMID:11925566[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1861349

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-1003

C

From MGI

GO:0006909

phagocytosis

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0581

P

From MGI

GO:0007602

phototransduction

MGI:MGI:1352376
PMID:10629044[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857081

P

From MGI

GO:0007605

sensory perception of sound

MGI:MGI:2177887
PMID:11925566[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1861349

P

From MGI

GO:0007605

sensory perception of sound

MGI:MGI:4849309
PMID:21052544[4]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0008020

G-protein coupled photoreceptor activity

MGI:MGI:1352376
PMID:10629044[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857081

F

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0043231

intracellular membrane-bounded organelle

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:E9PQR4

C

From MGI

GO:0044259

multicellular organismal macromolecule metabolic process

MGI:MGI:4849308
PMID:21056012[5]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0050766

positive regulation of phagocytosis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P50607

P

From MGI

GO:0050896

response to stimulus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0716

P

From MGI

GO:0060041

retina development in camera-type eye

MGI:MGI:4849309
PMID:21052544[4]

IMP: Inferred from Mutant Phenotype

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Caberoy NB et al. (2010) Identification of tubby and tubby-like protein 1 as eat-me signals by phage display. Exp Cell Res 316: 245-57 PubMed GONUTS page
  2. 2.0 2.1 Ikeda A et al. (2002) Microtubule-associated protein 1A is a modifier of tubby hearing (moth1). Nat Genet 30: 401-5 PubMed GONUTS page
  3. 3.0 3.1 Stubdal H et al. (2000) Targeted deletion of the tub mouse obesity gene reveals that tubby is a loss-of-function mutation. Mol Cell Biol 20: 878-82 PubMed GONUTS page
  4. 4.0 4.1 Won J et al. (2011) Mouse model resources for vision research. J Ophthalmol 2011: 391384 PubMed GONUTS page
  5. Skoulidis F et al. (2010) Germline Brca2 heterozygosity promotes Kras(G12D) -driven carcinogenesis in a murine model of familial pancreatic cancer. Cancer Cell 18: 499-509 PubMed GONUTS page
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